A5089437929- Evaluation and Optimization Models
- Advanced Decision-Making Techniques
- Vibration Control and Rheological Fluids
- Asthma and respiratory diseases
- Evaluation Methods in Various Fields
- Plant tissue culture and regeneration
- Allergic Rhinitis and Sensitization
- Photonic and Optical Devices
- Seismic Performance and Analysis
- Prenatal Screening and Diagnostics
- Vehicle Dynamics and Control Systems
- Respiratory and Cough-Related Research
- Research studies in Vietnam
- Synthesis and Biological Evaluation
- Plant Molecular Biology Research
- Orbital Angular Momentum in Optics
- Chemical Synthesis and Reactions
- Plant biochemistry and biosynthesis
- Optical Network Technologies
- Pediatric health and respiratory diseases
- Photosynthetic Processes and Mechanisms
- Vanadium and Halogenation Chemistry
- Advanced Computational Techniques and Applications
- Advanced Photonic Communication Systems
- Microbial Metabolism and Applications
First Affiliated Hospital of Guangzhou Medical University
2018-2025
State Key Laboratory of Respiratory Disease
2018-2025
Guangzhou Medical University
2018-2025
Guangdong University of Technology
2021-2024
Nanjing Drum Tower Hospital
2011-2024
Chinese Academy of Sciences
2005-2023
Nanyang Technological University
2019-2023
National Clinical Research
2021
Second Affiliated Hospital of Zhengzhou University
2019
Nanjing Forestry University
2019
To the Editor, Allergen sensitization occurs in most patients with asthma. Our previous article had demonstrated that house dust mite remained important allergen Chinese individuals asthma.1 A raised serum IgE against Aspergillus antigens usually occurred bronchial asthma, especially a value ≥1000 IU/mL was recommended as total (tIgE) cut-off to diagnose Allergic bronchopulmonary aspergillosis (ABPA).2 Therefore, we aim describe prevalence of common allergens among asthmatic tIgE >1000...
Low temperature is one of the most important environmental factors that limits geographical distribution and productivity grapevine. However, molecular mechanisms on how grapevine responds to cold stress remains be elucidated. MicroRNAs (miRNAs) are a class endogenous small non-coding RNAs play an essential role during plant development responses. Although miRNAs their targets have been identified in several Vitis species, participation accumulation unknown. In this study, two RNA libraries...
With the rapid growth of aquaculture globally, large amounts antibiotics have been used to treat aquatic disease, which may accelerate induction and spread antibiotic-resistant bacteria (ARB) antibiotic resistance genes (ARGs) in environments. Herein, metagenomic 16S rRNA analyses were analyze potentials co-occurrence patterns pathogenome (culturable unculturable pathogens), resistome (ARGs), mobilome (mobile genetic elements (MGEs)) from mariculture waters near 5000 km coast South China....
Little is known about the changes in allergen sensitization China secondary to environmental variations over past decade. We aimed at investigating among asthma and/or rhinitis patients between 2008 and 2018.This study analyzed cross-sectional data from national surveys conducted 2018. After finishing questionnaire, participants underwent serum specific IgE measurements. A total of 2322 2798 were enrolled 2018, respectively. The significance differences rates four regions assessed....
Acid inhibitors have been considered in treating gastroesophageal reflux-related cough (GERC). Compared to proton pump (PPIs), potassium-competitive acid blockers (P-CABs) more potent and durable effects on anti-acid secretion. However, whether vonoprazan esomeprazole different therapeutic GERC remains unknown. Patients diagnosed with were enrolled our study randomly treated (20 mg, once daily, P-CAB) or twice PPI) for two months. A prokinetic agent was also administered. followed up a...
Abstract Epithelial cells play a crucial role in asthma, contributing to chronic inflammation and airway hyperresponsiveness. m6A modification, which involves key proteins such as the demethylase fat mass obesity‐associated protein (FTO), is regulation of various diseases, including asthma. However, FTO epithelial development asthma remains unclear. In this study, we investigated activity using small‐molecule inhibitor FB23 allergic vivo vitro. We examined FTO‐regulated transcriptome‐wide...
Myeloid-derived suppressor cells (MDSCs) participate in the progression of many diseases including chronic lung diseases. However, whether MDSCs are accumulated and how orchestrate pulmonary microenvironment bronchiectasis remains unknown. Here, we aim to test a hypothesis that PMN-MDSCs play role creating an airway immunosuppressive milieu, thereby relating clinical outcomes bronchiectasis. Flow cytometry immunofluorescence staining were performed for analysing frequencies presence...
Background: Allergic diseases are a growing health concern, with house dust mites being prevalent allergen linked to various allergies. Rush subcutaneous immunotherapy (RIT) achieves maintenance dose rapidly but carries higher risks than conventional (CIT). The combination of Omalizumab (AIT) has been shown improve AIT safety. This study investigates the safety RIT combined anti-immunoglobulin E (IgE) pretreatment. Methods: retrospective analysis compared patients allergic rhinitis and/or...
Abstract Heteroaromatic sulfoxides, especially 1 H ‐benzimidazolylpyridinylmethyl usually used as the blockbuster gastric proton pump inhibitors (PPIs), have been prepared highly enantioselectivily by catalytic asymmetric oxidation of sulfides attached to nitrogen‐containing heterocyles with tert ‐butyl hydroperoxide in presence a chiral titanium complex, formed situ from Ti( i PrO) 4 , 1,2‐diphenylethane‐1,2‐diol 3c and water. The sufoxides were obtained high yield (97 %) excellent...
Cysteine proteinase inhibitor (cystatin, CPI) is one of the most important molecules involved in plant development and defense, especially regulation stress responses. However, it still unclear whether Jatropha curcas CPI (JcCPI) gene functions salinity response tolerance. In this study, sequence JcCPI gene, its expression pattern, effects overexpression Escherichia coli Nicotiana benthamiana were examined. The purpose study was to evaluate regulatory role designated JcCPI, cloned from J....
The scintillation of the orbital angular momentum (OAM) a Bessel Gaussian beam was derived based on Rytov method to characterize performance OAM communication. Moreover, multi-parameter demultiplexing also proposed which could decode state, amplitude and two additional width information dimensions. advantages states as communication carrier over intensity were that minimum fundamental mode smaller, its corresponding radius diverged slower. coefficient variation decoding approximated square...
Interleukin (IL)‐1 is markedly overexpressed in the brains of patients with Alzheimer's disease (AD). We aimed to evaluate relationship between three polymorphisms IL1 gene (IL‐1beta promoter −511T/C, IL‐1beta exon 5 E1/E2 and IL‐1‐RA) late onset AD Taiwan Chinese. Forty‐six 103 unrelated, age‐matched, healthy controls living same area were included. PCR was used resolve two IL‐1Ra intron 2 polymorphism. The −511T/T type (unlike more frequently found than (−511C/C versus T/T type, OR =...
To investigate the clinical value of chromosomal microarray analysis (CMA) in prenatal diagnosis genetic abnormalities fetal isolated mild ventriculomegaly.This retrospective study reviewed 101 fetuses with ventriculomegaly who had undergone invasive at our hospital. CMA was performed all cases to detect aneuploidy as well copy number variations (CNVs) that are too small be detected by conventional karyotyping. Real time quantitative PCR (qPCR) or multiplex ligation dependent probe...
High-sensitivity C-reactive protein (hs-CRP) is not only a marker of inflammation but also prognostic factor for ischemic stroke. The objective our study was to investigative the association between hs-CRP levels and outcomes patients with small-artery occlusion (SAO).We selected 718 participants diagnosed SAO (according Trial Org 10172 in Acute Stroke Treatment classification) using stroke registry Department Neurorehabilitation Tianjin HuanHu Hospital. Hs-CRP values at admission were...
Abstract A cDNA library generated from seeds of Cassia obtusifolia was sequenced using Illumina/Solexa platform. More than 12,968,231 high quality reads were generated, and have been deposited in NCBI SRA (SRR 1012912). total 40,102 unigenes (>200 bp) obtained with an average sequence length 681 bp by de novo assembly. About 34,089 (85%) unique sequences annotated 8694 the assigned to specific metabolic pathways Kyoto Encyclopedia Genes Genomes. Among them, 131 unigenes, which are...
Background: An elevated plasma total homocysteine (tHcy) level is an independent risk factor for vascular events. The aim of the present study was to investigate association between tHcy levels in acute phase cerebral infarction and functional outcome among elderly patients. Methods: Between October 2009 December 2012, we recruited 594 patients (age > 75) with first-onset who were consecutively admitted Department Neurology Tianjin Huanhu Hospital, China. Levels other biochemical values...
The 2 <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$\mu \text{m}$ </tex-math></inline-formula> waveband, specifically near notation="LaTeX">$1.9~\mu , is an imperative resource that could possibly be exploited in future communications systems. This due to the promising infrastructural developments at wavelength region (hollow-core photonic bandgap fiber, thulium-doped fiber amplifier) . In this work, we...
Background The results of skin and blood allergen testing are not consistently relevant to clinical manifestations in allergic patients. Objective aim the study was investigate relationship between severity rhinitis different diagnostic tests Dermatophagoides species-sensitized Methods Study subjects included 65 patients—50 with pteronyssinus (DP) sensitization (DP+) 15 without DP (DP−), DP+ 37 DP− healthy controls (HCs) confirmed by prick (SPT) specific immunoglobulin E (sIgE) tests....