A Rodríguez
A5112239539- Inflammatory Bowel Disease
- Parkinson's Disease Mechanisms and Treatments
- Microscopic Colitis
- RNA regulation and disease
- Neurological diseases and metabolism
- Genetic Associations and Epidemiology
- Endometriosis Research and Treatment
- Eosinophilic Esophagitis
- Astronomical Observations and Instrumentation
- Historical Art and Architecture Studies
- Rheumatoid Arthritis Research and Therapies
- Celiac Disease Research and Management
- Libraries, Manuscripts, and Books
- Pregnancy and Medication Impact
- Adaptive optics and wavefront sensing
- Appendicitis Diagnosis and Management
- Monoclonal and Polyclonal Antibodies Research
- Spanish Literature and Culture Studies
- Biosimilars and Bioanalytical Methods
- Diverticular Disease and Complications
- Inertial Sensor and Navigation
- Intraperitoneal and Appendiceal Malignancies
- Brucella: diagnosis, epidemiology, treatment
- Reproductive System and Pregnancy
- Abdominal Trauma and Injuries
Hospital de Referencia La Equina
2024
Hospital General Universitario de Alicante Doctor Balmis
2020-2023
Instituto de Investigación Marqués de Valdecilla
2019-2021
Complejo Hospitalario de Salamanca
1999-2021
Genomics England
2021
Marqués de Valdecilla University Hospital
2019-2021
Universidad de Cantabria
2019-2020
Universidad de Granada
2020
Universidad de Salamanca
2019
Biomedical Research Networking Center on Neurodegenerative Diseases
2019
The Iberian Peninsula stands out as having variable levels of population admixture and isolation, making Spain an interesting setting for studying the genetic architecture neurodegenerative diseases.
In July 2024, Sunrise completed its third successful science flight. The III observatory had been upgraded significantly after the two previous flights in 2009 and 2013. Three completely new instruments focus on small-scale physical processes their complex interaction from deepest observable layers photosphere up to chromospheric heights. Previously poorly explored spectral regions lines are exploited paint a three-dimensional picture of solar atmosphere with unprecedented completeness level...
To investigate the occurrence of anti-annexin V autoantibodies in sera patients with rheumatoid arthritis to assess involvement disease and any relation glucocorticoid treatment. Anti-annexin antibodies were measured by an enzyme linked immunosorbent assay (ELISA) which used purified human recombinant protein as antigen. Concentrations autoantibodies, predominantly IgG class, significantly raised from compared normal controls. This was not correlated other indices activity such erythrocyte...
Thiopurines are the most widely used immunosuppressants in inflammatory bowel disease (IBD). However, patients using these drugs present drug-related adverse effects (AE) 20–30% of cases. In a previous study, we observed different profile thiopurine-related AE elderly-onset IBD. On other hand, use biological agents elderly could be associated with an increased risk infections, so they not clear alternative. Our aim was to evaluate safety thiopurines IBD according age initiation treatment....
The purpose of this review is to conduct an analysis the results using current methods treatment patients with generalized peritonitis applying laparostomy technique («open abdomen») and assess prospects for its development. General considerations. There are currently no generally accepted satisfactory surgeons in peritonitis. systematic reviews often difficult interpret due combination studies without control groups, as well dif ferent methodologies used analyze results. use has many...
ABSTRACT Background The Iberian Peninsula stands out as having variable levels of population admixture and isolation, making Spain an interesting setting for studying the genetic architecture neurodegenerative diseases. Objectives To perform largest Parkinson disease (PD) genome-wide association study (GWAS) restricted to a single country. Methods We performed GWAS both risk PD age-at-onset (AAO) in 7,849 Spanish individuals. Further analyses included population-specific haplotype...
Abstract Background Evidence regarding vedolizumab (VDZ) influence on extraintestinal manifestations (EIMs) in inflammatory bowel disease patients (IBD) is scarce. Our aim was to analyze the effectiveness of VDZ pre-existing EIMs and occurrence de novo during therapy IBD. Methods We performed an observational, multicenter, retrospective cohort study including from Spanish ENEIDA registry promoted by GETECCU. retrospectively identified 551 20 centers. The co-primary outcomes were evaluate...
In this work, the optical measurement system employed to evaluate performance of a 6 degrees freedom (dof) positioning mechanism under cryogenic conditions is explored. The mechanism, flight model three translations and rotations was developed by Spanish company SENER (for ASTRIUM) fulfil high requirements from ESA technology preparatory program for secondary mirror within GAIA Astrometric Mission. Its has been evaluated vacuum temperature controlled (up 10<sup>-6</sup>mbar 100K) at...
Background Headache is a frequent symptom at the onset of Listeria meningitis, accompanied by others such as fever, altered mental status and meningeal signs, but never reported so far an isolated symptom. Methods Results Two immunocompetent males, with no history primary headaches, went to emergency department because headache. The first after sudden severe, holocranial headache without other associated symptoms, second subacute, moderate oppressive in temples, which 8 days later added mild...
The aims of this study were (1) to assess the effectiveness VDZ in IBD patients and (2) identify factors associated with response treatment. [Crohn’s disease (CD) ulcerative colitis (UC)] that had received at least 3-induction doses ENEIDA registry—a large prospectively maintained Spanish database promoted by Working Group Crohn’s Colitis (GETECCU) included. Patients treated due active [Partial Mayo Score (PMS) ≥2 or Harvey-Bradshaw (HBI) >4] Short-term was evaluated week 14. Clinical...
The long-term benefit of VDZ in IBD patients clinical practice is almost unknown. aims this study were (i) to assess the overall durability response who initially responded induction doses; (ii) identify predictive factors for loosing treatment; and (iii) safety practice. [Crohn’s disease (CD) ulcerative colitis (UC)] that had received at least three doses with ENEIDA registry, a large prospectively maintained Spanish database promoted by GETECCU, included. Patients inactive initiation...
Infliximab is one of the most used biological drugs in inflammatory bowel disease (IBD). Immunomediated adverse events (IAE) are frequent reported infliximab-related events. Elderly patients have differential pharmacodynamic and pharmacokinetic characteristics. We recently an increased risk thiopurine-related AEs this population; hence, it would be relevant to ascertain if combined treatment adequate population. Our aim was evaluate rate IAE elderly IBD patients. All adult ENEIDA registry (a...
Abstract Background Inflammatory bowel disease (IBD) commonly affects women and men during the reproductive years.The effect of burden on fertility in these patients is a common concern for them. ECCO guidelines establish that active associated with decreased but studies regarding this topic are low quality outdated. Aims to investigate CD fertility, studying ovarian reserve as well global Sertoli cell function men, - To compare results healthy control group. (HC) assess related factors...
IACATS is an atmospheric turbulence, stars and telescope simulator for the evaluation of on ground telescopes instrumentation developed by INTA (optics) LIDAX (opto-mechanics) IAC (Instituto de Astrofísica Canarias). Three have been simulated, matching f number, focal plane, optical interface actual telescopes. An breadboard was designed built containing required opto-mechanics simulating telescopes, various levels turbulence required. In addition to optics, a set three phase plates procured...
IMaX current status is reported on. IMaX, the Imaging Magnetograph eXperiment developed for a Spanish consortium SUNRISE Mission, payload that will work simultaneously as high sensitivity polarimeter, resolving spectral power, and near diffraction limited imager. Once every mechanical element has been purchased, assembly, integration, alignment verification processes (AIV process) carried out successfully. After brief description of opto-mechanical elements have received, integration...