A5020786580- Glycosylation and Glycoproteins Research
- Luminescence and Fluorescent Materials
- Nanopore and Nanochannel Transport Studies
- Crystallization and Solubility Studies
- Advanced biosensing and bioanalysis techniques
- Microfluidic and Capillary Electrophoresis Applications
- Monoclonal and Polyclonal Antibodies Research
- Covalent Organic Framework Applications
- X-ray Diffraction in Crystallography
- Molecular Sensors and Ion Detection
- Carbohydrate Chemistry and Synthesis
- Chemical and Physical Properties in Aqueous Solutions
- Nanoplatforms for cancer theranostics
- Proteoglycans and glycosaminoglycans research
- Advanced Nanomaterials in Catalysis
- Advanced Cellulose Research Studies
- Click Chemistry and Applications
- Biosensors and Analytical Detection
- Influenza Virus Research Studies
- Supramolecular Self-Assembly in Materials
- Extraction and Separation Processes
- Advanced Synthetic Organic Chemistry
- Sulfur-Based Synthesis Techniques
- Crystallography and molecular interactions
- Wastewater Treatment and Nitrogen Removal
Dalian Jiaotong University
2024
Tianjin University of Science and Technology
2015-2024
Tianjin Economic-Technological Development Area
2020-2023
Dalian Institute of Chemical Physics
2023
Chinese Academy of Sciences
2023
Dalian Polytechnic University
2023
Pathogenic bacteria are widely distributed in diverse environments and significantly threaten human health. Point-of-care testing (POCT) is a valuable way for early warnings of threat. Herein, chemiluminescence (CL)-based ratiometric sensing platform was constructed sensitive POCT according to newly designed aggregation-induced emission (AIE) molecule. The new AIE molecule presents oxidase-like properties (named as AIEzyme) can trigger long persistent CL luminol (LUM) with strong intensity...
Abstract Boroxines are significant structures in the production of covalent organic frameworks, anion receptors, self-healing materials, and others. However, their utilization aqueous media is a formidable task due to hydrolytic instability. Here we report water-stable boroxine structure discovered from 2-hydroxyphenylboronic acid. We find that, under ambient environments, acid undergoes spontaneous dehydration form dimer with dynamic bonds aggregation-induced enhanced emission activity....
Tyrosine phosphorylation (pTyr), much of which occurred on localized multiple sites, initiates cellular signaling, governs functions, and its dysregulation is implicated in many diseases, especially cancers. pTyr-specific sensing great significance for understanding disease states developing targeted anticancer drugs, however, it very challenging due to the slight difference from serine (pSer) or threonine (pThr). Here we present polyethylenimine-g-phenylguanidine (PEI-PG)-modified...
The aberrant expression of sialylated glycans (SGs) is closely associated with the occurrence, progression, and metastasis various cancers, glycoproteins have been widely used as clinical biomarkers for cancers. However, identification comprehensive analysis SGs are exceptionally complex, which urgently need an innovative effective method capturing from biosamples prior to MS analysis. Here, we report that a novel dynamic covalent chemistry strategy based on Schiff base hydrolysis can be...
Abstract Targeted killing multidrug‐resistant bacteria with high efficiency is urgently needed for the treatment of infection minimal collateral damage. Herein, a new near‐infrared (NIR) fluorescence nanoprobe designed and synthesized aggregation‐induced emission (AIE) features, which also excellent reactive oxygen species (ROS) generator. The as‐prepared AIE nanoparticles (NPs) present outstanding sterilizing rate on methicillin‐resistant Staphylococcus aureus (MRSA) kanamycin‐resistant...
A glycan-responsive polymer-modified nanochannels system enables the precise discrimination of sialylated glycan linkage isomers <italic>via</italic> different “OFF–ON” changes resulting from a “tug-of-war” between polymer-glycan binding and polymer shrinkage.
An efficient method of α-keto amides to α-hydroxy has been developed for the regioselective hydrogenation reduction. Under assistance electricity and methanol as both hydrogen source solvent,...
Excitation wavelength-dependent (Ex-De) chromophores, which exhibit changes in spectral composition with varying excitation wavelengths, have garnered significant interest. However, the pursuit of novel photoluminescence (PL) mechainsims and high luminescence quantum...
Biological photonic nanostructures comprising a hierarchically self-assembled cellulose nanocrystal (CNC) have been exploited for the development of sensing, optoelectronics, and energy materials. Although multiple techniques are used controlling optical response chiral nematic structure CNC-derived materials, presence external studies that pristine CNC has chemoselectivity is not yet reported to implement this destination. Here, we report film without modification shows high sensitivity...
Saccharides are involved in nearly all life processes. However, due to the complexity and diversity of saccharide structures, their selective recognition is one most challenging tasks. Distinct from conventional receptor designs that rely on delicate complicated molecular here a novel precise ternary co-assembled strategy reported for achieving recognition, which originates halogen ions-driven aggregation-induced emission module called p-Toluidine, N, N'-1-propen-1-yl-3-ylidene hydrochloride...
Molecular configuration strongly impacts on its functions; however, due to complicated and diverse as well easy rapid conversion among various configurations, research of molecular is extremely difficult. If the free rotation a molecule could be "slowed down" or even "frozen" by an external stimulus, such ultralow temperature, then one captured characterized relatively easily. Here, we show that hemicyanine-labeled 2-(2'-hydroxyphenyl)-4-methyloxazole (H-HPMO) specifically reversibly...
A remarkable inhibition effect and chiral discrimination are observed when the amyloid peptide aggregates on phospholipid surfaces.
Discerning tyrosine phosphorylation (pTyr) catalyzed by Tyr kinase is central to the revelation of oncogenic mechanisms and development targeted anticancer drugs. Despite some techniques, this goal remains challenging, especially when faced with interference multiple events, including serine (pSer) threonine (pThr). We describe here a functional polymer-modified artificial ion nanochannel, which enables sensitive selective recognition phosphotyrosine (pY) peptide distinct ionic current...
Access to clean and renewable energy, osmotic energy from salinity gradient difference, for example, is central the sustainability of human civilization. Despite numerous examples nanofluidic membranes conversion, one produced abundant biomass resources remains largely unexplored. In this work, cotton-derived cellulose nanocrystals (CNCs) are employed fabricate a membrane by self-assembly with polyvinyl alcohol (PVA) subsequent in situ growth metal-organic framework (MOF), UiO-66-(COOH)