- Acute Ischemic Stroke Management
- Stroke Rehabilitation and Recovery
- Traumatic Brain Injury and Neurovascular Disturbances
- Cerebrovascular and Carotid Artery Diseases
- Botulinum Toxin and Related Neurological Disorders
- Intracerebral and Subarachnoid Hemorrhage Research
- Venous Thromboembolism Diagnosis and Management
- Neurosurgical Procedures and Complications
- Cerebral Palsy and Movement Disorders
- Organ Donation and Transplantation
- Memory, violence, and history
- Ultrasound in Clinical Applications
- Antimicrobial agents and applications
- Cardiac, Anesthesia and Surgical Outcomes
- Biopolymer Synthesis and Applications
- Musculoskeletal pain and rehabilitation
- Hemodynamic Monitoring and Therapy
- Photographic and Visual Arts
- History of Education in Spain
- Fault Detection and Control Systems
- Health and Lifestyle Studies
- Dysphagia Assessment and Management
- Neural Networks and Applications
- Cardiac Arrest and Resuscitation
- Cerebrospinal fluid and hydrocephalus
Universidad de La Frontera
2013-2023
Clínica Alemana
2009-2021
The George Institute for Global Health
2015-2018
Royal Prince Alfred Hospital
2015-2018
Peking University
2015-2018
The University of Sydney
2015-2018
National Cerebral and Cardiovascular Center
2018
George Institute for Global Health
2017-2018
Westmead Hospital
2018
UNSW Sydney
2018
BACKGROUND: Cerebral swelling in relation to cytotoxic edema is a predictor of poor outcome acute ischemic stroke (AIS) and elevated blood pressure (BP) promotes its development. Whether intensive BP-lowering treatment reduces cerebral uncertain. We aimed determine whether BP lowering the severity after thrombolysis for AIS. METHODS: A secondary analysis ENCHANTED (Enhanced Control Hypertension Thrombolysis Stroke Study), partial factorial, international, multicenter, open-label, blinded end...
Background and Purpose— Patients with acute ischemic stroke intracranial arterial obstructions have a poor prognosis high probability of deteriorating at 24 hours. We aimed to evaluate the diagnostic accuracy power motion mode Doppler (PMD-TCD) compared CT angiography as standard in diagnosing patients presenting <24 Methods— Consecutive emergency department underwent high-resolution brain PMD-TCD within 6-hour difference. Results— A total 100 were included. demonstrated 34 occlusions CTA...
Background The uptake of proven stroke treatments varies widely. We aimed to determine the association evidence‐based processes care for acute ischemic ( AIS ) and clinical outcome patients who participated in HEADPOST (Head Positioning Acute Stroke Trial), a multicenter cluster crossover trial lying flat versus sitting up, head positioning stroke. Methods Results Use 8 were considered: reperfusion therapy eligible patients; unit care; antihypertensive, antiplatelet, statin, anticoagulation...
An extensive corpus of literature supports the positive impact constraint-induced movement therapy (CIMT) on neuroplasticity and recovery function. However, its clinical applicability is limited by time intervention individual modality. We propose to assess efficacy modified CIMT protocols through a group intervention. To determine effectiveness therapy, compared with CIMT, in increasing use functionality paretic upper limb. The study was single-blind, randomized parallel trial. Thirty-six...
Standardized registries may provide valuable data to further improve stroke care. Our aim was obtain updated information about characteristics of patients and management across the Ibero-American countries, using a common in-hospital registry (Safe Implementation Treatments in Stroke–Sociedad Iberoamericana de Enfermedades Cerebrovasculares) as basis for quality improvement.Data this study were entered into Safe Stroke from September 2009 December 2013 by 58 centers 14 countries. Data...
Abstract Water‐soluble polyelectrolytes containing ammonium and sulfonic groups, their polymer–Ag(I) complexes, silver nitrate were investigated as bactericidal compounds for Staphylococcus aureus (Collection No. ATCC 28922) Escherichia coli 6538P) according to the National Committee Clinical Laboratory Standards (NCCL) method. All compounds, except Ag(I), showed activity only S. . Ag(I) high both bacteria. No important effect of molecular weight or macromolecular size on maximum...
<i>Background:</i> Transcranial Doppler (TCD) ultrasound can demonstrate dynamic information. We aimed to evaluate whether TCD generates useful additional information in the emergency room after a multimodal stroke imaging protocol and also this modified management of patients with cerebral infarction. <i>Methods:</i> Patients admitted between April 2006 June 2007 ischemic less than 24 h were subjected consisting noncontrast brain CT, computed tomography angiography,...
Validation of transcranial Doppler in the diagnosis brain
Stroke is the most common specific cause of death in Chile since 2008, representing roughly 10% total deaths country.To analyze hospital discharges with a diagnosis stroke period 2001-2010 regional Chilean health service.Analysis discharge databases department statistics and information (DEIS) Ministry Health for years 2001-2010. All subjects aged over 15 discharged during southern region, were included study.In period, 6,548 due to registered. The diagnoses ischemic hemorrhagic stroke,...
Background The diagnosis of brain death (BD) is complex. For this reason, we aimed to evaluate the accuracy power mode transcranial Doppler (PMD-TCD) in diagnosing BD. Patients and methods admitted an intensive care unit between December 2003 January 2012 were included study if they a structural coma, had no craniectomy, evaluated blind by neurologist using PMD-TCD. BD was based on evaluation that took into consideration absence sedative drugs, median blood pressure >60 mmHg, body...
Sonothrombolysis (ST) is an emerging modality for the treatment of stroke.To assess feasibility to perform ST in a Chilean hospital.Patients attended at private clinic with acute ischemic stroke, between September 2002 and May 2013 eligible endovenous thrombolysis, were studied transcranial Doppler (Spencer PMD 100 or 150®). Those adequate sonographic window demonstrated arterial occlusion monitored continuously site worst residual flow following CLOTBUST study protocol.One thousand twenty...
INTRODUCTION: Atypical Teratoid/Rhabdoid Tumor (ATRT), according to the World Health Organization (WHO) Classification of Tumors, is a highly malignant neoplasm (grade IV) Central Nervous System (CNS) that preferentially manifests in children less than three years age. These tumors are mainly composed rhabdoid cells, with addition or not areas demonstrating characteristics primitive neuroectodermal tumor. Less 40 cases were published literature about this neoplasm. OBJECTIVE: In context our...
Introduction: Because of the complex physiopathology spasticity, it is distinguished as one most significant positive clinical signs upper motor neuron syndrome, constituting a feature that has great impact in neurorehabilitation setting. Thus, current study aimed to determine prevalence, onset, evolution, and prediction spasticity after stroke. Materials Methods: A correlational, longitudinal design was used. total 136 patients were evaluated at following times: 10 days (T1), 3 months (T2),...
La Ultrasonografía tiene un rol relevante en la evaluación del paciente grave tanto emergencia médica como frente a de su curso clínico. Debido al desarrollo tecnológico actualidad se cuenta con máquinas transportables, más baratas y fáciles usar que permiten evaluar el lugar donde encuentra. Es así médicos intensivistas servicios urgencia están familiarizados uso Ecocardiografía situaciones específicas sobre las cuales hay importante apoyo literatura. El peri-operatorio es período puede...
Ischaemic stroke (CVA) is one of the leading causes morbidity and mortality at a global national level. We studied 35 patients, determined arteries that presented higher frequency occlusion in acute ischemic identified middle cerebral artery poste- rior artery. consider it necessary specialists can locate anatomically strokes order to apply neuroprotective therapies improve treatment options preventing secondary obstructions.