A5072354292- Analytical Chemistry and Chromatography
- Microfluidic and Capillary Electrophoresis Applications
- Advanced Proteomics Techniques and Applications
- Advanced biosensing and bioanalysis techniques
- Mass Spectrometry Techniques and Applications
- Colorectal Cancer Surgical Treatments
- Gastric Cancer Management and Outcomes
- Target Tracking and Data Fusion in Sensor Networks
- Hepatitis C virus research
- Innovative Microfluidic and Catalytic Techniques Innovation
- Inertial Sensor and Navigation
- Analytical chemistry methods development
- Hepatitis B Virus Studies
- Distributed Sensor Networks and Detection Algorithms
- Radiomics and Machine Learning in Medical Imaging
- Liver Disease Diagnosis and Treatment
- Glycosylation and Glycoproteins Research
- Protein purification and stability
- Cancer, Hypoxia, and Metabolism
- Metal-Organic Frameworks: Synthesis and Applications
- Microfluidic and Bio-sensing Technologies
- Chromatography in Natural Products
- Particle Accelerators and Free-Electron Lasers
- Monoclonal and Polyclonal Antibodies Research
- Electrochemical sensors and biosensors
East China University of Science and Technology
2016-2025
Lanzhou University Second Hospital
2011-2025
People's Hospital of Cangzhou
2025
Lanzhou University
2011-2025
University of California, San Francisco
2022-2024
Tokyo University of Science
2014-2024
Xiamen University
2024
Zhongshan Hospital of Xiamen University
2023-2024
First Affiliated Hospital of Henan University
2024
Affiliated Hospital of Guizhou Medical University
2024
In regard to the phosphoproteome, highly specific and efficient capture of heteroideous kinds phosphopeptides from intricate biological sample attaches great significance comprehensive in-depth phosphorylated proteomics research. However, until now, it has been a challenge. this study, new-fashioned porous immobilized metal ion affinity chromatography (IMAC) material was designed fabricated promote selectivity detection limit for by covering metal–organic frameworks (MOFs) shell onto Fe3O4...
The gut microbiome is involved in antitumor immunotherapy and chemotherapy responses; however, evidence-based research on the role of predicting response to neoadjuvant chemoradiotherapy (nCRT) patients with locally advanced rectal cancer (LARC) remains scarce. This prospective, longitudinal study aimed evaluate feasibility nCRT responses.We collected 167 fecal samples from 84 LARC before after 31 specimens healthy individuals for 16S rRNA sequencing. Patients were divided into responders...
Highly selective and efficient capture of glycosylated proteins peptides from complex biological samples is profound significance for the discovery disease biomarkers in systems. Recently, hydrophilic interaction liquid chromatography (HILIC)-based functional materials have been extensively utilized glycopeptide enrichment. However, low amount immobilized groups on affinity material has limited its specificity, detection sensitivity binding capacity glycopeptides. Herein, a novel was...
Infrared (IR) small target detection under complex environments is an essential part of IR search and track systems. However, previously proposed algorithms cannot achieve complete suppression significant backgrounds. The spatial–temporal information image sequences not fully exploited. In this article, we present a sparse regularization-based twist tensor model for detection. First, the built via perspective conversion based on target's local continuity in domain, which makes original...
Magnetic nanoparticles (MNPs) coated with multilayer polysaccharide shells have been fabricated using a layer-by-layer approach via the alternate deposition of hyaluronan (HA) and chitosan (CS) onto surface, hydrophilic materials were utilized for effective selective enrichment glycopeptides in biological samples.
Abstract Facile preparation of core–shell magnetic metal–organic framework nanospheres by a layer‐by‐layer approach is presented. The have high surface area (285.89 cm 2 g −1 ), large pore volume (0.18 3 two kinds mesopores (2.50 and 4.72 nm), excellent responsivity (55.65 emu structural stability, good dispersibility. combination porosity, hydrophobicity, uniform magnetism was exploited for effective enrichment peptides with simultaneous exclusion molecular weight proteins. were...
Lanthanide coordination polymers have been recently regarded as attractive sensing materials because of their selectivity, high sensitivity, and rapid response ability. In this research, the multiporous terbium phosphonate polymer microspheres (TbP-CPs) were prepared a novel fluorescent probe, which showed fluorescence turn-on capability for detection trace anthrax biomarker dipicolinate acid (DPA). The morphology chemical composition as-prepared TbP-CPs characterized in detail....
During the fast switching in Ge2Sb2Te5 phase change memory devices, both amorphous and fcc crystalline phases remain metastable beyond hexagonal transition temperatures respectively. In this work, electrical properties together with crystallization times resistance drift behaviour of GST are studied using a high-speed, device-level characterization technique temperature range 300 K to 675 K.
A novel magnetic polymer nanoparticle (Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub>@(HA/CS)<sub>10</sub>–Ti<sup>4+</sup> IMAC) was synthesized for the highly selective and efficient enrichment of phosphopeptides.
A simple and effective preconcentration method based on magnetic core–shell silica nanoparticles with C 18 ‐modified surface was developed for the analysis of pesticide residues in environmental water samples by gas chromatography‐mass spectrometry. Several kinds organophosphorous pyrethroid pesticides including methamidophos, dichlorvos, orthene, phorate, dimethoate, carbofuran, bifenthrin, fenpropathrin, cypermethrin, fenvalerate, deltamethrin were used as model compounds to systematically...
The highly selective and efficient capture of heterogeneous types phosphopeptides is critical for comprehensive in-depth phosphoproteome analysis, but it still remains a challenge since the lack affinity material with large binding capacity controllable specificity. Here, new was prepared to improve enrichment endue tunable specificity by introducing guanidyl onto poly(glycidyl methacrylate) (PGMA) modified Fe3O4 microsphere (denoted as Fe3O4@PGMA-Guanidyl). thick polymer shell endows...
This paper presents a mixed-initiative tool for multiobjective planning and asset routing (TMPLAR) in dynamic uncertain environments. TMPLAR is built upon programming algorithms to route assets timely fashion, while considering fuel efficiency, voyage time, distance, adherence real world constraints (asset vehicle limits, navigator-specified deadlines, etc.). has the potential be applied variety of contexts, including ship, helicopter, or unmanned aerial routing. The provides recommended...
Although many molecules have been investigated as biomarkers for spinal cord injury (SCI) or ischemic stroke, none of them are specifically induced in central nervous system (CNS) neurons following injuries with low baseline expression. However, neuronal constitutes a major pathology associated SCI stroke and strongly correlates neurological outcomes. Biomarkers characterized by expression specific induction post-injury likely to better correlate severity recovery, demonstrating higher...
Lupeol (Lup-20(29)-en-3H-ol), a novel dietary triterpene, was found in fruits, vegetables, and several medicinal plants. Here, we investigated its growth-inhibitory effect associated mechanisms hepatocellular carcinoma SMMC7721 cells. treatment resulted significant inhibition of cell viability dose-dependent manner caused apoptotic death this line with activation caspase3 expression. Caspase8 inhibitor pretreatment to partially block the apoptosis induced by Lupeol. Moreover, specifically...