- Membrane Separation Technologies
- Membrane-based Ion Separation Techniques
- Advanced biosensing and bioanalysis techniques
- Lung Cancer Treatments and Mutations
- Thyroid Cancer Diagnosis and Treatment
- MXene and MAX Phase Materials
- Reproductive Biology and Fertility
- Advanced battery technologies research
- Reconstructive Surgery and Microvascular Techniques
- Cytokine Signaling Pathways and Interactions
- Cancer-related molecular mechanisms research
- Nanopore and Nanochannel Transport Studies
- Lung Cancer Research Studies
- Hemoglobinopathies and Related Disorders
- Toxoplasma gondii Research Studies
- Cancer-related Molecular Pathways
- Blood groups and transfusion
- Ovarian function and disorders
- Ferrocene Chemistry and Applications
- Nanoplatforms for cancer theranostics
- FOXO transcription factor regulation
- Breast Implant and Reconstruction
- Cancer Genomics and Diagnostics
- Reproductive Health and Technologies
- Cancer-related gene regulation
Guangzhou Medical University
2020-2025
Xuzhou Medical College
2023-2025
Chengdu University of Technology
2023-2024
Nanjing Medical University
2023
Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
2019
Wenzhou Medical University
2018-2019
Affiliated Hospital of Guangdong Medical College Hospital
2018
Guangdong Medical College
2018
Hunan Normal University
2010
Abstract T‐cell‐based immunotherapy holds promise for eliminating cancer through T‐cell activation. However, prolonged interaction between T cells and tumors the presence of immunosuppressive factors can diminish cytotoxicity, leading to treatment failure. Here, ribonuclease 1 (RNase1), which degrades RNA, reduced expression effector cytokines increases immune checkpoint protein levels, inducing dysfunction. RNase1 is positively associated with exhausted gene signatures proteins across...
The aim of this retrospective study was to examine how a low estradiol/follicle (E2/fol) may be related in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI)-embryo transfer outcomes polycystic ovary syndrome (PCOS) and non-PCOS patients, respectively. Between 2013 2017, 516 IVF/ICSI cycles (146 PCOS patients 370 patients) with long gonadotrophin releasing hormone receptor agonist protocol—including 338 involved fresh (89 249 patients)—were conducted. Outcomes were compared...
Objective To explored the risk factors of lymph node metastasis in papillary thyroid microcarcinoma (PTMC) by analyzing data from Surveillance,Epidemiology and End Results (SEER) database.Methods The 31 017 patients with PTMC SEER database 2002 to 2012 were retrospectively analyzed. Logistic Cox regression analyses used explore associations PTMC.Results Multivariate analysis revealed that male (OR=0.673,95%CI=0.605-0.748,P=0.001),age<55 years (OR=0.683,95%CI =0.623-0.749,P=0.001),tumor size...
With the application of nanomaterials in seawater desalination technology increasing, adjustable characteristics carbon-based make it possible to use multiwalled carbon nanotube (MWCNT) materials technology. In this study, Ni[Fe(CN)6]2 is loaded onto inner wall MWCNTs by co-precipitation method prepare with variable pore size, making a switchable cage for NaCl. During procedure, most transferred outer surface after adsorption, and NaCl stored inside (which have been proved characterization);...
Abstract In the multicenter, dose-escalation and dose-expansion phase 1 clinical trial (NCT05767866), we evaluated safety tolerability of YK-029A in various EGFR mutated non-small-cell lung cancer (NSCLC). We have reported efficacy untreated NSCLC with ex20ins mutation[1]. This time report patients acquired T790M mutation after failure first or second generation tyrosine kinase inhibitors (TKIs). Method: recruited previously treated rare mutations. phase, were enrolled. was given at doses...
Cancer incidence and mortality are rapidly growing around the world. As a noninvasive strategy for cancer treatment, photothermal therapy (PTT) utilizes near-infrared (NIR) light absorbents to produce local hyperpyrexia from energy, resulting in thermal elimination of tumors. Different nanostructures that possess strong absorbance NIR have been exploited as agents (PTAs) need be biodegradable optical window. However, it remains highly challenging identify small molecule-based with high...
Widely recognized as an essential epitranscriptomic modification, RNA N6-methyladenosine (m6A) is involved in both physiological and pathological processes. Here, we want to investigate m6A modificationâs potential roles gastric cancer. Gastric cancer samples were selected from TCGA-STAD GEO (GSE84426, GSE84433) datasets. Based on 18 regulators of m6A, modification patterns thoroughly evaluated samples. Principal component analysis algorithms used construct the m6Ascore, using which,...