A5101688860- Toxic Organic Pollutants Impact
- Per- and polyfluoroalkyl substances research
- MicroRNA in disease regulation
- RNA modifications and cancer
- Birth, Development, and Health
- Cancer-related molecular mechanisms research
- Effects and risks of endocrine disrupting chemicals
- COVID-19 Clinical Research Studies
- Analytical Chemistry and Sensors
- Ferroptosis and cancer prognosis
- Advanced Chemical Sensor Technologies
- RNA Interference and Gene Delivery
- Long-Term Effects of COVID-19
- SARS-CoV-2 and COVID-19 Research
- Gas Sensing Nanomaterials and Sensors
- Autophagy in Disease and Therapy
- RNA Research and Splicing
- Nuclear Receptors and Signaling
- Calcium signaling and nucleotide metabolism
- Circular RNAs in diseases
- Reproductive biology and impacts on aquatic species
- Tissue Engineering and Regenerative Medicine
- Chaos-based Image/Signal Encryption
- Microplastics and Plastic Pollution
- RNA regulation and disease
Xiamen University
2024
Guizhou Provincial People's Hospital
2015-2023
Harbin Medical University
2021-2023
Heilongjiang University
2023
Jiangxi Agricultural University
2022-2023
Zhejiang University of Technology
2020-2022
Jiangxi Academy of Sciences
2019-2022
Jiangxi University of Technology
2022
Fujian Provincial Cancer Hospital
2020-2022
Fujian Medical University
2020-2022
The novel PFOS alternatives, 6:2 chlorinated polyfluorinated ether sulfonate (F-53B) and sodium p-perfluorous nonenoxybenzenesulfonate (OBS), are emerging in the Chinese market, but little is known about their ecological risks. In this study, zebrafish embryos were exposed to PFOS, F-53B, OBS evaluate bioconcentration acute metabolic consequences. Per- polyfluoroalkyl substances (PFASs) accumulated larvae order of F-53B > OBS, with factors ranging from 20 357. Exposure not increased energy...
Several per- and polyfluoroalkyl substances (PFAS) have been linked to metabolic disorders in organisms. However, few studies considered their combined effects, which would be more representative of PFAS occurring the environment. In this study, zebrafish embryos were exposed a mixture 18 at three environmentally relevant concentrations for 5 days assess bioconcentration consequences. The burdens ∑PFAS larvae 0.12, 1.58, 9.63 mg/kg 0.5, 5, 50 μg/L treatment groups, respectively. Exposure...
Metformin has been shown to inhibit the proliferation and migration of vascular wall cells. However, mechanism through which metformin acts on atherosclerosis (AS) via long non-coding RNA taurine up-regulated gene 1 (lncRNA TUG1) is still unknown. Thus, this research investigated effect lncRNA TUG1 AS.First, qRT-PCR was used detect expression in patients with coronary heart disease (CHD). Then, correlation between vitro their effects proliferation, migration, autophagy cells were examined....
Abstract To find out the role of hsa‐miR‐570‐3p targeting CD274 in triple negative breast cancer (TNBC) via PI3K/AKT/mTOR signaling pathway. Hsa‐miR‐570‐3p and expressions 175 TNBC patients were detected by qRT‐PCR immunohistochemistry respectively. The human cell lines (MDA‐MB‐468 MDA‐MB‐231) used to verify relationship between dual‐luciferase reporter gene assay. Then, MDA‐MB‐468 MDA‐MB‐231 cells divided into Blank, miR‐NC, miR‐570‐3p mimics, NC siRNA, inhibitors + siRNA groups. Next,...
Parkinson's disease (PD), a common multifactorial neurodegenerative disease, is characterized by irreversible loss of dopaminergic neurons in the substantia nigra. In‑depth study pathogenesis PD great importance. High‑mobility group AT‑hook 2 (HMGA2) has been proposed to be implicated with neuronal differentiation and impairment cognitive function. However, whether HMGA2 plays role rarely explored. In present study, N‑methyl‑4‑phenyl‑1,2,3,6‑tetrahydropyridine (MPTP)‑treated mice models...
Breast cancer (BRCA) has become the most frequently appearing, lethal, and aggressive with increasing morbidity mortality. Previously, it was discovered that HAUS5 protein is involved in centrosome integrity, spindle assembly, completion of cytoplasmic division process during mitosis. By encouraging chromosome misdivision aneuploidy, potential to cause cancer. The significance BRCA relationship between its expression clinical outcomes or immune infiltration remains unclear.Pan-cancer...
Abstract Apoptosis of vascular endothelial cells (VECs) is highly important in the occurrence and development atherosclerosis (AS). HomeboxC6 (HOXC6) expressed higher levels multiple malignant tissues, it influences biological behavior cancer cells. However, effects HOXC6 on AS apoptosis VECs have not been fully elucidated. In this study, we demonstrated that expression was increased aortic wall rats peripheral blood monocytes patients with coronary heart disease. Furthermore, uncovered BAX...
Induction of cardiomyocyte (CM) proliferation is a promising approach for cardiac regeneration following myocardial injury. MicroRNAs (miRs) have been reported to regulate CM proliferation. In particular, miR‑449a‑5p has identified be associated with in previous high throughput functional screening data. However, whether regulates not thoroughly investigated. This study aimed explore modulates and identify the molecular mechanism via which The current demonstrated that expression levels were...
Numerous studies have shown that long noncoding RNAs (lncRNAs) play essential roles in the development and progression of human cardiovascular diseases. However, whether lncRNA ezrin antisense RNA 1 ( EZR-AS1 ) is associated with coronary heart disease (CHD) remains unclear. Accordingly, aim present study was to evaluate role patients CHD venous endothelial cells (HUVECs). The findings revealed highly expressed peripheral blood CHD. In vitro experiments showed overexpression could enhance...
Autophagy, a stress response in eukaryotic cells, is closely related to cardiogenic diseases. Pyroptosis, newly discovered way of programmed cell death, also plays an important role cardiovascular disease. However, the and relationship autophagy pyroptosis lipopolysaccharide (LPS)-induced inflammatory cardiomyocytes were still unclear.Western blot was performed determine expression poly ADP-ribosepolmesera-1 (PARP-1), LC3B, NLRP3 GSDMD after treatment LPS. Transfection si-LC3B, western...
Image encryption is distinct from text encryption. This difference can be attributed to the fact that an image consists of a large amount data, thereby resulting in low efficiency real-time In this paper, we propose novel scheme for secure transmission. A method applied using optical computing technologies which inherently deal with images and massive amounts data parallel, so attain purpose high speed. The implemented by stream cipher through polarization-encoding functioned as logic gates....
Homeobox c6 (Hoxc6) affects the proliferation, migration, and infiltration of malignant tumor cells; however, effect Hoxc6 on atherosclerosis (AS) as well proliferation migration vascular smooth muscle cells (VSMCs), which play a role in promoting AS, has not yet been clarified. In present study, we tested hypothesis that rat VSMCs, hence is involved AS. The results showed expression mRNA protein was higher normal aortic wall than myocardium. Subsequently, model AS established by high-fat...
Abstract Background: Previous studies have focused on the clinical characteristics of hospitalized patients with novel 2019 coronavirus disease (COVID-19). Limited data are available for convalescent patients. This study aimed to evaluate discharged COVID-19 Methods: In this retrospective study, we extracted 134 in Guizhou Provincial Staff Hospital from February 15 March 31, 2020. Cases were analyzed basis demographic, clinical, and laboratory as well radiological features. Results: Of...
Abstract Despite the substantial progress in deciphering pathogenesis of atherosclerosis (AS), cardiovascular mortality is still increasing. Therefore, atherosclerotic disease remains a sweeping epidemic that jeopardizes human health. Disentangling molecular underpinnings AS imperative cardiology field. Overwhelming evidence has indicated recognition fascinating class players, known as long non-coding RNAs (lncRNAs), provides causality for coordinating AS. However, function and mechanism...