- Breast Lesions and Carcinomas
- Cancer and Skin Lesions
- Peptidase Inhibition and Analysis
- Cell Adhesion Molecules Research
- Cancer-related molecular mechanisms research
- Breast Cancer Treatment Studies
- Hair Growth and Disorders
- Radiopharmaceutical Chemistry and Applications
- Extracellular vesicles in disease
- Male Breast Health Studies
- Circular RNAs in diseases
- MicroRNA in disease regulation
- Kruppel-like factors research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- RNA Research and Splicing
- Wnt/β-catenin signaling in development and cancer
- Cancer, Lipids, and Metabolism
- Cancer Treatment and Pharmacology
- Lung Cancer Treatments and Mutations
- Reproductive System and Pregnancy
- Cancer Immunotherapy and Biomarkers
- Immunotherapy and Immune Responses
- RNA modifications and cancer
- Cervical Cancer and HPV Research
- Breast Implant and Reconstruction
Qilu Hospital of Shandong University
2021-2025
Inner Mongolia Agricultural University
2022
Harbin Medical University
2006
Conventional smear cytology (CSC) is a specific method used for breast tumor diagnosis in patients with nipple discharge. However, CSC tends to miss diagnose or even misdiagnose due contaminating blood cells and other impurities. Thus, it critical develop more accurate sensitive methods clinical evaluation. Using discharge collected directly from without aspiration, we performed liquid-based (LBC) analyze 111 samples cytological evaluation the first time. Following centrifugation remove...
microRNA (miRNA) is a type of endogenous short-chain non-coding RNA with regulatory function found in eukaryotes, which involved the regulation variety cellular and biological processes. However, research on development cashmere goat secondary hair follicles still relatively scarce. In this study, small libraries mRNA 45 days, 55 65 75 days fetal skin goats were constructed, constructed sequenced using Illumina Hiseq4000, expression profiles miRNA obtained. The differentially expressed...
Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) is a expressed in variety of types. The role CEACAM1 breast cancer development and progression largely unknown. Immunohistochemical analysis was used to examine expression with long-term follow-up. level primary low or undetectable. In 65% the cases, within tumor tissue lower than that adjacent tissues. 20% negative. 28.3% equivalent detected negatively correlated patient mortality, while positively ER+/PR+. not related...
<title>Abstract</title> Conventional smear cytology (CSC) is a specific method used for breast tumor diagnosis in patients with nipple discharge. However, CSC tends to miss diagnose or even misdiagnose due contaminating blood cells and other impurities. Thus, it critical develop more accurate sensitive methods clinical evaluation. Using discharge collected directly from without aspiration, we performed liquid-based (LBC) analyze 111 samples cytological evaluation the first time. Following...
We have previously shown that microRNAs (miRNAs) in nipple discharge are potential diagnostic biomarkers. In particular, exosomes present discharge. Herein, we sought to elucidate the protective role of on miRNAs and investigate stability encapsulated under degradative conditions. A novel TTMAAlPc-RNA complex method was used measure RNase concentration colostrum Quantitative real-time polymerase chain reaction performed test exogenous synthetic (cel-lin-4-5p cel-miR-2-3p) endogenous...
The etiology of nipple discharge is often unclear, and there are few studies exploring diagnostic approaches discharge. Galactography a common method for clinical diagnosis patients with Therefore, this study aimed to evaluate the use galactography in differentiating between benign malignant lesions A retrospective 161 discharges, who were evaluated underwent surgery Qilu Hospital Shangdong University January 2018 December 2019, was conducted. Baseline characteristics obtained from their...
Abstract Background Emerging evidence shows that circular RNAs (circRNAs) play crucial parts in tumorigenesis and progression. In this work, the expression, clinical significance, function potential mechanism of circ_0075796 breast cancer were explored. Methods The expression 189 pairs tissues adjacent normal was detected by quantitative real-time PCR (qRT-PCR). Cell Counting Kit-8 (CCK-8) assay, methyl thiazolyl tetrazolium (MTT) assay colony formation conducted for cell proliferation....