A5078508839- Advanced X-ray and CT Imaging
- Vascular Procedures and Complications
- Radiomics and Machine Learning in Medical Imaging
- Peripheral Artery Disease Management
- Radiation Dose and Imaging
- Medical Imaging Techniques and Applications
- Cardiac Imaging and Diagnostics
- Blood Pressure and Hypertension Studies
- Ultrasound in Clinical Applications
- Coronary Interventions and Diagnostics
- Aortic aneurysm repair treatments
- Ultrasound and Hyperthermia Applications
- Prostate Cancer Diagnosis and Treatment
- Colorectal Cancer Screening and Detection
- Cardiac, Anesthesia and Surgical Outcomes
- Infectious Aortic and Vascular Conditions
- Advanced MRI Techniques and Applications
- Reconstructive Surgery and Microvascular Techniques
- Electrospun Nanofibers in Biomedical Applications
- Cardiac tumors and thrombi
- Atrial Fibrillation Management and Outcomes
- MRI in cancer diagnosis
- Aortic Disease and Treatment Approaches
- Multiple Myeloma Research and Treatments
- Coronary Artery Anomalies
General University Hospital in Prague
2016-2025
Charles University
2016-2025
University Hospital in Motol
2025
Technical University of Liberec
2022
Ocní klinika
2017
University Hospital Kralovske Vinohrady
2015-2016
Nemocnice Podlesí
2016
University Hospital Olomouc
2016
Beaumont Hospital
2015
Friedrich-Alexander-Universität Erlangen-Nürnberg
1979
Pancreatic ductal adenocarcinoma (PDAC), the most deadly solid malignancy, is typically detected late and at an inoperable stage. Early or incidental detection associated with prolonged survival, but screening asymptomatic individuals for PDAC using a single test remains unfeasible due to low prevalence potential harms of false positives. Non-contrast computed tomography (CT), routinely performed clinical indications, offers large-scale screening, however, identification non-contrast CT has...
BACKGROUND Whole-body magnetic resonance imaging (wbMRI) allows general assessment of systemic cancers including lymphomas without radiation burden. AIM To evaluate the diagnostic performance wbMRI in staging diffuse large B-cell lymphoma (DLBCL), determine value individual MRI sequences, and assess patients’ concerns with wbMRI. METHODS In this single-center prospective study, adult patients newly diagnosed DLBCL underwent on a 3T scanner [diffusion weighted images background suppression...
This randomized, multicenter study compared the relative efficacy of renal denervation (RDN) versus pharmacotherapy alone in patients with true resistant hypertension and assessed effect spironolactone addition. We present here 12-month data. A total 106 were enrolled this study: 52 randomized to RDN 54 addition, baseline systolic blood pressure 159±17 155±17 mm Hg average number drugs 5.1 5.4, respectively. Twelve-month results are available 101 patients. The intention-to-treat analysis...
Iron accumulates in brain tissue healthy subjects during aging. Our goal was to conduct a detailed analysis of iron deposition patterns the cerebral deep grey matter and cortex using region-based whole-brain analyses magnetic susceptibility.Brain MRI performed 95 individuals aged between 21 58 years on 3T scanner. protocol included T1-weighted (T1W) magnetization-prepared rapid acquisition with gradient echo images 3D flow-compensated multi-echo gradient-echo for quantitative susceptibility...
Martin Jurka, Iva Macova, Monika Wagnerova, Otakar Capoun, Roman Jakubicek, Petr Ourednicek, Lukas Lambert, Andrea Burgetova
Budd-Chiari syndrome (BCS) is a rare disease with an incidence of 0.1 to 10 per million inhabitants year caused by impaired venous outflow from the liver mostly at level hepatic veins and inferior vena cava. Etiological factors include hypercoagulable conditions, myeloprolipherative diseases, anatomical variability cava, environmental conditions. Survival rates in treated patients range 42 100% depending on etiology presence risk including parameters Child-Pugh score, sodium creatinine...
The primary objective of the present prospective study was to compare diagnostic performance conventional radiography (CR) and whole-body low-dose computed tomography (WBLDCT) with a comparable radiation dose reconstructed using hybrid iterative reconstruction technique, in terms detection bone lesions, skeletal fractures, vertebral compressions extraskeletal findings. secondary evaluate lesion attenuation relation its size. A total 74 patients underwent same-day survey by CR WBLDCT. In...
Maternally inherited complex I deficiencies due to mutations in MT-ND genes represent a heterogeneous group of multisystem mitochondrial disorders (MD) with unfavourable prognosis. The aim the study was characterize impact genes, including novel m.13091 T > C variant, on course disease, and analyse activities respiratory chain complexes, amount protein subunits, energy-generating system (MEGS) available muscle biopsies cultivated fibroblasts.The were measured by spectrophotometry, MEGS...
<h3>Background</h3> In addition to the diagnostic accuracy of imaging methods, patient-reported satisfaction with methods is important. <h3>Objective</h3> To report a secondary outcome prospective international multicenter Imaging Study in Advanced ovArian Cancer (ISAAC Study), detailing patients' experience abdomino-pelvic ultrasound, whole-body contrast-enhanced computed tomography (CT), and diffusion-weighted magnetic resonance (WB-DWI/MRI) for pre-operative ovarian cancer work-up....
The randomized, multicentre study compared the efficacy of renal denervation (RDN) versus spironolactone addition in patients with true resistant hypertension. We present 24-month data.A total 106 hypertension were enrolled this study: 52 randomized to RDN and 54 addition, baseline SBP 159 ± 17 155 mmHg average number drugs 5.1 5.4, respectively. Two-year data are available 86 patients. Spironolactone as crossover after 1 year, was performed 23 RDN, followed by five patients.Similar...
Introduction: Cathodal transcranial direct current stimulation (C-tDCS) is a potential neuroprotective method in the hyperacute phase of ischemic stroke. In rodent models, C-tDCS reduced final infarct volume and improved functional outcome. Our aim was to assess safety, tolerability, feasibility, efficacy stroke patients with salvageable penumbra. Methods: study single-center, double-blind, randomized, sham-controlled (3 active: 1 sham), 3+3 dose-escalation trial. Inclusion criteria were due...
The diagnostic accuracy of prostate magnetic resonance imaging (MRI) is highly dependent on image quality. Although the effects spasmolytics and rectal preparation have been previously studied, findings remain inconsistent fail to address other critical modifiable factors. This study aimed evaluate impact various factors MRI quality their subsequent influence Prostate Imaging Reporting Data System (PI-RADS) scoring. Fifty-six consecutive patients who underwent 3T multiparametric (mpMRI) with...
Abstract Objectives This study aims to assess the accuracy of generative pre-trained transformer 4o (GPT-4o) in answering multiple response questions from European Diploma Radiology (EDiR) examination, comparing its performance that human candidates. Materials and methods Results 42 EDiR candidates across Europe were compared those 26 fourth-year medical students who answered exclusively using ChatGPT-4o a prospective (October 2024). The challenge consisted 52 recall or understanding-based...
Computed tomography (CT) colonography is a well established modality for the examination of symptomatic patients as in screening. Recent technical advances improving image quality by iterative reconstruction contribute to reduction radiation dose which major concern CT imaging.To evaluate ultralow-dose submilisievert using hybrid technique.Sixteen underwent contrast-enhanced with standard protocol supine position and prone position. Ultralow-dose datasets were reconstructed filtered back...
Extracorporeal membrane oxygenation (ECMO) is an established tool for respiratory and circulatory support. In computed tomography, altered hemodynamics in ECMO patients requires special considerations handling contrast injection its timing. this article, we demonstrate changes captured on contrast-enhanced CT examinations pitfalls strategies relation to the flow, cardiac function placement of cannulas. Contrast-enhanced with prior knowledge cannulas, central venous lines, induced by low...