- Intracranial Aneurysms: Treatment and Complications
- Vascular Malformations Diagnosis and Treatment
- Glioma Diagnosis and Treatment
- Head and Neck Surgical Oncology
- Radiopharmaceutical Chemistry and Applications
- Oral and Maxillofacial Pathology
- Electron and X-Ray Spectroscopy Techniques
- Cerebral Venous Sinus Thrombosis
- Botulinum Toxin and Related Neurological Disorders
- Bone Tumor Diagnosis and Treatments
- Cerebrospinal fluid and hydrocephalus
- Salivary Gland Tumors Diagnosis and Treatment
- Pituitary Gland Disorders and Treatments
- Neurofibromatosis and Schwannoma Cases
- RNA Interference and Gene Delivery
- Meningioma and schwannoma management
- Facial Nerve Paralysis Treatment and Research
- Neurosurgical Procedures and Complications
- Trigeminal Neuralgia and Treatments
- Nuclear Structure and Function
- Toxoplasma gondii Research Studies
- Electrochemical sensors and biosensors
- Thyroid and Parathyroid Surgery
- Oropharyngeal Anatomy and Pathologies
- Advanced Electron Microscopy Techniques and Applications
Showa University
1985-2021
Showa University Koto Toyosu Hospital
2020-2021
Showa University Fujigaoka Hospital
2018-2021
Ebara Hospital
2019-2020
Riverside Methodist Hospital
2020
OhioHealth
2020
Toho University
2018
Tokyo Women's Medical University
2015
Osaka National Hospital
2011
Fukushima Medical University
2011
Extensive molecular analyses of ependymal tumors have revealed that supratentorial and posterior fossa ependymomas distinct profiles are likely to be different diseases. The presence C11orf95-RELA fusion genes in a subset (ST-EPN) indicated the existence subgroups. However, pathogenesis RELA fusion-negative remains elusive. To investigate these validate classification tumors, we conducted thorough 113 locally diagnosed from 107 patients Japan Pediatric Molecular Neuro-Oncology Group. All...
Background Pandemic influenza A(H1N1) virus infection quickly circulated worldwide in 2009. In Japan, the first case was reported May 2009, one month after its outbreak Mexico. Thereafter, spread widely throughout country. It is of great importance to profile and understand situation regarding viral mutations their circulation Japan accumulate a knowledge base prepare clinical response platforms before second pandemic (pdm) wave emerges. Methodology A total 253 swab samples were collected...
Classical NMDA receptors (NMDARs), activated by glycine and glutamate, are heteromultimers comprised of NR1 NR2 subunits. Coexpression the novel NR3 family NMDAR subunits decreases magnitude NR1/NR2 receptor-mediated currents or forms glycine-activated channels with subunit alone. The second (M2) third (M3) membrane segments classical NMDARs form core channel permeation pathway. Structural information regarding NR1/NR3 remains unknown. Using Xenopus oocyte expression system SCAM (substituted...
Botulism, very rare disease as it is, has long been reported in Europe and America, although no report referring to occurrence of this had presented Japan prior 1952, when Nakamura, Iida Saeki an outbreak type E botulism at Iwanai, Hokkaido, due herring-izushi. In the following year, another two outbreaks izushi involving fish were by same authors. Again, early October, 1953, authors learned fourth Hokkaido.Incidentally, concurrently with fouth four persons a family Tenno, small town upon...
Objectives: Orbitofrontal fibrous dysplasia often involves the bony orbit and optic canal. Although reportedly produces compression of nerve leading to visual disturbances, decompression in patients without clinical signs neuropathy remains controversial. We describe recent development surgical techniques equipment for orbitofrontal dysplasia. Methods: Optic was performed prophylactically five therapeutically one patient using transcranial extradural route. A high-speed drill continuous...
Hemodialysis (HD) patients are reported to show poor clinical outcomes after percutaneous coronary intervention (PCI) with sirolimus-eluting stent (SES) compared non-HD and their long-term prognosis remains unclear.We prospectively enrolled 489 consecutive undergoing PCI SES performed a retrospective analysis focusing on HD patients. Median follow-up was 7.0 years (interquartile range, 4.2-7.9) the rate 100%. At 7-year follow-up, cumulative incidences of all-cause death, target lesion...
Objectives In microvascular decompression (MVD) for hemifacial spasm (HFS), the patient is placed in lateral or park-bench position that complicated and uncomfortable anesthesiologists, nurses, even patient. Careless retraction of cerebellum by a spatula could be major cause surgical complications. our method, laid supine avoiding positioning. The subfloccular approach from small cranial window sited on more basal side occipital cranium enables surgeon to reach all segments facial nerve root...
It has been the accepted opinion that there are one million nerve fibres in human medullary pyramid. This seemed to be confirmed several old reports. But we cannot agree with this opinion. We made nitrocelluloseembedded sections from three normal male brains, and stained them by our modification of Masson-Goldner method. With method, myelinated axons appeared blue, whereas glial processes were coloured red. which allowed easy discrimination between two. After morphometric evaluation...
A 42-year-old male presented with a rare extracranial meningioma manifesting as right facial swelling, nerve paresis, and hearing disturbance. Neurological imaging revealed primarily extra-axial tumor extending from the temporal base to subcutaneous space in parietal region, partially into intra-axial region of lobe through dura mater, small intracerebral hematoma mass porus acusticus destroying bone, floor middle fossa, zygomatic arch, acusticus. Malignant was confirmed by histological...
Recent studies have shown that fibroblast growth factor-23 (FGF-23) is elevated not only in chronic kidney disease (CKD), but also acute illnesses such as injury, septic shock, and heart failure. FGF-23 would be a simple biomarker direct toxic factor illness. Therefore, lowering circulating levels clinical practice an exciting valuable interventional strategy. Continuous hemodiafiltration (CHDF) often performed for the treatment of aforementioned illnesses. We previously reported...
Unmyelinated nerve fibers of the oculomotor have occasionally been observed in experimental animals with use electron microscopes, but no details concerning normal nerves humans published. We measured and analyzed unmyelinated human an image analyzer a computer, using new staining method, Luxol fast blue-periodic acid-Schiff-hematoxylin (LPH) discriminative method which is only one suitable for morphometric research on nervous tissues. studied numbers transverse areas 20 cadavers. The number...
Objective: We could cure two cases of arteriovenous fistula (AVF) the scalp by pressure cooker technique (PCT).
Objective: The objectives of treating dural arteriovenous fistula (dAVF) are to achieve complete occlusion the (AV) shunt and restoration anterograde venous flow. We report a patient with complex dAVF who was managed by double overinflated balloon protection torcula percutaneous transluminal angioplasty (PTA) for occluded sinus.
The acoustic brain has the ability to detect deviant sounds in series of homogeneous sounds. mismatch negativity (MMN) is considered reflect this ability. Various types deviations including omission sound can elicit MMN. MMN generated by comparison process between change and memory trace preceding stored sensory memory. When formed memory, mechanism termed temporal window integration (TWI) which integrates closely presented into single units activated. provided evidence for presence TWI...
Six cases of lingual mandibular bone concavity are reported in this paper with review the literature. This is usually seen between canal and inferior border mandible, just anterior to angle. condition also portion mandible.A variety terms have been applied concavity, including static cavity, defect, latent cyst, idiopathic aberrant salivary gland tissue developmental so on. Recently, term, thought express most precisely. Since Stafne described 1942, numerous English In Japan, however, only...
Abstract CXCR4 is both a chemokine receptor and an entry co-receptor for the T-cell line-adapted human immunodeficiency virus type 1 (HIV-1). To find more efficacious therapeutic treatement of acquied syndrome, we exmined effects antisense oligonucleotides on production. COS cells, stably expressing CD4, were incubated with several kinds oligonucleotides. Total p24 antigen production was determined using enzyme-linked immunosorbent assay system. An phosphorothioate-modified oligonucleotide,...