Xiaojian Chen

ORCID: 0000-0003-1579-0706
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About
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Research Areas
  • Cervical Cancer and HPV Research
  • Advanced Radiotherapy Techniques
  • Global Cancer Incidence and Screening
  • Ferroptosis and cancer prognosis
  • Hepatitis B Virus Studies
  • Radiomics and Machine Learning in Medical Imaging
  • Reproductive tract infections research
  • Radio Frequency Integrated Circuit Design
  • Breast Cancer Treatment Studies
  • Molecular Biology Techniques and Applications
  • Contact Dermatitis and Allergies
  • Pancreatic and Hepatic Oncology Research
  • Allergic Rhinitis and Sensitization
  • Genital Health and Disease
  • Anesthesia and Sedative Agents
  • Epigenetics and DNA Methylation
  • Head and Neck Cancer Studies
  • GaN-based semiconductor devices and materials
  • Respiratory viral infections research
  • Acoustic Wave Resonator Technologies
  • Pneumonia and Respiratory Infections
  • Immune cells in cancer
  • Medical Imaging Techniques and Applications
  • Drug-Induced Adverse Reactions
  • Toxoplasma gondii Research Studies

Wenzhou Medical University
2004-2024

Sun Yat-sen University
2007-2023

Command Hospital
2023

National Cancer Institute
2020-2022

Division of Cancer Epidemiology and Genetics
2020-2022

Suzhou Municipal Hospital
2014-2022

Nanjing Medical University
2014-2022

University of Benin
2022

Medical College of Wisconsin
2014-2021

Tongji Hospital
2021

The 2019 American Society for Colposcopy and Cervical Pathology Risk-Based Management Consensus Guidelines the management of cervical cancer screening abnormalities recommend 1 6 clinical actions (treatment, optional treatment or colposcopy/biopsy, 1-year surveillance, 3-year 5-year return to regular screening) based on risk intraepithelial neoplasia grade 3, adenocarcinoma in situ, (CIN 3+) many different combinations current recent past results. This article supports main guidelines...

10.1097/lgt.0000000000000529 article EN cc-by-nc-nd Journal of Lower Genital Tract Disease 2020-04-01

HPV testing is replacing cytology for cervical cancer screening because of greater sensitivity and superior reassurance following negative tests the dozen genotypes that cause cancer. Management women positive unresolved. The need identification individual clinical use debated. Also, it unclear how long to observe persistent infections when precancer not initially found.

10.1016/j.eclinm.2020.100293 article EN cc-by-nc-nd EClinicalMedicine 2020-04-25

Objective To manage cervical screening abnormalities, the 2019 ASCCP management consensus guidelines will recommend clinical action on basis of risk precancer and cancer. This article details methods used to estimate risk, determine risk-based management, validate that recommendations are general use in different settings. Methods Based 1.5 million patients undergoing triennial by cotesting at Kaiser Permanente Northern California from 2003 2017, we estimated profiles for scenarios...

10.1097/lgt.0000000000000528 article EN cc-by-nc-nd Journal of Lower Genital Tract Disease 2020-04-01

In an effort for early assessment of treatment response, we investigate radiation induced changes in quantitative CT features tumor during the delivery chemoradiation therapy (CRT) pancreatic cancer.Diagnostic-quality data acquired daily routine CT-guided CRT using a CT-on-rails 20 head cancer patients were analyzed. On each CT, head, spinal cord and aorta delineated histograms number (CTN) these contours extracted. Eight histogram-based radiomic metrics including mean CTN (MCTN), peak...

10.1371/journal.pone.0178961 article EN cc-by PLoS ONE 2017-06-02

Mycoplasma pneumoniae is a major pathogen causing community-acquired (CAP), which generally treated with macrolides. In recent years, however, although macrolide-resistant M. has been reported frequently, particularly in China, very little known about the prevalence of infection adults. this study, we survey adults Zhejiang province and characterize mechanisms resistance to macrolide. Six hundred fifty throat swab samples were collected from adult patients CAP January 2012 August 2014. These...

10.1128/aac.04308-14 article EN Antimicrobial Agents and Chemotherapy 2014-12-02

HPV35 has been found in only ∼2% of invasive cervical cancers (ICC) worldwide but up to 10% Sub-Saharan Africa, warranting further investigation and consideration impact on preventive strategies. We studied ethnicity, relation the known steps carcinogenesis, using multiple large epidemiologic studies U.S. internationally. Combining five studies, we measured positivity and, Northern California, observed type-specific population prevalence estimated 5-year risk developing precancer when...

10.1002/ijc.33033 article EN International Journal of Cancer 2020-05-04

The 2019 ASCCP Risk-Based Management Consensus Guidelines include recommendations for partial human papillomavirus (HPV) genotyping in management of abnormal cervical cancer screening results. guidelines are based on matching estimates intraepithelial neoplasia (CIN) 3+ risk to consensus clinical action thresholds. In support the guidelines, this analysis addresses risks predicted by individual identification HPV 16 and 18.Risk were drawn from a subset women Kaiser Permanente Northern...

10.1097/lgt.0000000000000530 article EN cc-by-nc-nd Journal of Lower Genital Tract Disease 2020-04-01

The morphology and properties of corn starch cassava were compared by SEM, DSC TGA. effects amylose amylopectin content on studied FT-IR, XRD XPS. plywood was presse... | Find, read cite all the research you need Tech Science Press

10.32604/jrm.2021.014751 article EN cc-by JOURNAL OF RENEWABLE MATERIALS 2021-01-01

Objective The US screening and management guidelines for cervical cancer are based on the absolute risk of precancer estimated from large clinical cohorts trials. Given widespread transition toward with human papillomavirus (HPV) testing, it is important to assess which additional factors include in assessment optimize HPV-infected women. Materials Methods We analyzed data women, ages 30–65 years, National Cancer Institute–Kaiser Permanente Northern California Persistence Progression study....

10.1097/lgt.0000000000000667 article EN Journal of Lower Genital Tract Disease 2022-03-07

The preparation principle and the result interpretation of COVID-19 antibody rapid detection strip.

10.1039/d0ra04107f article EN cc-by-nc RSC Advances 2020-01-01

A monolithic AlGaN/GaN HEMT voltage-controlled oscillator (VCO) using a barium-strontium-titanate (BST) thin-film varactor is presented. The fabrication process of the VCO fully compatible with standard GaN microwave integrated circuits (MMICs). An improved equivalent circuit model fabricated BST for application was developed MMIC design. experiment exhibits 1-GHz tunable bandwidth at central frequency 7 GHz when bias changed from 0 to 24 V. output power 17 dBm and phase noise -81 dBc/Hz (at...

10.1109/tmtt.2012.2209442 article EN IEEE Transactions on Microwave Theory and Techniques 2012-08-13

Introduction: Mycoplasma pneumoniae (M. pneumoniae) is the most common atypical pathogen that causes respiratory infections in humans. Laboratory tests are important diagnosis of M. because features clinical signs and symptoms. Nowadays, both P1 adhesin gene 16S ribosomal (r) RNA (rRNA) have been widely detected by polymerase chain reaction (PCR). The purpose present study was to evaluate suitable target detection pneumonia via nested PCR. Methodology: Both rRNA for PCR conditions were...

10.3855/jidc.5149 article EN cc-by The Journal of Infection in Developing Countries 2015-03-15

Abstract Necessary stages of cervical carcinogenesis include acquisition a carcinogenic human papillomavirus (HPV) type, persistence associated with the development precancerous lesions, and invasion. Using prospective data from immunocompetent women in Guanacaste HPV Natural History Study (NHS), ASCUS‐LSIL Triage (ALTS) Costa Rica Vaccine Trial (CVT), we compared early natural history types to inform transition probabilities for health decision models. We excluded evidence high‐grade...

10.1002/ijc.34128 article EN International Journal of Cancer 2022-05-23

Abstract Background Platelets play a role in tumor cell growth, metastasis, and angiogenesis, the present study aimed to evaluate diagnostic prognostic values of platelet parameters patients with gynecological tumors. Methods A total 1062 women were included. Differences (platelet count [PLT], plateletcrit [PCT], mean volume [MPV], platelet‐large rate [P‐LCR], distribution width [PDW]) between different categories analyzed by nonparametric test. The optimal cutoff value was calculated...

10.1002/jcla.23295 article EN cc-by Journal of Clinical Laboratory Analysis 2020-03-13

Psoriasis is chronic incurable skin inflammation. The anti-inflammatory properties of mesenchymal stem cells (MSCs) have been put forward to be involved in several inflammatory diseases. However, little was known about the role human adipose tissue-derived (hAD-MSCs) psoriasis.We sought explore feasibility using hAD-MSCs infusion as a therapeutic approach psoriatic mice.We constructed psoriasis-like model by IMQ implication, treated with subcutaneous injection. To evaluate efficacy, we...

10.1080/09546634.2021.1925622 article EN Journal of Dermatological Treatment 2021-06-01

Abstract Purpose This study aimed to investigate the relevance of cerebral endothelial cell adhesion molecule (CERCAM) expression head and neck squamous carcinoma (HNSCC) prognosis immune infiltration by macrophage M2 polarization. Methods Timer, UALCAN HPA databases was used analyze differences in mRNA protein levels CERCAM HNSCC. The Timer database also applied correlation between HNSCC infiltration. TCGA-HNSCC clinicopathological features, its diagnostic prognostic value assessed....

10.1186/s12903-023-03421-0 article EN cc-by BMC Oral Health 2023-10-07
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