A5078612962- Cardiac, Anesthesia and Surgical Outcomes
- Organ Transplantation Techniques and Outcomes
- Transplantation: Methods and Outcomes
- Trauma and Emergency Care Studies
- Pediatric Hepatobiliary Diseases and Treatments
- Cardiac Arrest and Resuscitation
- Breast Implant and Reconstruction
- Global Cancer Incidence and Screening
- Healthcare Policy and Management
- Pancreatic and Hepatic Oncology Research
- Enhanced Recovery After Surgery
- Opioid Use Disorder Treatment
- Renal Transplantation Outcomes and Treatments
- Pelvic and Acetabular Injuries
- Nutrition and Health in Aging
- Lung Cancer Diagnosis and Treatment
- Vascular Procedures and Complications
- Bariatric Surgery and Outcomes
- Cardiac Valve Diseases and Treatments
- Gallbladder and Bile Duct Disorders
- Liver Disease and Transplantation
- Hospital Admissions and Outcomes
- Cardiac and Coronary Surgery Techniques
- Frailty in Older Adults
- BRCA gene mutations in cancer
University of California, Los Angeles
2023-2025
Core Laboratories (United States)
2023-2024
University of California, San Francisco
2024
UCSF Benioff Children's Hospital
2024
Oklahoma State University Center for Health Sciences
2023
E Ink (South Korea)
2022
Ohio Valley Medical Center
1964
Given the renewed interest in heart transplantation after donation circulatory death (DCD), a contemporary analysis of trends and longer-term survival is warranted.
ObjectiveGiven the nonelective nature of most trauma admissions, patients who experience are at a particular risk discharge against medical advice. Despite unplanned readmission and financial burden on health care system, advice among hospitalized continues to rise. The present study aimed assess evolving trends outcomes associated in with for traumatic injury.MethodsThe 2016–2020 Nationwide Readmissions Database was queried identify all hospitalizations injuries. patient cohort stratified...
ABSTRACT Introduction Frailty, a measure of physiological aging and reserve, has been validated as prognostic indicator mortality in patients with cirrhosis. However, large‐scale analyses the independent association frailty clinical financial outcomes following liver transplantation (LT) are lacking. Methods Adults (≥18 years) undergoing LT were identified 2016–2020 National Readmissions Database. Frailty was defined using binary Johns Hopkins Adjusted Clinical Groups indicator....
Background and Aims: Detailed investigation of the biological pathways leading to hepatic fibrosis identification liver biomarkers may facilitate early interventions for pediatric cholestasis. Approach Results: A targeted enzyme‐linked immunosorbent assay–based panel nine (lysyl oxidase, tissue inhibitor matrix metalloproteinase (MMP) 1, connective growth factor [CTGF], IL‐8, endoglin, periostin, Mac‐2–binding protein, MMP‐3, MMP‐7) was examined in children with biliary atresia (BA; n =...
Percutaneous cholecystostomy (PCT) is an alternative to cholecystectomy (CCY) in high-risk surgical candidates with severe acute cholecystitis. A subset of these patients ultimately undergo delayed CCY. We therefore compared outcomes CCY grade III cholecystitis who received a PCT on index admission, those did not.
This study aimed to identify microbial drivers of inflammatory bowel disease [IBD], by investigating mucosal-associated bacteria and their detrimental products in IBD patients. We directly cultured bacterial communities from mucosal biopsies paediatric gastrointestinal patients examined for pathogenicity-associated traits. Upon identifying Clostridium perfringens as toxigenic present biopsies, we isolated strains further characterized toxicity prevalence. Mucosal biopsy composition differed...
Background With a growing emphasis on value of care, understanding factors associated with rising healthcare costs is increasingly important. In this national study, we evaluated the degree center-level variation in cost spinal fusion. Methods All adults undergoing elective fusion were identified 2016 to 2020 National Inpatient Sample. Multilevel mixed-effect models used rank hospitals based risk-adjusted costs. The interclass coefficient (ICC) was utilized tabulate amount attributable...
Background Despite the favorable outcomes and safety profile associated with metabolic bariatric surgery (MBS), complications may occur post-operatively, necessitating emergency general (EGS) intervention. Objective To evaluate association of in patients prior MBS following EGS interventions Setting Academic, University-affiliated; USA. Methods All adults undergoing non-elective operations were identified using 2016 to 2020 Nationwide Readmission Database. Patients a history subsequently...
Objective: To assess the impact of community-level socioeconomic deprivation on survival outcomes following heart transplantation. Background: Despite growing awareness disparities in U.S. healthcare system, significant inequities remain. While recent literature has increasingly considered effects structural deprivation, community distress transplantation not yet been elucidated. Methods: All adult transplant recipients from 2004-2022 were ascertained Organ Procurement and Transplantation...
Early discharge after surgical procedures has been proposed as a novel strategy to reduce healthcare expenditures. However, national analyses of the association between timing and post-transplant outcomes following kidney transplantation are lacking.This was retrospective cohort study all adult transplant recipients without delayed graft function from 2014 2019 in Organ Procurement Transplantation Network Nationwide Readmissions Databases. Recipients were divided into (LOS ≤ 4 days), Routine...
Background: Off-pump coronary revascularization (OPCAB) has been proposed to benefit patients at greater surgical risk as it avoids the use of extracorporeal circulation. While historically older were considered high candidates, recent studies implicate frailty a more comprehensive measure perioperative fitness. Yet, outcomes OPCAB among frail have not elucidated. Thus, using national cohort patients, we assessed impact OPCAB, relative on-pump (ONCAB).Methods: Patients undergoing first-time,...
Alcohol withdrawal syndrome (AWS) presents with a complex spectrum of clinical manifestations that complicate postoperative management. In trauma setting, subjective screening for AWS remains challenging due to the criticality injury in these patients. We thus identified several patient characteristics and perioperative outcomes associated development.
ObjectiveThe number of adults with dementia is rising worldwide. Although has been linked inferior outcomes following various operations, this phenomenon not fully elucidated among patients undergoing elective lung resection. Using a national cohort, we evaluated the association clinical and financial lobectomy for cancer.MethodsAdults cancer were identified within 2010-2020 Nationwide Readmissions Database. Patients comorbid diagnosis considered Dementia cohort (others: Non-Dementia)....
o fCentral Message (199/200 characters) Frailty is associated with inferior outcomes in heart and lung transplantation.The inclusion of a frailty indicator may optimize targeted resource allocation intensive perioperative management. Central Image Abbreviated LegendFrailty status after transplantation.Perspective Statement (399/405 Frailty, characterized by decline physiological reserve resilience to stressors, has consistently demonstrated an association poorer clinical across various...
Minimally invasive resection for non-small cell lung cancer has been linked to decreased postoperative morbidity. This work sought characterize factors associated with receiving minimally surgery surgically resectable cancer.
With the growing opioid epidemic across US, in-hospital utilization of opioids has garnered increasing attention. Using a national cohort, this study sought to characterize trends, outcomes, and factors associated with overdose (OD) following major elective operations. We identified all adult (≥18 years) hospitalizations entailing select procedures in 2016–2020 National Inpatient Sample. Patients who experienced were characterized as OD (others: Non-OD). The primary outcome interest was OD....