A5083849961- Bacterial biofilms and quorum sensing
- Gut microbiota and health
- Antibiotic Resistance in Bacteria
- Clostridium difficile and Clostridium perfringens research
- Gastrointestinal motility and disorders
- Diet and metabolism studies
- Biosensors and Analytical Detection
- Microbial Metabolism and Applications
- Vibrio bacteria research studies
- Force Microscopy Techniques and Applications
- Infections and bacterial resistance
- Bacterial Identification and Susceptibility Testing
- Escherichia coli research studies
- Oral microbiology and periodontitis research
- Pharmaceutical and Antibiotic Environmental Impacts
- Viral gastroenteritis research and epidemiology
- Vector-Borne Animal Diseases
- Listeria monocytogenes in Food Safety
- Antimicrobial Resistance in Staphylococcus
- Probiotics and Fermented Foods
- Vector-borne infectious diseases
- Cystic Fibrosis Research Advances
- Wastewater Treatment and Reuse
- Biochemical and Structural Characterization
- Viral Infections and Vectors
Sapienza University of Rome
2013-2024
Italian Institute of Technology
2015
Istituto Superiore di Sanità
2015
Microbiology Society
2011
University of Rome Tor Vergata
1999
Czech Academy of Sciences, Institute of Microbiology
1999
Aims: To analyse the environmental stimuli modulating violacein and biofilm production in Janthinobacterium lividum. Methods Results: Violacein by J. lividum DSM1522T was assayed different growth conditions. Our data suggest that is controlled carbon source, being inhibited glucose enhanced glycerol. produced also presence of sub‐inhibitory concentrations ampicillin. As opposite, N‐acylhomoserine lactone(s), quorum sensing regulators shown to be positively regulated glucose. Moreover,...
Bdellovibrio bacteriovorus is a predator bacterial species found in the environment and within human gut, able to attack Gram-negative prey. Cystic fibrosis (CF) genetic disease which usually presents lung colonization by Pseudomonas aeruginosa or Staphylococcus aureus biofilms. Here, we investigated predatory behaviour of B. against these two pathogenic with: i) broth culture; ii) 'static' biofilms; iii) field emission scanning electron microscope (FESEM); iv) 'flow' v) zymographic...
Literature data provide little information about protozoa infections and gut microbiota compositional shifts in humans. This preliminary study aimed to describe the fecal bacterial community composition of people from Côte d'Ivoire harboring Giardia duodenalis, Entamoeba spp., Blastocystis hominis, trying discover possible alterations their structure related presence such parasites.Twenty samples were collected inhabiting three different localities for copromicroscopic analysis molecular...
Violacein (VIO; 3-[1,2-dihydro-5-(5-hydroxy-1H-indol-3-yl)-2-oxo-3H-pyrrol-3-ylidene]-1,3-dihydro-2H-indol-2-one), an indole-derived purple-colored pigment, produced by a limited number of Gram-negative bacteria species, including Chromobacterium violaceum and Janthinobacterium lividum, has been demonstrated to have anti-cancer activity, as it interferes with survival transduction signaling pathways in different cancer models. Head neck carcinoma (HNC) represents the sixth most common one...
Antibiotic resistant bacteria (ARB) have been found on fresh fruit and vegetables globally. These types of ARB infections are spreading rapidly a major human health threat. A quantitative exposure assessment model was created using scenario analysis to investigate the potential antibiotic Escherichia coli (AR-E. coli) through consumption lettuce irrigated with surface water. Scientific literature site specific data were collected each process from farm fork calculate concentration AR-E. at...
Background: Prevention of foodborne diseases is a fundamental goal for public health and industries engaged in food preparation distribution. The correct procedure to ensure an effective prevention consists essentially microbiological monitoring enumeration indicator microorganisms faecal contamination at critical control points along the producing procedures. Here, we propose new biosensor, called FoodBioTimerAssay (FBTA), rapid reliable detection Escherichia coli as surface samples....
Eleven environmental samples from different sources were screened for the presence of metallo-beta-lactamase-producing bacteria by using a selective enrichment medium containing carbapenem antibiotic and subsequently testing each isolate production EDTA-inhibitable carbapenemase activity. A total 15 isolates, including 10 Stenotrophomonas maltophilia 3 Chryseobacterium spp., one Aeromonas hydrophila isolate, Janthinobacterium lividum (a species in which metallo-beta-lactamase activity was...
Rheumatoid Arthritis (RA) is a chronic systemic autoimmune disease. Modifications of gut microbiota seem to be associated with the disease, but impact on therapies' outcome remains unclear. A role T cells in RA pathogenesis has been addressed, particularly Th17/Treg balance. Our study aimed evaluate early (ERA) patients compared control group, fecal composition, short-chain fatty acids concentrations, and levels circulating their own cytokines, before after 3 months standard treatment...
ABSTRACT The sequenced chromosome of Caulobacter crescentus CB15 encodes a hypothetical protein that exhibits significant similarity (30 to 35% identical residues) metallo-β-lactamases subclass B3. An allelic variant this gene (divergent by 3% its nucleotides) was cloned in Escherichia coli from C. type strain DSM4727. Expression studies confirmed the metallo-β-lactamase activity product, CAU-1. enzyme produced E. purified two ion-exchange chromatography steps. CAU-1 contains 29-kDa...
In cystic fibrosis (CF) high iron concentration in airway secretion plays a pivotal role bacterial multiplication and biofilm formation as well inflammatory response. Burkholderia cenocepacia, an opportunistic facultative pathogen responsible for chronic lung infections cepacia syndrome, recurrently infects CF patients. Lactoferrin (Lf), binding multifunctional glycoprotein synthesized by exocrine glands neutrophils, has been found at higher the secretions of infected patients than healthy...
Background: Wastewater treatment plants (WWTPs) are microbial factories aimed to reduce the amount of nutrients and pathogenic microorganisms in treated wastewater before its discharge into environment. We studied impact urban WWTP effluents on abundance antibiotic resistance genes (ARGs) antibiotic-resistant Escherichia coli (AR-E. coli) last stretch two rivers (Arrone Tiber) Central Italy that differ size flow volume. Methods: Water samples were collected three seasons upstream downstream...
Several studies have shown fluctuations in the maternal microbiota at various body sites (gut, oral cavity, and vagina). The skin plays an important role our health, but on changes during pregnancy are limited. Quantitative qualitative variations pregnant woman could indeed play roles modifying immune inflammatory responses of host. These alterations induce disorders affecting individual's dermal properties, potentially predict infant disorder unborn. present study aimed to characterize...
Lyme borreliosis is a disease caused by spirochaetes belonging to the genospecies complex Borrelia burgdorferi sensu lato (s.l.) transmitted Ixodes ticks. At present, serology remains main diagnostic tool for laboratory diagnosis of borreliosis. Recently, PCR technique has been applied B. s.l., but, until now, reliable, easy-to-perform and sensitive method not described. Here we present new PCR-based detection both s.l. DNAs in serum samples collected from patients showing symptoms. Of 265...
The pathogenesis of salivary calculi is not yet clear; however, 2 theories have been formulated: (1) "the classic theory," based on calcium microdeposits in serous and ductal acinous cells, successively discharged into the ducts; (2) retrograde a migration food, bacteria, so from oral cavity to duct. aim present study highlight role bacteria biofilm stone formation.Case series without comparison.Laboratory Department Anatomical Pathology.Traditional optic microscopy scanning electron were...