- Pain Mechanisms and Treatments
- Transcranial Magnetic Stimulation Studies
- Spinal Cord Injury Research
- Botulinum Toxin and Related Neurological Disorders
- Stroke Rehabilitation and Recovery
- Pain Management and Placebo Effect
- Long-Term Effects of COVID-19
- Musculoskeletal pain and rehabilitation
- Muscle activation and electromyography studies
- Psychosomatic Disorders and Their Treatments
- Pain Management and Treatment
- COVID-19 and Mental Health
- Nerve Injury and Rehabilitation
- Urinary Tract Infections Management
- EEG and Brain-Computer Interfaces
- Health, Environment, Cognitive Aging
- Migraine and Headache Studies
- Intensive Care Unit Cognitive Disorders
- interferon and immune responses
- Cerebral Palsy and Movement Disorders
- Pediatric Pain Management Techniques
- Nosocomial Infections in ICU
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Neural and Behavioral Psychology Studies
- Gallbladder and Bile Duct Disorders
Institut Guttmann
2013-2025
Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol
2020-2025
Universitat Autònoma de Barcelona
2013-2024
Universitat de Barcelona
2021
Texas A&M University
2015-2017
Hospital Nacional de Parapléjicos
2012-2015
Servicio de Salud de Castilla La Mancha
2012-2015
University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca
2005
Multiple and specific types of childhood adverse events are risk factors for chronic pain conditions. Although both can covary, no study has evaluated one aspect while controlling the other. Therefore, current examined whether more would be a factor common conditions medication use in young adults after different adversity such as physical, emotional, sexual traumatic or vice versa.This cross-sectional recruited 3,073 undergraduates (72% female, mean age = 18.8 years, SD 1.4 years) who...
Coronavirus disease 2019 (COVID-19) patients present long-lasting physical and neuropsychological impairment, which may require rehabilitation.The current cross-sectional study characterizes post COVID-19 sequelae persistent symptoms in an outpatient rehabilitation program.Thirty [16 post-ICU 14 non-ICU; median age = 54(43.8-62) years; 19 men] presenting and/or (>3 months after acute COVID-19) were selected of 41 referred for neurorehabilitation. Patients underwent physical, respiratory...
The contribution of endogenous pain modulation dysfunction to clinical and sensory measures neuropathic (NP) has not been fully explored. Habituation, temporal summation, heterotopic noxious conditioning stimulus-induced tonic heat intensity were examined in healthy noninjured subjects (n = 10), above the level spinal cord injury (SCI) individuals without (SCI-noNP, n 10) with NP (SCI-NP, 10). Thermoalgesic thresholds, Cz/AFz contact evoked potentials (CHEPs), phasic or (30 seconds) assessed...
This prospective, observational cohort study investigated the effects of multidisciplinary rehabilitation post Covid-19 sequelae and persistent symptoms their impact on patients' functioning quality life.From 58 patients referred for neurorehabilitation, 43 were eligible participated in present study. Before after 8 weeks rehabilitation, underwent physical, neuropsychological respiratory evaluations assessment functional independence, fatigue life.Forty individuals (52 ± 11.4 years, 24 male)...
Background Evidence in older adults suggests that higher cardiorespiratory fitness and lower cardiovascular risk are associated with greater cognition. However, given changes the brain lead to cognitive decline begin decades before onset of symptoms, understanding mechanisms by which modifiable factors health midlife is critical can development strategies promote maintain as we age. Methods Results In 501 middle-aged (aged 40-65 years) adult participants BBHI (Barcelona Brain Health...
Background: Although the spasticity syndrome is an important sensorimotor disorder, impact of grade lower limb muscle hypertonia, spasm and clonus activity on voluntary function, gait daily activities has not been systematically ana
Abstract The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed COVID-19 the SCOURGE study, we found 133 cases (1.42%) detectable clonal mosaicism for chromosome alterations (mCA) 226 (5.08%) acquired loss Y (LOY). Individuals mosaic events (mCA and/or LOY) showed a 54% increase risk...
Plasticity is one of the most important physiological mechanisms underlying motor recovery from brain lesions. Rehabilitation methods, such as mirror visual feedback therapy, which are based on multisensory integration motor, cognitive, and perceptual processes, considered effective methods to induce cortical reorganization. The present study investigated 3 different types (direct, mirrored, blocked feedback: DVF, MVF, BVF, resp.) M1 cortex excitability intracortical inhibition/facilitation...
The frequency of mitochondrial DNA haplogroups (mtDNA-HG) in humans is known to be shaped by migration and repopulation. Mounting evidence indicates that mtDNA-HG are not phenotypically neutral, selection may contribute its distribution. Haplogroup H, the most abundant Europe, improved survival sepsis. Here we developed a random forest trained model for haplogroup calling using data procured from GWAS arrays. Our results reveal context SARS-CoV-2 pandemic, HV branch were found represent...
To determine the temporal relationship between pain-related coping strategies and psychosocial factors with non-evoked neuropathic pain (NP) intensity unpleasantness in patients during subacute phase of spinal cord injury (SCI).Exploratory longitudinal study NP from 2 to 12 months.Hospital Nacional de Parapléjicos, Toledo, Spain.A maximum 26 early symptoms after SCI a neurological level above Th10 level. Multidimensional Pain Inventory-Spinal Cord Injury Version, Coping Strategies...
The current study examined pain and neurogenic inflammation responses to topical capsaicin during the interictal period (between headache) their relationship with plasma oxytocin in individuals migraine.Individuals migraine can experience generalized (extracephalic) hyperalgesia, which persist even between headache attacks. Elevated levels of cerebrospinal fluid have been observed attacks, being positively associated intensity symptoms. However, whether plays a role mechanisms sensitization...
(1) Background: Respiratory muscle weakness is common following cervical spinal cord injury (cSCI). Transcutaneous stimulation (tSCS) promotes the motor recovery of upper and lower limbs. tSCS improved breathing coughing abilities in one subject with tetraplegia. Objective: We therefore hypothesized that applied at thoracic levels could improve respiratory function cSCI subjects; (2) Methods: This study was a randomized controlled trial. Eleven subjects received inspiratory training (IMT)...
Chronic pain is associated with worse mental health and cognitive impairment, which can be a cause or consequence of brain structure function alterations, e.g., maladaptive plasticity, antinociceptive system dysregulation. Cognitive reserve reflects the effectiveness internal connections it has been shown to protective factor in damage, slowing aging reducing risk disorders. The current study explored impact chronic on psychosocial factors, health, cognition. Furthermore, we aimed examine...