- Cardiac Valve Diseases and Treatments
- Light effects on plants
- Cardiac Structural Anomalies and Repair
- Cardiac Imaging and Diagnostics
- Blood Pressure and Hypertension Studies
- Cardiac tumors and thrombi
- Neuroblastoma Research and Treatments
- Infective Endocarditis Diagnosis and Management
- Heart Rate Variability and Autonomic Control
- Aortic Disease and Treatment Approaches
- Greenhouse Technology and Climate Control
- Intestinal Malrotation and Obstruction Disorders
- Cardiovascular Function and Risk Factors
- Congenital Diaphragmatic Hernia Studies
- Cardiovascular Health and Disease Prevention
- Hormonal Regulation and Hypertension
- Pediatric Hepatobiliary Diseases and Treatments
- Congenital Heart Disease Studies
- Gallbladder and Bile Duct Disorders
- Aluminum Alloy Microstructure Properties
- Salivary Gland Disorders and Functions
- Urological Disorders and Treatments
- Microstructure and mechanical properties
- Coronary Artery Anomalies
- Pericarditis and Cardiac Tamponade
Educational Service District 123
2018-2025
Chiba University
2013-2024
Kawasaki Medical School
2021-2024
Kawasaki Hospital
2024
University of Tsukuba
1999-2022
Hiroshima City Asa Citizens Hospital
2017-2021
Kowa (Japan)
2010-2021
Tsukuba University of Technology
2021
Hiroshima Prefectural Hospital
2014-2016
City Hospital
1994-2015
Abstract Background Rikkunshito, a standardized J apanese herbal medicine, is thought to accelerate gastric emptying and relieve dyspepsia, although no large‐scale, randomized, placebo‐controlled trials of rikkunshito have been conducted. This study aimed determine the efficacy safety for treating functional dyspepsia ( FD ). Methods patients received 2.5 g or placebo three times day 8 weeks in this multicenter, placebo‐controlled, parallel‐group trial. The primary end point was proportion...
We studied the effects of varying light quality on flowering, photosynthetic rate and fruit yield everbearing strawberry plants (
This study aimed to analyze the effects of photosynthetic photon flux density (PPFD) on fruit biomass radiation-use efficiency (FBRUE) dwarf tomato cultivar ‘Micro-Tom’ and determine suitable PPFD for enhancing FBRUE under LED light at reproductive growth stage. We performed four treatments white light: 200, 300, 500, 700 μmol m −2 s −1 . The results demonstrated that a higher led fresh dry weights plants lowered specific leaf areas. (RUE) were highest 300 decreased by 37.7% because RUE 25%...
Coronary blood flow occurs mainly during the diastolic phase of each cardiac cycle and is dependent on driving pressure, especially in left anterior descending coronary artery (LAD). We hypothesized that calculation ratio pressure a stenotic LAD to its normal value, namely FFR (d-FFR), might provide precise insight into mechanism for assessment functional severity stenosis. compared d-FFR with FFR, reserve (CFR), exercise myocardial thallium scintigraphy an lesion intermediate severity.The...
Dwarf tomatoes are advantageous when cultivated in a plant factory with artificial light because they can grow well small volume. However, few studies have been reported on cultivation controlled environment for improving productivity. We performed two experiments to investigate the effects of photosynthetic photon flux density (PPFD; 300, 500, and 700 μmol m-2 s-1) white quality (white, R3B1 (red:blue = 3:1), R9B1) PPFD 300 s-1 growth radiation-use efficiency (RUE) dwarf tomato cultivar...
Retinoic acid-inducible gene-I (RIG-I) is a putative RNA helicase involved in immune reactions against viruses and various inflammatory autoimmune diseases. The purpose of the present study was to investigate role RIG-I glomerular diseases.We treated human mesangial cells culture with polyinosinic-polycytidylic acid (poly IC), which an authentic double-stranded RNA, analysed expression RIG-I, CC chemokine ligand 5 (CCL5) interferon (IFN)-β by western blotting, reverse...
Abstract Mutations of Fas (lpr) or ligand (gld) cause a limited lupus-like syndrome in B6 mice by interfering with the deletion autoreactive B and/or T cells. A more generalized lupus reminiscent that MRL can be induced nonautoimmune strains pristane, which causes nonspecific inflammatory response peritoneal cavity. We hypothesized that, as mice, lpr and gld mutations might accelerate pristane-treated mice. Pristane-treated developed anti-nRNP/Sm, Su, ribosomal P Abs, but little anti-ssDNA...
Abnormalities in fibrinolysis, endothelial function, and glucose lipid metabolism have been reported hypertension. This study was conducted to examine the interrelationships between fibrinolytic factors, metabolism, function The effects of administering an angiotensin converting enzyme inhibitor, benazepril, were also examined. Blood levels following substances measured patients with borderline mild hypertension (n=50, 51±19 years) age-matched controls (n=10): total cholesterol,...
Conventional and enhanced computed tomographic (CT) examinations were performed in 103 patients with myocardial infarction for evaluation of the diagnostic usefulness CT. After intravenous bolus injection contrast material, an initial filling defect late enhancement infarcted myocardium appeared on cardiac CT images. These two findings direct evidence infarction; former was found mostly patient recent infarctions, latter recognized both those "remote" infarctions. Wall thinning at site by...
Abstract Congenital diaphragmatic hernia (CDH) is a birth defect of the diaphragm in which abdominal organs herniate through into thoracic cavity. The main pathophysiology respiratory distress and persistent pulmonary hypertension because hypoplasia caused by compression elevated organs. Recent progress prenatal diagnosis postnatal care has led to an increase survival rate patients with CDH. However, some survivors experience mid‐ long‐term disabilities complications requiring treatment...
Abstract Objective This study examined the interactions between exogenous and endogenous factors shaping phenotype of lupus in autoimmune (NZB × NZW)F 1 mice exposed to pristane, a model environmental trigger. Methods Frequencies various autoantibodies untreated NZB/NZW were determined by means (immunoprecipitation, enzyme‐linked immunosorbent assay [ELISA], Crithidia luciliae kinetoplast staining). Pristane or saline was administered intraperitoneally 9–12‐week‐old mice, followed serial...
To evaluate the affinity of clarithromycin (6-O-methylerythromycin A) for lung tissue, in-vivo and in-vitro uptake [14C]clarithromycin [14C]erythromycin by rat cells was compared, characteristics mechanism were investigated. After administration into external jugular vein rats, found in much higher concentrations tissue than erythromycin. In isolated cells, also greater The amount ten times that erythromycin after 5 min incubation. This profile quite different from observed liver cells....