A5014918016- Advanced Fluorescence Microscopy Techniques
- Circular RNAs in diseases
- Cancer-related molecular mechanisms research
- Photoacoustic and Ultrasonic Imaging
- MicroRNA in disease regulation
- RNA modifications and cancer
- Cancer-related gene regulation
- Advanced Electron Microscopy Techniques and Applications
- Optical Coherence Tomography Applications
- Fault Detection and Control Systems
- RNA Research and Splicing
- Hydraulic Fracturing and Reservoir Analysis
- Rice Cultivation and Yield Improvement
- Hydrocarbon exploration and reservoir analysis
- Cell Image Analysis Techniques
- Breast Cancer Treatment Studies
- Cancer Cells and Metastasis
- Esophageal Cancer Research and Treatment
- Genetic Mapping and Diversity in Plants and Animals
- RNA regulation and disease
- EEG and Brain-Computer Interfaces
- Immune Cell Function and Interaction
- Blind Source Separation Techniques
- Natural Products and Biological Research
- Embedded Systems and FPGA Applications
Fujian Medical University
2019-2025
Hubei University of Technology
2011-2025
Jiangsu University
2016-2024
Henan University
2024
Affiliated Hospital of Jiangsu University
2013-2024
Henan University Huaihe Hospital and Huaihe Clinical Institute
2024
Civil Aviation Flight University of China
2023
China University of Petroleum, East China
2022
Xijing Hospital
2022
Air Force Medical University
2022
Grain size is one of key agronomic traits that determine grain yield in rice. Several regulators have been identified rice, but the mechanisms and remain largely unknown.Here we characterize a small (smg11) mutant which exhibits grains, dense panicles increased number grains per panicle. Cloning sequence analyses SMG11 gene reveal smg11 new allele DWARF2 (D2), encodes cytochrome P450 (CYP90D2) involved brassinosteroid biosynthetic pathway. Overexpression D2/SMG11 increases weight wild-type...
Abstract In this study, we explored expression and functions of circular RNA LPAR3 (circLPAR3) in esophageal squamous cell carcinoma (ESCC). The differential RNAs (circRNAs) 10 ESCC corresponding paracarcinoma tissues was analyzed through circRNA microarray, then the candidate circRNAs were detected verified quantitative RT‐PCR, a novel screened, which circLPAR3. Circular showed apparently high cells, closely correlated with clinical stage lymph node metastasis patients. mainly located...
The notion of personalized medicine demands proper prognostic biomarkers to guide the optimal therapy for an invasive breast cancer patient. However, various risk prediction models based on conventional clinicopathological factors and emergent molecular assays have been frequently limited by either a low strength prognosis or restricted applicability specific types patients. Therefore, there is critical need develop strong general prognosticator.
Panicle size and grain number are important agronomic traits influence yield in rice (Oryza sativa), but the molecular genetic mechanisms underlying panicle control remain largely unknown crops. Here we report that LARGE2 encodes a HECT-domain E3 ubiquitin ligase OsUPL2 regulates rice. The loss of function large2 mutants produce large panicles with increased number, wide grains leaves, thick culms. by repressing meristematic activity. is highly expressed young grains. Biochemical analyses...
Abstract RNA-binding proteins (RBPs) modulate the expression level of several target RNAs (such as mRNAs) post-transcriptionally through interactions with unique binding sites in 3′-untranslated region. There is mounting information that suggests RBP dysregulation plays a significant role carcinogenesis. However, function FMR1 autosomal homolog 1(FXR1) malignancies just beginning to be unveiled. Due diversity their domains and functional adaptability, FXR1 can regulate diverse transcript...
High penetration of wind power in the modern system renders traditional automatic generation control (AGC) methods more challenging, due to uncertainty external environment, less reserve power, and small inertia constant system. An improved AGC method named predictive optimal 2-degree-of-freedom proportion integral differential (PO-2-DOF-PID) is proposed this paper, which farm will participate load frequency process. Firstly, mathematical model multi-area grid with built. Then, PID...
Circle RNAs (circRNAs) are the novel noncoding with covalent closed-loop structure, which play a crucial role in variety of pathological processes, including cancer. Nevertheless, expression profiles and functions circRNAs esophageal squamous cell cancer (ESCC) remain largely unknown. In this paper, 10 pairs ESCC tissues were utilized to screen circRNA by means microarray assay; further, circular RNA named hsa_circ_0006168 was investigated. Meanwhile, measured 52 lines. Our results suggested...
Abstract The positive results of the apatinib phase III trial have cast new light on treatment for patients with advanced gastric cancer (GC). However, in terms safety, toxicities may lead to a dose modification or interruption. Therefore, proper intervention is urgently needed help benefit from treatment. In this study, we found that promoted autophagy activation via upregulation ATG7 expression and inhibition enhanced apatinib-induced apoptosis. With microRNA circular RNA-sequencing...
Nonsmall cell lung cancer (NSCLC) is the major cause of death worldwide. Increasing evidence shows that noncoding RNAs (ncRNAs) are widely involved in development and progression NSCLC. ncRNA small nucleolar RNA host gene 1 (SNHG1) has not been studied cancer, especially its role remains unknown. Our studies were designed to investigate expression biological significance SNHG1 cancer. may be a novel early diagnosis cancer.Noncoding 7 lines was measured by quantitative real-time polymerase...
Recent evidence indicates that long noncoding RNAs (lncRNAs) play pivotal roles in the regulation of cellular processes and are found to be dysregulated a variety cancers. LINC00261 is an lncRNA aberrantly expressed gastric cancer (GC). The clinical role GC molecular mechanisms remains found. Real-time polymerase chain reaction (PCR) was used examine expression cell lines/tissues compared with normal epithelial cells/adjacent non-tumorous tissues. Gain loss function approaches were...
Various new technologies for conversion between different forms of energy promote the appearance hybrid multi-carrier system. For purpose optimized dispatch and security requirement system, reliability this kind system needs to be discussed. This article proposes a method based on entropy-based Markov model analyze First, obtain individual carrier is Second, characteristic analyzed. The shown an effective technique whole depending carrier. Then, fusion process described. result indicates...
The growing body of evidence suggests that RNA-binding proteins (RBPs) have an important function in cancer biology. This research characterizes the expression status fragile X-related protein 1 (FXR1) esophageal (ESCA) cell lines and understands its mechanistic importance ESCA tumor
The biological behavior of tumor cells is closely related to invasion, but the relationship between spatial distribution at invasion boundary and prognosis still unknown. In this study, we based Multiphoton Microscopy (MPM) image Tumor-Associated Collagen Signatures (TACS), a biomarker known be associated with Breast Cancer (BC) captured 180μm × regions interest (ROI) on its colocalization hematoxylin eosin (H&E) images. deep neural network was used extract 51 microscopic features from H&E...
Circular RNA (circRNA) is an endogenous noncoding RNA. Accumulative investigations have confirmed that circRNAs play a vital role in carcinogenesis and tumor progression. Herein, we examined the expression mechanism of circ_0072088 esophageal squamous cell carcinoma (ESCC). As result, was significantly overexpressed ESCC tissues cells, which closely associated with size, invasion depth, clinical stage, lymph node metastasis cancer. Nuclear cytoplasmic separation as well FISH assays showed...
In order to improve wind power prediction accuracy and increase the utilization of power, this study proposes a novel complete ensemble empirical mode decomposition with adaptive noise (CEEMDAN)–variational modal (VMD)–gated recurrent unit (GRU) model. With goal extracting feature information that existed in temporal series data, CEEMDAN VMD are used divide raw data into several intrinsic function components. Furthermore, reduce computational burden enhance convergence speed, these (IMF)...
With the increased uses of targeted therapeutics, diagnostic detection target mutations becomes essential for effective clinical applications therapeutics. Currently, there are two types methods detecting in clinics: one is based on DNA sequence and other newly developed mutation-specific antibodies recognizing mutated proteins. Each method has its own advantages disadvantages. Here, we explored sensitivity specificity a new commercially available BRAF(V600E) mouse monoclonal antibody. Using...