A5081042872- Adipokines, Inflammation, and Metabolic Diseases
- Stress Responses and Cortisol
- Cardiovascular Disease and Adiposity
- Blood Pressure and Hypertension Studies
- Acute Myocardial Infarction Research
- Adipose Tissue and Metabolism
- Exercise and Physiological Responses
- Cardiac Health and Mental Health
- Hormonal Regulation and Hypertension
- Adrenal Hormones and Disorders
- Heart Rate Variability and Autonomic Control
- Health and Lifestyle Studies
- Protease and Inhibitor Mechanisms
- Bacterial Infections and Vaccines
- COVID-19 Clinical Research Studies
- Lipoproteins and Cardiovascular Health
- Tracheal and airway disorders
- Reproductive biology and impacts on aquatic species
- Cardiovascular Function and Risk Factors
- Cancer, Lipids, and Metabolism
- Heart Failure Treatment and Management
- Aquaculture Nutrition and Growth
- Cardiovascular Health and Disease Prevention
- Nitric Oxide and Endothelin Effects
- Dermatology and Skin Diseases
University of Buenos Aires
2012-2025
Instituto de Química y Fisicoquímica Biológicas
2025
University of Freiburg
2019
Abstract We present the development of first procedure for hair cortisol measurement through an automated method. Hair samples were obtained from 286 individuals. After extraction, measured in a Siemens Immulite 2000 (Gwynedd, UK) chemoluminiscent immunoassay analyzer. Normal reference values levels 213 healthy individuals with low stress. concentration median was 55 pg/mg (2.5–97.5 percentile (40–128)) stress and 250 (range 182–520) stressed No significant differences observed between...
Abstract Background: Chronic and psychosocial stress are emerging factors linked to cardiovascular disease. Assessment of cortisol levels in hair can serve as an indicator individual’s exposure prolonged stressful events. For its evaluation, mass spectrometry is the reference method. However, because limitations for clinical laboratories, automated chemiluminescent method was developed our laboratory. The objective study evaluate measured by association with cardiometabolic risk a Latin...
Psychological factors and stressful life events (LE) are considered to play a role in the onset of metabolic syndrome (MS). We tested association between LE cortisol, marker chronic stress, with risk developing MS their interaction. From total number 2906 men who completed screening for early detection prostate cancer, 149 healthy (mean ± SD age, 58.6 7.7 years) were included this study. Participants assessed by Holmes Rahe questionnaire about experience during previous 1–5 years. was...
Background Metalloproteinases (MMPs) are synthesized in the subendothelium and involved atherosclerosis cardiovascular disease process because of their major significance vascular remodeling plaque rupture. MMPs also adipose tissue during angiogenesis; however, role these enzymes obesity insulin-resistant states is still controversial.Objective To evaluate MMP-2 activity circulation overweight obese women normal-weight controls, to associate levels factors with metabolic, inflammation...
Abstract Background Matrix metalloproteinases ( MMP s), especially ‐2 and ‐9, have been identified in atherosclerotic plaques directly associated with plaque remodelling vulnerability. Cardiovascular disease (CVD) is related to insulin resistance IR ) obesity, characterized by changes plasma levels of inflammatory markers, such as adiponectin C‐reactive protein CRP ). Our aim was evaluate the impact both proteins on ‐9 behaviour individuals . Materials methods Plasma activity, hs‐...
Vitamin D is a fat soluble vitamin involved in calcium and bone metabolism; recently its deficiency has been related to cardiovascular disease. In cardiac tissue, suppresses metalloproteinases (MMPs) expression, enzymes directly associated with vulnerable plaque.To investigate whether the association between leptin markers of plaque, such as MMPs patients acute myocardial infarction.We studied 66 male infarction, undergoing primary angioplasty. Blood samples were obtained at admission 24hs...
Previous studies have tested the relationship between chronic stress and sex hormones, but inconsistent results been found. One possibility is that this association may depend on other biological factors. This study examined stressful life events (LE) hormones in men, whether cortisol involved relationship. From a total number of 2906 men who completed screening for early detection prostate cancer, 139 healthy (mean ± SD age, 57.8 5.7 years) were included study. Participants assessed with...
Coronavirus disease-19 (COVID-19) patients with severe complications present comorbidities like cardiovascular-disease, hypertension and type-2 diabetes mellitus (DM), sharing metabolic alterations insulin resistance (IR) dyslipidemia. Our objective was to evaluate the association among different components of lipid-lipoprotein profile, such as remnant lipoprotein (RLP)-cholesterol, in COVID-19, analyze their associations severity disease death. We studied 193 (68 (29-96) years; 49.7% male)...
Introducción: la meningitis bacteriana postneuroquirúrgica (MBPN) presenta alta mortalidad. El diagnóstico rápido es esencial. método de referencia el cultivo del líquido cefalorraquídeo (LCR), pero requiere tiempo, utilizándose antibióticos empíricos innecesarios, importante evaluar otros parámetros que permitan una detección temprana. Objetivos: utilidad lactato en LCR como marcador temprano MBPN, determinar su punto corte nuestra población y correlacionar valores con proteinorraquia...
Abstract Introduction Many clinical and experimental observations have established an association between visceral obesity chronic adipose tissue inflammation. Potent pro-inflammatory mediators such as TNFα, CD40 IL-1β are regulated by Tumor necrosis factor (TNF) receptor-associated factors (TRAFs). TRAF5 deficiency accelerates atherogenesis in mice increasing inflammatory leukocyte recruitment. Since cell invasion is also a prerequisite of inflammation, we tested the hypothesis that...