A5002784509- Liver Disease Diagnosis and Treatment
- Diet, Metabolism, and Disease
- Liver Disease and Transplantation
- Lipid metabolism and disorders
- Hepatitis C virus research
- Hepatitis B Virus Studies
- Electrospun Nanofibers in Biomedical Applications
- Tissue Engineering and Regenerative Medicine
- Alcohol Consumption and Health Effects
- Endoplasmic Reticulum Stress and Disease
- Pancreatitis Pathology and Treatment
- Diet and metabolism studies
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Hepatocellular Carcinoma Treatment and Prognosis
- Diabetes and associated disorders
- Diabetic Foot Ulcer Assessment and Management
- Microstructure and Mechanical Properties of Steels
- Metallurgy and Material Forming
- Liver Diseases and Immunity
- Cardiovascular Disease and Adiposity
- Sepsis Diagnosis and Treatment
- Fibroblast Growth Factor Research
- Kruppel-like factors research
- Cardiovascular Function and Risk Factors
- Cancer, Lipids, and Metabolism
Wenzhou Medical University
2016-2025
First Affiliated Hospital of Wenzhou Medical University
2016-2025
Shanghai Ocean University
2022
Shanghai Harbour Engineering Design & Research Institute
2022
Peking Union Medical College Hospital
2019
Chinese Academy of Medical Sciences & Peking Union Medical College
2019
Nanjing University of Posts and Telecommunications
2018
Endocrinology Research Center
2017
State Key Laboratory of Natural Medicine
2016
X-Fab (Germany)
2016
Metabolic dysfunction-associated steatotic liver disease (MASLD) is currently the most common chronic worldwide. It important to develop noninvasive tests assess severity and prognosis.
Current guidelines recommend a 2-step approach for risk stratification in patients with metabolic dysfunction-associated steatotic liver disease (MASLD) Fibrosis-4 index (FIB-4) followed by stiffness measurement (LSM) vibration-controlled transient elastography (VCTE) or similar second-line tests. This study aimed to examine prognostic performance of this approach. The VCTE-Prognosis Study was longitudinal MASLD who had undergone VCTE examinations at 16 centres from the US, Europe and Asia...
A skeletal muscle strength (SMS) decline is associated with metabolic diseases, but whether SMS also declines chronic kidney disease (CKD) in individuals dysfunction-associated steatotic liver (MASLD) uncertain. This study examined the associations between and risk of CKD MASLD population. We performed a large-scale four cohorts: PERSONS NHANES 2011-2014 cohorts for cross-sectional investigation, TCLSIH UK Biobank longitudinal investigation. handgrip dynamometer measured as proxy overall...
// Jie You 1, 2, * , Gui-Qi Zhu 3, 4, Linka Xie 5, Wen-Yue Liu 6 Liang Shi 7 Ou-Chen Wang 1 Zong-Hai Huang 2 Martin Braddock 8 Gui-Long Guo Ming-Hua Zheng 9 Department of Oncological Surgery, The First Affiliated Hospital Wenzhou Medical University, 325000, China General Zhujiang Hospital, Southern Guangzhou 510282, 3 Infection and Liver Diseases, Research Center, 4 School Clinical Sciences, 5 Cancer Center Union Tongji College, Huazhong University Science Technology, Wuhan 430022,...
Objectives The relationship between normal low-density lipoprotein cholesterol (LDL-c) levels and non-alcoholic fatty liver disease (NAFLD) in non-obese individuals remains unclear. We aimed to investigate the precise prevalence incidence of NAFLD within LDL-c range individuals. Design Cross-sectional longitudinal study. Setting Wenzhou Medical Center People's Hospital from 2010 2014. Participants 183 903 were enrolled a cross-sectional population, total 16 173 initially NAFLD-free included...
Women younger than 40 years may face early menopause because of premature ovarian failure (POF). The cause POF can be idiopathic or iatrogenic, especially the cancer-induced oophorectomy and chemo- radiation therapy. current treatments, including hormone replacement therapy (HRT) cryopreservation techniques, have increased risk cancer reintroduce malignant cells after autografting. Decellularization technique has been regarded as a novel regenerative medicine strategy for organ replacement,...
// Dan-Qin Sun 1 * , Wen-Yue Liu 2 Sheng-Jie Wu 3 Gui-Qi Zhu 4, 5 Martin Braddock 6 Dong-Chu Zhang 7 Ke-Qing Shi 8 Dan Song Ming-Hua Zheng Department of Nephrology, Affiliated Wuxi Second Hospital, Nanjing Medical University, 214002, China Endocrinology, the First Hospital Wenzhou 325000, Cardiovascular Medicine, Heart Center, 4 Infection and Liver Diseases, Research School Clinical Sciences, Global Medicines Development, AstraZeneca R&D, Alderley Park, United Kingdom People's Institute...
Model for end-stage liver disease (MELD) scoring was initiated using traditional statistical technique by assuming a linear relationship between clinical features, but most phenomena in situation are not linearly related. The aim of this study to predict 3-month mortality risk acute-on-chronic hepatitis B failure (ACHBLF) on an individual patient level artificial neural network (ANN) system. ANN model built data from 402 consecutive patients with ACHBLF. It trained the 280 and validated...
Epidemiological data suggests a close link between metabolic syndrome (MetS) and non-metastatic colorectal cancer (NMCRC). However, the relationship MetS outcome of NMCRC is less well understood. We aim to evaluate impact on prognosis in patients.We performed large cohort study 1069 patients. The Kaplan-Meier method was used calculate cumulative survival rate. Cox proportional hazard regression models were analyze associated with adjusting for clinicopathologic variables.MetS identified...
Abstract Backgrounds There is a discrepancy between west and east on the relationship non-alcoholic fatty liver disease (NAFLD) chronic kidney (CKD). This study aimed to find out possible reason for this clarify association NAFLD CKD by analyzing two population-based datasets from US China. Methods Two health examination China were used. was defined as an estimated glomerular filtration rate (eGFR) < 60 ml/min/1.73m 2 or and/or abnormal albuminuria overt proteinuria. Binary logistic...
Background and Objectives Serum alanine aminotransferase (ALT) activity is the most common tool for assessment of liver diseases. However, it not clear whether current normal ALT range really discriminate patients with or without The present study was to establish a new examine its ability identify hepatitis B nonalcoholic fatty disease (NAFLD) in Chinese Han population. Methods 53037 adults were included this from January 1st 2008 August 31st 2010. 95th percentile population relative low...
Diabetic ketoacidosis (DKA) is a life-threatening acute complication of diabetes mellitus and the novel systemic inflammation marker platelet-to-lymphocyte ratio (PLR) may be associated with clinical outcome in patients DKA. This study aimed to investigate utility PLR predicting 90-day outcomes Patient data exacted from Multiparameter Intelligent Monitoring Intensive Care II (MIMIC II) database was analyzed. A cutoff value for 267.67 determined using Youden index (P < 0.05) used categorize...
Malnutrition has been associated with mortality in various diseases. This retrospective cohort study aimed to investigate the relationship between three nutritional indices and all-cause patients diabetic foot ulcers (DFUs). A total of 771 diagnosed DFUs First Affiliated Hospital Wenzhou Medical University from 2015 2019 were included this study. Patients classified as high risk groups or low according optimal cut-off values geriatric index (GNRI), prognostic (PNI), controlling status...