A5043277278- Reproductive Physiology in Livestock
- Peroxisome Proliferator-Activated Receptors
- Ruminant Nutrition and Digestive Physiology
- Genetic and phenotypic traits in livestock
- Lipid metabolism and disorders
- Reproductive Biology and Fertility
- Cancer-related molecular mechanisms research
- Lipid metabolism and biosynthesis
- Cholesterol and Lipid Metabolism
- MicroRNA in disease regulation
- Liver Disease Diagnosis and Treatment
- Genomics, phytochemicals, and oxidative stress
- Animal Nutrition and Health
- Phytoestrogen effects and research
- Advanced machining processes and optimization
- Effects of Environmental Stressors on Livestock
- PI3K/AKT/mTOR signaling in cancer
- Metabolism, Diabetes, and Cancer
- Pregnancy-related medical research
- Ginseng Biological Effects and Applications
- Gear and Bearing Dynamics Analysis
- Animal health and immunology
- Collagen: Extraction and Characterization
- Diabetic Foot Ulcer Assessment and Management
- Protein Hydrolysis and Bioactive Peptides
Heilongjiang Bayi Agricultural University
2010-2024
Shenzhen Children's Hospital
2024
Shenzhen University
2024
Hunan Agricultural University
2022
Huazhong University of Science and Technology
2014
Jilin University
2012
Shenyang Agricultural University
2012
Background: Fatty liver is a major metabolic disorder that occurs during early lactation in high-producing dairy cows. Sterol regulatory element-binding protein-1c (SREBP-1c) an important transcription factor regulates lipid synthesis by regulating the expression of metabolism genes. Methods: In this study, we reduced SREBP-1c adenovirus-mediated with low vector (AD-GFP-SREBP-1c) to study effects on deposits bovine hepatocytes. The levels and enzyme activities SERBP-1c its target genes were...
Abstract Background Subclinical ketosis (SCK) causes economic losses in the dairy industry because it reduces milk production and reproductive performance of cows. Hypothesis/Objectives To evaluate whether carboxymethyl chitosan‐loaded reduced glutathione (CMC‐rGSH) nanoparticles can alleviate incidence or degree SCK a herd. Animals Holstein cows 21 days postpartum (n = 15). Methods The trial uses prospective study. Five with serum β‐hydroxybutyric acid (BHBA) ≥1.20 mmol/L aspartate...
The objective of this study was to determine the effects NEFA and glucose on carnitine palmitoyltransferase-I (CPT-I) mRNA expression in cultured bovine hepatocytes using real-time reverse transcription polymerase chain reaction ELISA methods. results indicated that CPT-I increased gradually, but translation not significantly changed, with concentrations ranging from 0 3.0 mmol/L (P<0.01). Furthermore were enhanced when 1.2 decreased 4.8 A high concentration found reduce fatty acid...
Endometritis is a disease that affects reproductive health in dairy cows and causes serious economic damage to the industry world-wide. Although recent years, application of mesenchymal stem cell (MSC) therapy for treatment inflammatory diseases has attracted much attention, there are few reports use MSCs cows. In present study, our objective was explore inhibitory effects bovine adipose-derived cells (bAD-MSCs) on lipopolysaccharide (LPS) induced inflammation endometrial epithelial (bEECs)...
Background: Phosphatase and tensin homolog (PTEN) is a potent tumor suppressor gene that also plays vital role in regulating fatty acid metabolism. Here we attempted to elucidate the of PTEN regulation oxidation assembly secretion very low density lipoprotein (VLDL) dairy cow liver. Methods: We transfected primary culture calf hepatocytes with adenovirus-mediated overexpression vector (AD-GFP-PTEN).PTEN-overexpressing control were obtained. Results: Compared controls, significantly...
Inactive ovaries (IOs) affect the estrus cycle and timed artificial insemination (TAI) efficiency in dairy cows during early lactation. The objective of experiment was to determine metabolic changes serum milk whey with IO estrus. Twenty-eight healthy postpartum Holstein similar age, production, body condition were selected at 30 days for tracking 70 postpartum, performance recorded through Afi Farm® software. ovarian status follicular diameter examined by an experienced breeder B-ultrasound...
Inactive ovaries (IO) accounts for 50% of ovarian disease in postpartum dairy cows, which seriously affects their reproductive efficiency. To investigate the metabolic changes serum and follicular fluid cows with IO during lactation, six estrus (E) at 50 to 55 days milk were selected based on B ultrasonic detection clinical manifestations. The differential metabolites between E identified by ultra-high-pressure liquid chromatography-quadrupole time-of-flight mass spectrometry, combined...
Negative energy balance (NEB) is an important risk factor for the dairy cow's anoestrus. The purpose of experiment to screen out differentially expressed proteins (DEPs) in follicular fluid (FF) cows with anoestrus caused by NEB and oestrus from positive (PEB). PEB holstein were selected 14–21 days postpartum according serum concentrations β-hydroxybutyric acid (BHB) glucose (Glu). Based on follicle diameter at 55–60 postpartum, two groups assigned into group (NEB-A; n = 6; < 8 mm) (PEB-E;...
Retained foetal membrane (RFM) is a common reproductive pathology that harms the health of dairy cows. The aim this study was to clarify pathogenesis RFM and screen for an early clinical diagnostic marker disease by using comparative proteomics bioinformatics. Three placental tissues from three cows equal number normal were collected study. There 240 spots showing significant differential expressions known proteins between two types tissue samples. Between maternal samples, there 214 with...
MicroRNAs (miRNAs) can post-transcriptionally regulate gene expression and play an important role in the development function of organs cells cattle. This study identified novel differentially expressed miRNAs maternal placenta Holstein cattle with retained fetal membranes (6 cows for each group). The found 4,596,223 reads that matched bovine genome normal library (5,930,853 total), a total 4,270,190 were present membrane (5,367,946 total). In study, 36 33 libraries. It was discovered 69...
Postpartum inactive ovaries (IOs) in dairy cows reduce the economic returns of industry. It is related to energy metabolism disorder, inflammatory response and oxidative stress. The objective this study was investigate association liver function index (LFI) serum cytokines at 21 days postpartum with IO predict risk cows. blood 60 parturient collected through caudal root vein 3, 21, 28 55 postpartum. Ultrasonography performed 50 determine follicular development. With median LFI as standard,...
Joint interface property is of great importance to the whole machine tool behaviour, especially for mechanical and thermal behaviour. Traditionally, studies joint focus on behaviour or separately, while in fact they couple tightly. By studying contact resistance thermo-mechanical coupled mechanism fixed interface, a model considering effect presented this paper. Compared with experimental data specimens high-speed motorised spindle, accuracy verified modelling method. This would be useful...
Metabolic disorders may lead to the inactive ovaries of dairy cows during early lactation. However, detailed metabolic profile with around 55 days postpartum has not been clearly elucidated. The objective this study was investigate difference in and estrus from perspective serum metabolites. According clinical manifestations, B-ultrasound scan, rectal examination, 15 were assigned group (E; follicular diameter 15–20 mm) ovary (IO; &lt;8 mm increased &lt;2 within 5 over two...
Vitamin E (VE) is an essential fat-soluble nutrient for dairy cows. deficiency leads to immune suppression and oxidative stress increases the susceptibility of cows reproductive disorders in early post-partum period. However, studies on plasma proteomics VE have not been reported so far. Therefore, purpose this study was understand changes blood protein profile with subclinical In study, levels 14 healthy (>4 μg/ml α-tocopherol) 13 VE-deficient (2-3 were analyzed by tandem mass tag (TMT)....
Intracranial medulloepithelioma is a very rare and highly malignant tumor that typically diagnosed in childhood has an inferior prognosis. In the current report, we described case of fetal intracranial was detected during third trimester by prenatal ultrasonography, which displayed homogenous echogenicity with well-circumscribed margins abundant blood flow. On magnetic resonance imaging, it hyperintense on both T1- T2-weighted imaging. The progressive, rapid expansion within 3 weeks. report...