A5064622028- Coronary Interventions and Diagnostics
- Research on Leishmaniasis Studies
- Trypanosoma species research and implications
- Advanced Photocatalysis Techniques
- Acute Myocardial Infarction Research
- Spine and Intervertebral Disc Pathology
- TiO2 Photocatalysis and Solar Cells
- Spinal Fractures and Fixation Techniques
- Cervical and Thoracic Myelopathy
- Advancements in Photolithography Techniques
- Acupuncture Treatment Research Studies
- Cardiac Imaging and Diagnostics
- Layered Double Hydroxides Synthesis and Applications
- Copper Interconnects and Reliability
- Toxoplasma gondii Research Studies
- Antiplatelet Therapy and Cardiovascular Diseases
- Atrial Fibrillation Management and Outcomes
- Semiconductor materials and devices
- Burkholderia infections and melioidosis
- Health Promotion and Cardiovascular Prevention
- Healthcare and Venom Research
- Peripheral Artery Disease Management
- Smoking Behavior and Cessation
- Advanced Glycation End Products research
- Electrochemical sensors and biosensors
Yunnan University
2025
Ningbo No. 2 Hospital
2022-2024
Beijing Tsinghua Chang Gung Hospital
2016-2024
Tsinghua University
2019-2024
Nankai University
2024
Capital Medical University
2013-2022
Beijing Tian Tan Hospital
2022
Chengdu University of Traditional Chinese Medicine
2021
Kunming Children's Hospital
2018-2020
Kunming Medical University
2009-2020
In eukaryotes, sphingolipids (SLs) are important membrane components and powerful signaling molecules. Leishmania, the major group of SLs is inositol phosphorylceramide (IPC), which common in yeast Trypanosomatids but absent mammals. contrast, sphingomyelin not synthesized by Leishmania abundant promastigote stage vitro, use SL metabolism as a pathway to produce ethanolamine (EtN), metabolite essential for survival differentiation from non-virulent procyclics highly virulent metacyclics. To...
Abstract Background This study was aimed to unveil micro RNA (miRNA) expression profiles in myocardial ischemia‐reperfusion (MI/R) rats and explore whether how dysregulated miRNAs were involved the initiation progression of MI/R a calcium‐dependent manner. Method Results Rat model established cardiomyocytes isolated from neonatal induced. Both miRNA messenger analyzed by Microarray. Quantitative reverse‐transcription polymerase chain reaction, immunoblotting, bioinformatics analysis,...
Objectives: Atherosclerosis is a dominant cardiovascular disease. Curcumin has protective effect on atherosclerosis. However, the mechanisms remain to be explored. Methods: was induced by feeding mice with high-fat diet (HFD) and ox-low-density lipoprotein (LDL)-induced human umbilical vein endothelial cells (HUVECs) were structured. Oil Red O staining used evaluate plaques in artery. Quantitative real-time PCR (qRT-PCR) conducted detect level of myocardial infarction associated transcript...
Abstract Background For patients with multilevel degenerative cervical myelopathy, laminectomy and posterior fusions (PCF) instrumentation are widely accepted techniques for symptom relief. However, hardware failure is not rare results in neck pain or even permanent neurological lesions. There no in-depth studies of hardware-related complications following PCF instrumentation. Methods The present study was a retrospective, single centre, observational study. Patients who underwent...
Abstract Background To find out if three-dimensional printing (3DP) off-the-shelf (OTS) prosthesis is superior to titanium mesh cages in anterior cervical corpectomy and fusion (ACCF) when treating single-segment degenerative spondylotic myelopathy (DCSM). Methods DCSM patients underwent ACCF from January 2016 2019 a single center were included. Patients divided into the 3DP group (28) TMC (23). The hospital stays, operation time, intraoperative blood loss, cost of hospitalization compared....
Red blood cell (RBC) distribution width (RDW) is known to reflect the heterogeneity of RBC volume, which may be associated with cardiovascular events or mortality after myocardial infarction. However, association between RDW and stroke, especially regarding endpoints such as death, remains ambiguous. This study aimed explore prognostic value its effect on among patients acute ischemic stroke (AIS) undergoing intravenous thrombolysis (IVT) one year.We retrospectively reviewed AIS treated IVT...
In this study, a highly sensitive and selective sensor based on poly (3,4-ethylenedioxy- thiophene) (PEDOT) β-cyclodextrin functionalized single-walled carbon nanotubes (β-CD-SWCNT) composite was fabricated for the simultaneous determination of folic acid (FA) uric (UA) under coexistence ascorbic (AA). The modified electrode combined features PEDOT SWCNT, which hold excellent conductivity, low cost high surface areas working as an efficient electron-mediator FA UA in presence AA....
It is formerly conducted that long non-coding RNA growth arrest-specific 5 (GAS5) involved in the process of coronary atherosclerosis (AS). The regulatory effects GAS5 on microRNA (miR)-194-3p/thioredoxin-interacting protein (TXNIP) axis AS have been insufficiently explored yet. Thereafter, this work started from GAS5/miR-194-3p/TXNIP AS. rats were modeled to obtain their vascular tissues and endothelial cells (ECs), which GAS5, miR-194-3p, TXNIP expression tested. ECs identified by...
Leishmania parasites alternate between extracellular promastigotes in sandflies and intracellular amastigotes mammals. These protozoans acquire sphingolipids (SLs) through de novo synthesis (to produce inositol phosphorylceramide) salvage obtain sphingomyelin from the host). A single ISCL (Inositol phosphoSphingolipid phospholipase C-Like) enzyme is responsible for degradation of both phosphorylceramide (the IPC hydrolase or IPCase activity) SMase activity). Recent studies a L. major...
To observe the effect of pressing auricular points on myopia in children.Myopic children aged 8-9 years were divided into two groups. The Chinese herb Semen Vaccariae was used to stimulate CO10, LO5, TF4, CO15, CO12, and CO13 for three treatment courses experimental group (n = 39), while same therapy not given control 33). Binocular naked vision before after intervention measured using a standard E visual.acuity chart.There no difference binocular between intervention. In contrast, there...
Contrast-induced acute kidney injury (CI-AKI) is associated with increasing in-hospital and long-term adverse clinical outcomes in high-risk patients undergoing percutaneous coronary intervention (PCI). Contrast media (CM)-induced renal tubular cell apoptosis reported to participate this process by activating endoplasmic reticulum (ER) stress. An angiotensin II type 1 receptor (AT1R) antagonist can alleviate ER stress-induced streptozotocin (STZ)-induced diabetic mice reduce CM-induced...
To investigate whether tauroursodeoxycholic acid (TUDCA) could attenuate contrast media (CM)-induced renal tubular cell apoptosis by inhibiting endoplasmic reticulum stress (ERS), we exposed HK-2 cells to increasing doses of meglumine diatrizoate (20, 40, and 80 mg I/mL) for 2 16 hours, with/without TUDCA preconditioning 24 hours. Cell viability test, Hoechst 33258 staining, flow cytometry were used detect diatrizoate-induced apoptosis, while real-time polymerase chain reaction Western blot...