A5104181561- Intracranial Aneurysms: Treatment and Complications
- Cerebrovascular and Carotid Artery Diseases
- Vascular Malformations Diagnosis and Treatment
- Traumatic Brain Injury and Neurovascular Disturbances
- Moyamoya disease diagnosis and treatment
- Cardiovascular Disease and Adiposity
- Spinal Fractures and Fixation Techniques
- Lung Cancer Diagnosis and Treatment
- Plant Disease Resistance and Genetics
- Aortic Disease and Treatment Approaches
- T-cell and B-cell Immunology
- Acute Lymphoblastic Leukemia research
- Sepsis Diagnosis and Treatment
- Mechanical Circulatory Support Devices
- Hemodynamic Monitoring and Therapy
- Pregnancy and Medication Impact
- Cystic Fibrosis Research Advances
- Cardiovascular and Diving-Related Complications
- Epigenetics and DNA Methylation
- Heparin-Induced Thrombocytopenia and Thrombosis
- Lung Cancer Treatments and Mutations
- Infrared Target Detection Methodologies
- Aortic aneurysm repair treatments
- Nosocomial Infections in ICU
- Central Venous Catheters and Hemodialysis
Capital Medical University
2016-2024
Beijing Institute of Neurosurgery
2018-2024
Beijing Tian Tan Hospital
2016-2024
Jiading District Central Hospital
2024
Shanghai University of Medicine and Health Sciences
2024
First Affiliated Hospital of Anhui Medical University
2024
Anhui Medical University
2024
China Medical University
2024
Shanghai Maritime University
2024
Northeast Agricultural University
2024
Background: The purpose of this research was to analyze the effect morphologic and hemodynamic characteristics on mirror aneurysms in which one ruptured other did not, within same patient, identify reliable predictors rupture. Methods: We performed three-dimensional angiographic imaging 56 patients with intracranial for computational fluid dynamic studies from January 2009 December 2015. aneurysm simulations were conducted geometry obtained after significance parameters respect rupture...
Background: Characterization of the risk factors for rupture very small intracranial aneurysm (VSIA, ≤3 mm) is clinically valuable, since VSIAs are implicated in subarachnoid hemorrhage. The aim this study was to identify morphological and hemodynamic parameters that independently characterize status VSIAs. Methods: We conducted a retrospective consecutive between September 2010 February 2014 our institute. A series morphologic were evaluated using computational fluid dynamics, based on...
Background In aneurysmal subarachnoid hemorrhage patients with multiple intracranial aneurysms (aSAH-MIA patients), the risk of secondary unruptured is inconsistent. This study aimed to explore in Chinese aSAH-MIA patients. Methods The medical records and angiographic images from eight cerebrovascular centers China were retrospectively reviewed analyzed. Patients a single aneurysm (UIA) no prior aSAH used as controls. Propensity score matching (PSM) was employed balance differences age,...
To evaluate whether the presenting symptoms of VBD predict outcomes following endovascular treatment.
Background: The effects of obstructive sleep apnea (OSA) on the prognosis acute coronary syndrome (ACS) without revascularization remain unclear, so aim present study was to elucidate association OSA with subsequent cardiovascular events in ACS patients and revascularization.
Intracranial aneurysms are increasingly being treated by the placement of flow diverters; however, factors affecting outcome using diverters remain unclarified.The present study investigated 94 with pipeline embolisation device placement, and used a computational fluid dynamics method to explore influencing aneurysms.Seventy-six completely occluded 18 incompletely were analysed. Before treatment, inflow jets found in 13 (72.2%) group 34 (44.7%) (P = 0.292). After deployment device, remained...
Background and Purpose: Stability stratification of intracranial aneurysms (IAs) is crucial for individualized clinical management, especially small IAs. We aim to develop validate a nomogram based on morphological risk factors instability Methods: Six hundred fifty-eight patients with unstable ( n = 293) stable 416) IAs <7 mm were randomly divided into derivation validation cohorts. Twelve 18 aneurysm extracted. Combined important factors, clinical-morphological predictive was...
Background and purpose A large proportion of patients with unruptured intracranial aneurysm (IA) are not suitable for surgical clipping endovascular treatment. For these patients, anti-inflammatory medications worth exploring due to inflammation aneurysmal wall being a major factor in higher risk rupture. Statin has been proven reduce atherosclerosis maybe candidate. This study aimed evaluate whether atorvastatin will inflammatory the measured by signal index enhancement. Methods analysis The...
Abstract Background Primary ciliary dyskinesia (PCD) is a genetic ciliopathy characterized by dysfunction of motile cilia. Currently, approximately 50 causative genes accounting for 60%–70% all PCD cases have been identified in PCD‐affected individuals, but the etiology 30%–40% remains unknown. Methods We analyzed clinical and data two individuals who were suspected having PCD. Whole‐exome sequencing Sanger performed to identify verify variants CFAP47 . also evaluated expression real‐time...
Apple latent spherical virus (ALSV) is widely used as a virus-induced gene silencing (VIGS) vector for function genome study. However, the application of ALSV in soybean limited by resistance many varieties. In this study, genetic loci linked to resistant variety Heinong 84 was mapped high-throughput sequencing‒Bulk Segregation Analysis (HTS‒BSA) using hybrid population crossed from and susceptible Zhonghuang 13. Results showed that controlled two located on chromosome 2 11, respectively....
Objective: Flow diverter devices are increasingly used in the treatment of posterior circulation aneurysms, sometimes necessarily involving ostia side branches and perforators. The aim this study was to identify hemodynamic influence flow diverters on perforators circulation. Methods: We performed a retrospective consecutive patients treated by device for aneurysms with anterior inferior cerebellar artery or involvement. Computational fluid dynamics were discern changes after deployment...
Genetic risk factors play an important role in the pathogenesis of familial intracranial aneurysms (FIAs); however, molecular mechanisms remain largely unknown.To investigate potential FIA-causing genetic variants by rare variant interrogation and a family-based genomics approach large family with extensive multigenerational pedigree FIAs.Exome sequencing (ES) was performed dominant likely (IAs). Variants were analyzed in-house developed pipeline prioritized using various filtering...
The true posterior communicating artery (TPCoA) aneurysms are rare and endovascular treatment for such lesions is limited in literature.From January 2012 to March 2017, eight TPCoA were treated endovascularly included our present study. procedural complication outcomes assessed.Seven of (87.5%) ruptured. Stent-assisted coiling was used one case that a stent deployed via PCoA-ipsilateral P2 segment. dual-microcatheter technique case. remaining six cases by alone. One patient (12.5%) suffered...
The low-profile visualized intraluminal support (LVIS) stent has become a promising endovascular option for treating intracranial aneurysms. To achieve better treatment of aneurysms using LVIS, we developed fast virtual stenting technique use with LVIS (F-LVIS) to evaluate hemodynamic changes in the aneurysm and validate its reliability.A patient-specific was selected making comparisons between real (R-LVIS) F-LVIS. perform R-LVIS stenting, hollow phantom based on fabricated...
Abstract Objective To explore the predictive value of lipopolysaccharide-binding protein (LBP) in assessing risk death septic patients, to provide a reference for clinical work. Methods Data from 168 patients who were admitted emergency department Beijing Chaoyang Hospital September 2021 2022 retrospectively analyzed. SPSS25.0 software was used data analysis and MedCalc 22.013 applied generate receiver operating characteristics (ROC) curves. Results A total 54 included non-survival group 114...
Locally advanced cervical carcinoma (LACC) remains a significant global health challenge owing to its high recurrence rates and poor outcomes, despite current treatments. This study aimed develop comprehensive risk stratification model for LACC by integrating Cox regression competing analyses. was done improve clinical decision making. We analyzed data from 3428 patients with registered in the Surveillance, Epidemiology, End Results program diagnosed them between 2010 2015. analyses were...
To the Editor: In neurosurgery, intraoperative fluid administration is essential in maintaining appropriate systemic and cerebral perfusion pressure, oxygenation, metabolism. Meningioma resection can involve massive blood loss due to an abundant supply structures. Moreover, routine use of mannitol during meningioma may affect hemodynamic stability. Fluid overload correlated neurological, pulmonary, or gastrointestinal (GI) edema, which has unfavorable outcomes. [1] Thus, neurosurgeries,...
The purpose of this study is to evaluate the efficacy Chinese herbal ointment Qingluo San in preventing phlebitis patients with peripheral venous catheters. We conducted a single-center randomized controlled trial, which 127 eligible were assigned randomly one two groups; experimental group or control group. degrees pain intensity and measured at baseline, 24 h, 48 h 72 h. Demographic information (age, gender, body mass index) sites, catheter dwell time, hemoglobin white blood cells obtained...