Maria Rendina
- Liver Disease Diagnosis and Treatment
- Hepatitis C virus research
- Liver Disease and Transplantation
- Hepatitis B Virus Studies
- Organ Transplantation Techniques and Outcomes
- Liver Diseases and Immunity
- Renal Transplantation Outcomes and Treatments
- Drug-Induced Hepatotoxicity and Protection
- Helicobacter pylori-related gastroenterology studies
- Systemic Lupus Erythematosus Research
- Hepatocellular Carcinoma Treatment and Prognosis
- Polyomavirus and related diseases
- Diabetes and associated disorders
- Viral-associated cancers and disorders
- SARS-CoV-2 and COVID-19 Research
- Cytomegalovirus and herpesvirus research
- Gastrointestinal disorders and treatments
- Inflammatory Bowel Disease
- Transplantation: Methods and Outcomes
- Gastric Cancer Management and Outcomes
- Alcohol Consumption and Health Effects
- Microscopic Colitis
- Silymarin and Mushroom Poisoning
- COVID-19 Clinical Research Studies
- Nutrition and Health in Aging
Azienda Universitaria Ospedaliera Consorziale - Policlinico Bari
2003-2025
University of Bari Aldo Moro
2014-2024
Istituto Superiore di Sanità
2021
Italian Medicines Agency
2018
University of Naples Federico II
2018
University of Pittsburgh
2016
Hospital Universitario Reina Sofía
2013
Italian Association for Cancer Research
2013
The Royal Free Hospital
2013
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2013
Three–hundred and twenty–four patients were enrolled in an open–label, multicenter, international study which pre– post–liver transplantation (LT) with recurrent chronic hepatitis B (CHB) evidence of lamivudine–resistant HBV treated adefovir dipivoxil 10 mg once daily. In the post–LT cohorts, 128 196 for a median duration 18.7 56.1 weeks, respectively. who received 48 weeks treatment, 81% pre–LT 34% cohort achieved undetectable serum virus (HBV) DNA (Roche Amplicor Monitor TM polymerase...
Sarcopenia and myosteatosis are common in patients with cirrhosis. This study aimed to determine the prevalence of these muscle changes, their interrelations prognostic impact over a 12-month period.
Patients with hepatocellular carcinoma should be managed a multidisciplinary approach framed in network where all the diagnostic techniques and therapeutic resources are available order to provide optimal level of care. Given this assumption, Coordinating Committee Italian Association for Study Liver nominated panel experts elaborate practical recommendations management aiming provide: (1) homogeneous efficacious staging work-up, (2) best treatment choice tailored patient status tumour stage...
Chronic hepatitis C is the main cause of death in patients with end-stage liver disease. Prognosis depends on increase fibrosis, whose progression twice as rapid men women. Aim study was to evaluate effects reproductive stage fibrosis severity women and compare these findings age-matched men.A retrospective 710 consecutive biopsy-proven chronic conducted, using data from a clinical database two tertiary Italian care centers. Four groups served controls. Data about demographics, biochemistry,...
Liver stiffness measurement (LSM) by Fibroscan is the most used non-invasive method to assess liver fibrosis. Recently, point-shear wave elastography (pSWE) has been introduced as a simple alternative test. Therefore, we aimed compare results of these two techniques. One hundred and eighty-four consecutive patients attending our outpatient ultrasound clinic were recruited. LSM was performed both pSWE. Statistical analysis conducted Spearman’s test for correlation linear regression....
Abstract Natural resistance-associated substitutions (RASs) are reported with highly variable prevalence across different HCV genotypes (GTs). Frequency of natural RASs in a large Italian real-life cohort patients infected the 4 main HCV-GTs was investigated. NS3, NS5A and NS5B sequences were analysed 1445 HCV-infected DAA-naïve patients. Sanger-sequencing performed by home-made protocols on 464 GT1a, 585 GT1b, 92 GT2c, 199 GT3a, 16 GT4a 99 GT4d samples. Overall, 20.7% (301/1455) showed...
BackgroundInternational consensus has recently introduced a new definition of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD). We sought to analyse epidemiological trends, prognostic features, and transplant survival benefits MASLD non-MASLD patients waiting for liver transplantation (LT) in Italy.Materials methodsUtilising the Italian Transplant Registry database, we analysed data from adult listed primary LT due end-stage chronic disease between January 2012 December 2022....
Aim: To report the results of a prospective, open‐label, uncontrolled study in 13 patients affected by Crohn’s disease with resistance to steroids. Methods: The were treated long‐term oral tacrolimus, aiming both resolve acute attacks and maintain remission. Tacrolimus was administered at dose 0.1–0.2 mg.day/kg adjusted order achieve levels 5–10 ng/mL; only mesalazine continued concomitantly. Steroids total parenteral nutrition tapered when appropriate. Results: Median treatment 27.3 months....
In the setting of liver transplant (LT), survival after diagnosis de novo malignancies (DNMs) has been poorly investigated. this study, we assessed impact DNMs on LT recipients as compared to corresponding without DNM. A nested case-control study was conducted in a cohort 2,818 enrolled nine Italian centres between 1985 and 2014. Cases were 244 who developed LT. For each case, two controls matched for gender, age, year at selected by incidence density sampling among members The probabilities...
Hepatitis B virus (HBV) infection is a major global health concern, with liver transplantation (LT) serving as critical treatment for end-stage disease caused by HBV. However, the risk of HBV reinfection after LT remains significant, necessitating effective prophylaxis. Today, combination hepatitis immune globulin (HBIG) and high-barrier nucleos(t)ide analogues (NUCs) standard care preventing recurrence post-LT but concerns about cost HBIG access to NUCs have led reduction in use, dose,...
Patients with HDV/HBV-related end-stage liver disease candidates for transplantation(LT) have traditionally been regarded as a special population, although their outcomes are controversial. A intention-to-treat(ITT) analysis of long-term HDV/HBV-coinfected patients waitlisted LT in Italy, between 2011-2020, was performed and compared to HBV-monoinfected candidates. Out 1,731 HBV-infected candidates, 1,237(71.5%) had HBV-monoinfection 494(28.5%) HDV/HBV-coinfection. At listing, were...