A5007267898- Lignin and Wood Chemistry
- Cardiovascular and exercise physiology
- Heart Rate Variability and Autonomic Control
- Nutrition and Health in Aging
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Cardiac Health and Mental Health
- Cardiac electrophysiology and arrhythmias
- Cardiac Ischemia and Reperfusion
- Cardiovascular Disease and Adiposity
- Insect-Plant Interactions and Control
- Adipokines, Inflammation, and Metabolic Diseases
- Cardiovascular Health and Disease Prevention
- Diamond and Carbon-based Materials Research
- Blood Pressure and Hypertension Studies
- Advanced Surface Polishing Techniques
- Metal and Thin Film Mechanics
- Adipose Tissue and Metabolism
- Catalytic Processes in Materials Science
- Optimization and Variational Analysis
- Agriculture, Soil, Plant Science
- Hemodynamic Monitoring and Therapy
- Stroke Rehabilitation and Recovery
- Body Composition Measurement Techniques
- Urinary Bladder and Prostate Research
Kansai Medical University
2015-2024
Akita Prefectural University
2005-2024
Aoyama Gakuin University
2021-2023
Japan Women's College of Physical Education
2023
Tohoku University
1998-2019
Toho University
1989-2019
Tokyo Metropolitan Bokutoh Hospital
2019
Nippon Shokubai (Japan)
2018
Nissan Chemical Corporation (Japan)
2002-2017
Seikei University
2016-2017
PAD peripheral arterial disease PCI percutaneous coronary intervention peak V ˙O2 oxygen uptake PH pulmonary hypertension PVCs premature ventricular contraction QOL quality of life RCT randomized controlled trial RPE rating perceived exertion SGA Subjective Global Assessment STEMI ST elevation myocardial infarction TG triglyceride TAVI transcatheter aortic valve implantation VAD assist device ˙CO2 carbon dioxide output ˙E minute ventilation ˙E/V ventilatory equivalent for vs. slope ˙O2/HR...
Objective: The molecular mechanism of preconditioning the heart by repeated ischaemia was investigated examining expression stress related and antioxidative genes proteins. Methods: Isolated buffer-perfused rat hearts were made ischaemic for 5 min followed 10 reperfusion (1×PC). Another group experiments performed repeating ischaemia/reperfusion episode four times (4×PC). Both 1×PC 4×PC groups reperfused 60 min. Control perfusing with buffer using same time frame, but without...
Platelet-derived microparticles (PDMP) play an important role in the pathogenesis of diabetic vasculopathy, and statins or eicosapentaenoic acid (EPA) have been shown to a beneficial effect on atherosclerosis hyperlipidemic patients. However, influence EPA PDMP adiponectin is poorly understood. We investigated pitavastatin circulating levels patients with type II diabetes. A total 191 diabetes were divided into three groups: group received 2 mg once daily (n = 64), B 1800 55) C both drugs...
Non-communicable diseases (NCDs), including coronary heart disease, stroke, hypertension, type 2 diabetes, dementia, depression and cancers, are on the rise worldwide often associated with a lack of physical activity (PA). Globally, levels PA among individuals below WHO recommendations. A can increase morbidity mortality, worsen quality life economic burden society. In response to this trend, numerous organisations came together under one umbrella in Hamburg, Germany, April 2021 signed...
This study investigated the status of work-life imbalance among hospital nurses in Japan and impact on job satisfaction quality life. A cross-sectional survey 1,202 (81% response rate) was conducted three Japanese acute care hospitals. Participants were divided into four groups for actual balance (Group A: 50/50, including other lower working proportion [e.g., 40/50]; Group B: 60/40; C: 70/30; D: 80/20, higher 90/10]). We also asked participants about desired balance, private work-related...
Summary Background/Purpose Irisin is a skeletal muscle myokine that causes the brown coloration of white fat, promotes fat burning, inhibits weight gain and may be useful for treatment obesity. also related to glucose/lipid metabolism prevent onset diabetes, but consensus on irisin secretion has not been reached. The purpose this study was determine relationships between serum levels physical factors in untreated Japanese men women with Methods subjects were 66 patients obesity (body mass...
Abstract This study aimed to investigate risk factors for sarcopenia in community-dwelling older adults visiting regional medical institutions. We retrospectively analyzed records of 552 participants (mean age: 74.6 ± 6.7 years, males 31.3%) who underwent body composition evaluation between March 2017 and December 2018 at one 24 institutions belonging the Kadoma City Medical Association Japan. collected participant’s characteristics laboratory data. Sarcopenia was diagnosed according Asian...
Sarcopenic obesity is the co‐existence of and sarcopenia in individuals aged 40–75 years. The Japanese Working Group on Obesity has developed diagnostic criteria tailored for population, considering their unique characteristics compared with European populations. Our algorithm consists two steps: screening diagnosis. mandates using waist circumference and/or body mass index (BMI) based national standards, while involves “finger ring test” addition to Asian Sarcopenia 2019 criteria. final...
This paper focuses on two aspects, <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">macroscopic and microscopic</i> , of pure surfactant-added tetramethylammonium hydroxide (TMAH) wet etching. The macroscopic aspects deal with the technological/engineering applications TMAH for fabrication microelectromechanical systems (MEMS). microscopic view is focused xmlns:xlink="http://www.w3.org/1999/xlink">in situ</i> observation silicon surface during...
Irisin is a myokine implicated in lipid and glucose metabolism. The objective of this study to examine the effect body weight reduction on serum irisin level physical indicators obese Japanese patients without diabetes.The subjects were 22 (male/female, 5/17; age, 46.1±16.0 years; mass index [BMI], 36.9±5.0 kg/m2) who completed 6-month program at our clinic. included diet, exercise therapy cognitive behavioral therapy. Blood parameters, composition, tolerance, homeostasis model assessment...
Effects of ionizing radiation on the level genomic DNA methylation in liver, brain and spleen mouse as well two kinds cultured cells were examined by high-performance liquid chromatography. Ten Gy whole body X-radiation reduced 5-methyldeoxycytidine contents about 40% within 8 hours after irradiation liver. Similar effects observed at 4 or 7 X-ray irradiation. However, no such change was detected brain, cells. The data indicate that radiation-induced alteration is not ubiquitous among...
We measured and compared the levels of plasma soluble (s) P-selectin, sCD40L, platelet-derived microparticles (PDMP), monocyte-derived (MDMP), anti-oxidized LDL antibody, to obtain a better understanding their potential contribution vascular complications in acute coronary syndrome (ACS). The concentrations sP-selectin, PDMP, MDMP ACS patients were significantly higher than those normal controls with stable angina. When these markers differences concentration all high level antibody. Next,...
We investigated the mechanism of exercise-induced late cardioprotection against ischemia-reperfusion (I/R) injury. C57BL/6 mice received treadmill exercise (60 min/day) for 7 days at a work rate 60-70% maximal oxygen uptake. Exercise transiently increased oxidative stress and activated endothelial isoform nitric oxide synthase (eNOS) during expression inducible NOS (iNOS) in heart after exercise. The were subjected to regional ischemia by 30 min occlusion left coronary artery, followed 2 h...
Background It has recently been suggested that skeletal muscle an important role in insulin resistance obesity, addition to exercise tolerance and the fat index. The aim of this study was identify body composition factors contribute improvement female patients with obesity who reduce weight. Methods We studied 92 obese (age 40.9±10.4 years, mass index 33.2±4.6 kg/m2) reduced weight by â¥5% after intervention program including diet, therapy, cognitive behavioral therapy. Before...
Nanoscopic characterization of light-emitting materials is essential to realize nano-optical devices, which requires nanoscopic spatial resolution far beyond the diffraction limit light. Cathodoluminescence (CL) a powerful means achieve such by combining with electron microscopy. However, discrimination between coherent and incoherent CL emissions, when phosphor material combined resonator, not trivial. To solve this general problem in coupled emitter-resonator systems, we take advantage...
Abnormalities in fibrinolysis, endothelial function, and glucose lipid metabolism have been reported hypertension. This study was conducted to examine the interrelationships between fibrinolytic factors, metabolism, function The effects of administering an angiotensin converting enzyme inhibitor, benazepril, were also examined. Blood levels following substances measured patients with borderline mild hypertension (n=50, 51±19 years) age-matched controls (n=10): total cholesterol,...
Although stem cell transplantation (SCT) is being used for hematopoietic reconstitution following high-dose chemotherapy malignancy, it involves certain serious transplant-related complications such as graft-versus-host disease (GVHD). Angiopoietins play important roles in angiogenesis. However, the role of angiopoietins after SCT poorly understood. In this study, 52 patients underwent SCT; 26 received allogeneic SCT, while remaining autologous SCT. 48 patients, levels angiopoietins,...
The effects of treatment with pitavastatin on inflammatory and platelet activation markers adiponectin in 117 patients hyperlipidemia were investigated to determine whether may prevent the progression atherosclerotic changes hyperlipidemic patients. Adiponectin levels prior without diabetes lower than normolipidemic controls. Both total cholesterol low-density lipoprotein decreased significantly after administration. Additionally, or type 2 exhibited a significant increase 6 months...