- Gastric Cancer Management and Outcomes
- Gastrointestinal Tumor Research and Treatment
- Metastasis and carcinoma case studies
- Lung Cancer Treatments and Mutations
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Esophageal Cancer Research and Treatment
- Helicobacter pylori-related gastroenterology studies
- Colorectal Cancer Treatments and Studies
- Esophageal and GI Pathology
- Cancer Immunotherapy and Biomarkers
- Seismic Imaging and Inversion Techniques
- Facial Nerve Paralysis Treatment and Research
- Hepatocellular Carcinoma Treatment and Prognosis
- Bariatric Surgery and Outcomes
- Cancer Treatment and Pharmacology
- Colorectal Cancer Surgical Treatments
- Cancer, Hypoxia, and Metabolism
- Colorectal and Anal Carcinomas
- Cancer Mechanisms and Therapy
- Seismic Waves and Analysis
- Peripheral Nerve Disorders
- Metabolism, Diabetes, and Cancer
- Hydraulic Fracturing and Reservoir Analysis
- Vascular Procedures and Complications
Central South University
2024
Southern Medical University
2013-2023
Nanfang Hospital
2013-2023
Bengbu Medical College
2019-2021
AstraZeneca (Japan)
2019
Fujian Medical University
2016
Fujian Provincial Cancer Hospital
2016
Zhongshan Hospital
2016
Wuhan General Hospital of Guangzhou
2013
General Hospital of Guangzhou Military Command
2013
Abstract China is one of the countries with highest incidence gastric cancer. There are differences in epidemiological characteristics, clinicopathological features, tumor biological treatment patterns, and drug selection between cancer patients from Eastern Western countries. Non‐Chinese guidelines cannot specifically reflect diagnosis characteristics for Chinese patients. The Society Clinical Oncology (CSCO) arranged a panel senior experts specializing all sub‐specialties to compile,...
The safety and efficacy of radical laparoscopic distal gastrectomy (LG) with D2 lymphadenectomy for the treatment advanced gastric cancer (AGC) remain controversial. We conducted a randomized controlled trial to compare conventional open lymph node dissections AGC.Between September 2012 December 2014, 1,056 patients clinical stage T2-4aN0-3M0 were eligible inclusion. They randomly assigned either LG group (n = 528) or (OG) 528). Fifteen experienced surgeons from 14 institutions in China...
There exist differences in the epidemiological characteristics, clinicopathological features, tumor biological treatment patterns, and drug selections between gastric cancer patients from Eastern Western countries. The Chinese Society of Clinical Oncology (CSCO) has organized a panel senior experts specializing all sub-specialties to compile clinical guideline for diagnosis since 2016 renews it annually. Taking into account regional differences, giving full consideration accessibility...
The current staging system of gastric cancer is not adequate for defining a prognosis and predicting the patients most likely to benefit from chemotherapy.To construct survival prediction model based on specific tumor patient characteristics that enables individualized predictions net adjuvant chemotherapy with stage II or III cancer.In this multicenter retrospective analysis, was constructed using data training cohort 746 who satisfied study's inclusion criteria underwent surgery between...
IntroductionTwo clinical studies (Study 1108 and ATLANTIC) were analyzed to evaluate the prognostic value of baseline liver metastases (LMs) in advanced/metastatic non–small-cell lung cancer patients treated with durvalumab 10 mg/kg every 2 weeks.Patients MethodsA multivariate Cox proportional hazards analysis was conducted; covariates included performance status, tumor stage, histology, sex, age, smoking programmed cell death ligand 1 (PD-L1) status.ResultsIn all, 569 included. LMs present...
Purpose: Population-based data on the proportion and prognosis of liver metastases at diagnosis gastric cancer are currently lacking.Besides, treatment with is still controversial now.Methods: Patients (GCLM) time in advanced were identified using Surveillance, Epidemiology, End Result (SEER) database National Cancer Institute.Multivariable logistic Cox regression performed to identify predictors presence GCLM factors associated all-cause mortality. Results:We 3507 patients diagnosis,...
The present study was performed to evaluate the predictive capacity of 8th edition vs. 7th American Joint Committee on Cancer (AJCC) tumor-node-metastasis (TNM) staging system for overall survival (OS) patients with gastric cancer. Data eligible cancer in our institution between June 2004 and 2014 were retrospectively reviewed. A total 1,506 followed up July 2016, among whom 1,484 complete stage information included TNM analysis. 339 (22.8%) presented migration, including 325 (21.9%)...
Intracorporeal esophagojejunostomy via a transorally inserted-anvil method during laparoscopic total gastrectomy (LTG) for upper gastric cancer has been demonstrated to be feasible, but the use of this assessment exclusively Siewert type 2 adenocarcinoma esophagogastric junction (AEG) not reported. A 428 consecutive gastric-cancer patients who underwent LTG in Nanfang Hospital from January 2008 December 2016 were reviewed. Among these patients, 98 classified as AEG. The intracorporeal...
Feasibility and nutritional impact of laparoscopic assisted tailored subtotal gastrectomy for middle-third gastric cancer
Intracorporeal Roux-en-Y esophagojejunostomy during laparoscopic total gastrectomy for gastric cancer remains a challenging manipulation due to the uncontrolled direction of jejunal side or unintended embedded tissues, although several methods have been introduced. In this study, we simplified procedure based on surgical string fixing technique using transorally inserted anvil (OrVil™; Covidien Ltd., Mansfield, MA, USA). From March 2012 September 2013, 14 consecutive patients underwent...
Laparoscopy-assisted distal gastrectomy (LDG) combined with D2 lymphadenectomy may be safely performed in patients advanced gastric cancer (AGC) by experienced surgeons at specialized high-volume institutions as shown the Chinese Laparoscopic Gastrointestinal Surgery Study (CLASS)-01. However, studies focusing on use of LDG older than 65 years are rare. This study was designed to investigate morbidity and mortality elderly who underwent laparoscopic-assisted or open (ODG). In this...
<b><i>Background:</i></b> The prognosis of stage III gastric cancer (GC) patients based on the 8th edition TNM staging system after D2 dissection was still heterogeneous. We aimed to explore clinicopathological reasons that led poor these patients, especially from a surgical aspect. <b><i>Methods:</i></b> divided 320 GC who underwent distal or total gastrectomy with lymphadenectomy into group 1 and 2, according disease-free survival (DFS),...
Lung cancer is one of the most common malignant tumors in world, and its lethality ranks first among many tumors. For non-small cell lung (NSCLC) patients, due to high mortality rate, overall 5-year survival rate less than 15%. When NSCLC undergoes local invasion, only 20%, it even lower when distant metastasis occurs up 4%. Almonertinib an innovative drug independently researched developed by China with independent intellectual property rights. As epidermal growth factor receptor tyrosine...
<sec><b>Objective</b>As laparoscopic surgery is widely applied for primarily treated gastric cancer (GC)/gastroesophageal junction (GEJC) and gains many advantages, the feasibility of total gastrectomy (LTG) GC/GEJC patients who have received preoperative therapy (PT) has come to fore. This study aims analyze safety LTG after PT patients. </sec><sec><b>Methods</b>We retrospectively analyzed data 511 with undergoing LTG, which 405 (LTG group) 106 PT+LTG (PT-LTG at Nanfang Hospital between...