Gloria Taliani
A5059586370- Hepatitis C virus research
- Liver Disease Diagnosis and Treatment
- Hepatitis B Virus Studies
- Liver Disease and Transplantation
- Systemic Lupus Erythematosus Research
- Hepatitis Viruses Studies and Epidemiology
- HIV/AIDS drug development and treatment
- Pneumonia and Respiratory Infections
- Liver Diseases and Immunity
- COVID-19 Clinical Research Studies
- HIV Research and Treatment
- Heart Failure Treatment and Management
- Polyomavirus and related diseases
- Chronic Lymphocytic Leukemia Research
- Drug-Induced Hepatotoxicity and Protection
- Long-Term Effects of COVID-19
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Amoebic Infections and Treatments
- Parvovirus B19 Infection Studies
- Parasitic Infections and Diagnostics
- Viral gastroenteritis research and epidemiology
- Cytomegalovirus and herpesvirus research
- Diabetes and associated disorders
- Venous Thromboembolism Diagnosis and Management
Sapienza University of Rome
2016-2025
Policlinico Umberto I
2015-2024
Dipartimento della Protezione Civile
2021
Azienda Ospedaliera S.Giuseppe Moscati
2021
Guglielmo da Saliceto Hospital
2021
Ospedaliera di Piacenza
2020
University of Bologna
2020
Weatherford College
2019
Azienda Ospedaliera Universitaria Università degli Studi della Campania Luigi Vanvitelli
2019
Italian Medicines Agency
2018
Previous reports suggest that community-acquired pneumonia (CAP) is associated with an enhanced risk of cardiovascular complications. However, a contemporary and comprehensive characterization this association lacking. In multicenter study, 1182 patients hospitalized for CAP were prospectively followed up to 30 days after their hospitalization infection. Study endpoints included myocardial infarction, new or worsening heart failure, atrial fibrillation, stroke, deep venous thrombosis, death,...
Recent reports suggested that direct acting antivirals (DAAs) might favor hepatocellular carcinoma (HCC). In study 1, we studied the proangiogenic liver microenvironment in 242 DAA-treated chronic hepatitis C patients with advanced fibrosis. Angiopoietin-2 (ANGPT2) expression was tissue (cirrhotic and/or neoplastic) from recurrent, de novo, nonrecurrent HCC, or never developing HCC. Circulating ANGPT2,vascular endothelial growth factor (VEGF), and C-reactive protein (CRP) were also measured....
Few data are available on the virological and clinical outcomes of advanced liver disease patients retreated after first-line DAA failure.
Abstract Objective The aim of this study was to identify the main CT features that may help in distinguishing a progression interstitial lung disease (ILD) secondary SSc from COVID-19 pneumonia. Methods This multicentric included 22 international readers grouped into radiologist group (RADs) and non-radiologist (nRADs). A total 99 patients, 52 with 47 SSc-ILD, were study. Results Fibrosis inside focal ground-glass opacities (GGOs) upper lobes; fibrosis lower lobe GGOs; reticulations lobes...
Pneumonia is complicated by high rate of mortality and cardiovascular events (CVEs). The potential benefit aspirin, which lowers platelet aggregation inhibition thromboxane A2 production, still unclear. aim the study was to assess impact aspirin on in patients with pneumonia.Consecutive admitted University-Hospital Policlinico Umberto I (Rome, Italy) community-onset pneumonia were recruited prospectively followed up until discharge or death. primary end point occurrence death 30 days after...
Abstract Background & Aims Despite the excellent efficacy of direct‐acting antivirals ( DAA ) reported in clinical trials, virological failures can occur, often associated with development resistance‐associated substitutions RAS s). This study aimed to characterize presence clinically relevant s all classes real‐life failures. Methods Of 200 that were analyzed 197 ‐treated patients, 89 pegylated‐interferon+ribavirin (Peg IFN + RBV and 111 without HCV ‐1a/1b/1g/2/3/4=58/83/1/6/24/25;...
Introduction The diffusion of multidrug-resistant (MDR) bacteria has created the need to identify risk factors for acquiring resistant pathogens in patients living community. Objective To analyze clinical features with community-onset pneumonia due MDR pathogens, evaluate performance existing scoring tools and develop a bedside score an early identification these Emergency Department. Patients Methods This was open, observational, prospective study consecutive pneumonia, coming from...
Prevalence of anti-hepatitis E virus (HEV) antibodies is highly variable in developed countries, which seems partly due to differences assay sensitivity. Using validated sensitive assays, we tested 313 blood donors attending a hospital transfusion unit central Italy January and February 2014 for anti-HEV IgG IgM HEV RNA. Data on exposure were collected from all donors. Overall prevalence was 49% (153/313). Eating raw dried pig-liver sausage the only independent predictor infection (adjusted...
Due to the frequent presence of interstitial lung disease and widespread use immunosuppressive treatment, systemic sclerosis (SSc) patients may be considered at risk for a more severe course higher mortality when they develop Severe Acute Respiratory Syndrome - Coronavirus 2 (SARS-CoV-2) virus infection. Therefore, with World Scleroderma Foundation endorsement, experts from different specialties including rheumatology, virology clinical immunology gathered virtually answer main practical...
We designed a multicenter cross-sectional study to evaluate the role of alcohol abuse, hepatitis viruses and other pathogenic factors in cirrhosis hepatocellular carcinoma. A total 1,829 consecutive patients, with or without HCC, was enrolled over 6 mo 21 centers throughout Italy. The etiological categories diagnostic criteria were preestablished. median age patients 59 yr (range, 13 85 yr); 63.6% graded as Child class A, 23.4% B 13% C. Hepatitis C virus antibodies found 72.1% cases (47.7%...
This study examined 522 children born to hepatitis B surface antigen (HBsAg)-positive mothers from 1985 through 1994 and evaluated the protection provided by anti-hepatitis virus (HBV) immunization at birth. Babies were given immunoglobulin vaccine At 5-14 years after immunization, 17 (3.3%) anti-HB core positive, 3 also HBsAg positive. One carrier child had a double mutation, with substitution of proline-->serine codons 120 (P120S) 127 (P127S) within determinant HBsAg. Of children, 400...