A5065680149- Acute Ischemic Stroke Management
- Migraine and Headache Studies
- Long-Term Effects of COVID-19
- Periodontal Regeneration and Treatments
- Dental Implant Techniques and Outcomes
- Cardiovascular Function and Risk Factors
- High Altitude and Hypoxia
- Health, Environment, Cognitive Aging
- Stroke Rehabilitation and Recovery
- Cardiovascular Health and Risk Factors
- Parkinson's Disease Mechanisms and Treatments
- Transplantation: Methods and Outcomes
- Dementia and Cognitive Impairment Research
- Cerebrovascular and Carotid Artery Diseases
- Dysphagia Assessment and Management
- Gastrointestinal disorders and treatments
- Trigeminal Neuralgia and Treatments
- Health and Medical Education
- Dental materials and restorations
- Multiple Sclerosis Research Studies
- Parasitic infections in humans and animals
- Cerebrospinal fluid and hydrocephalus
- Cardiac Structural Anomalies and Repair
- COVID-19 and healthcare impacts
- Biosimilars and Bioanalytical Methods
Higher University of San Andrés
2013-2025
Universidad del Desarrollo
2018-2024
Clínica Alemana
2024
Columbia University Irving Medical Center
2020-2022
Institute of Cardiology
2021
University College Hospital, Ibadan
2021
Morgan Stanley Children's Hospital
2020
Columbia University
2020
Hospital Clínico Universitario de Caracas
2015-2018
Central University of Venezuela
2013-2017
Improving stroke services is critical for reducing the global burden. The World Stroke Organization-World Health Organization-Lancet Neurology Commission on conducted a survey of status in low and middle-income countries (LMICs) compared to high-income countries.Using validated Organization comprehensive questionnaire, we collected data along four pillars quadrangle (surveillance, prevention, acute stroke, rehabilitation) 84 across regions economic strata. also non-communicable diseases 194...
Several brain disorders associated with neuroinflammation show sex differences in their incidence, onset, progression and/or outcome. The different regulation of the neuroinflammatory response males and females could underlie these differences. In this study, we have explored whether reactive gliosis after a penetrating cortical injury exhibits Males presented higher density Iba1 immunoreactive cells proximity wound (0-220 μm) than females. This difference was due to number nonreactive...
The disease caused by severe acute respiratory syndrome coronavirus 2, known as 2019, has resulted in a global pandemic. Reports are emerging of new hyperinflammatory related to 2019 children and adolescents. Centers for Disease Control Prevention designated this multisystem inflammatory children. Our objective was develop clinical inpatient protocol the evaluation, management, follow-up patients with syndrome.
The diagnosis of neurocysticercosis (NCC) remains problematic because the heterogeneity its clinical, immunological, and imaging characteristics. Our aim was to develop assess a new set diagnostic criteria for NCC, which might allow accurate detection of, differentiation between, parenchymal extraparenchymal disease.A group Latin American NCC experts developed by consensus NCC. A multicenter, retrospective study then conducted validate it. reference standard active disappearance or reduction...
Abstract INTRODUCTION Latin American Initiative for Lifestyle Intervention to Prevent Cognitive Decline (LatAm‐FINGERS) is the first non‐pharmacological multicenter randomized clinical trial (RCT) prevent cognitive impairment in America (LA). Our aim present study design and discuss strategies used multicultural harmonization. METHODS This 1‐year RCT (working on a extension) investigates feasibility of multi‐domain lifestyle intervention LA efficacy intervention, primarily function. An...
Introduction: Stroke is one of the leading causes death in Latin America, a region with countless gaps to be addressed decrease its burden. In 2018, at first American Ministerial Meeting, stroke physician and healthcare manager representatives from 13 countries signed Declaration Gramado priorities improve region, commitment implement all evidence-based strategies for care. The second meeting March 2020 reviewed achievements 2 years discussed new objectives. This paper will review 2-year...
Effect of apolipoprotein E (APOE) on Alzheimer's disease and related dementias (ADRD) risk is heterogeneous across populations, with scarce data Hispanics/Latinos. APOE genotype was studied in 12,221 Hispanics/Latinos (per cohort via metanalysis): Caribbean-Hispanics, Mexicans, Mexican-Americans, Peruvians/Bolivians. A subsample had longitudinal assessment plasma p-tau. We tested the modifying effects global local ancestries. Results were replicated an independent Peruvian brain samples. ε4...
Objective: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) primarily causes illness. However, neurological sequelae from novel disease 2019 (COVID-19) can occur. Patients with conditions may be at higher risk of developing worsening their underlying problem. Here we document our initial experiences as neurologic consultants a single center quaternary hospital the epicenter COVID-19 pandemic. Methods: This was retrospective case series adult patients diagnosed SARS-CoV-2 who...
Chronic migraine is a condition with significant prevalence all around the world and high socioeconomic impact, its handling has been challenging neurologists. Developments for understanding mechanisms associated conditions, as well that of new therapies, have quick important, fact which motivated Latin American Brazilian Headache Societies to prepare present consensus. The treatment chronic should always be preceded by careful diagnosis review; detection possible worsening factors...
Abstract. Coronary heart disease is a prevalent condition and leading cause of death in developed countries. Most cases are due to the cluster classical risk factors, such as smoking, diabetes, high blood pressure dyslipidaemia. However, few patients develop severe premature arteriosclerosis spite absence common factors. Here, we present clinical, analytical molecular features 36‐years‐old man who died from advanced ischaemic result cerebrotendinous xanthomatosis (CTX), rare characterized by...
Standardized registries may provide valuable data to further improve stroke care. Our aim was obtain updated information about characteristics of patients and management across the Ibero-American countries, using a common in-hospital registry (Safe Implementation Treatments in Stroke–Sociedad Iberoamericana de Enfermedades Cerebrovasculares) as basis for quality improvement.Data this study were entered into Safe Stroke from September 2009 December 2013 by 58 centers 14 countries. Data...
Abstract The energy transition presents a critical juncture for the oil and gas industry. As we navigate toward more sustainable future, digital oilfield (DOF) technologies play pivotal role in optimizing operations, reducing environmental impact, ensuring security. This paper aims to explore best practices lessons learned from two decades of implementations. scope includes analyzing successful case studies, challenges faced, practical guidelines short-term DOF adoption context transition....
Las empresas mineras han vuelto sus ojos sobre América Central, y El Salvador no ha sido la excepción: actualmente en el país se debate creación aprobación de una ley minera cara a regular actividad extractiva. En este contexto desarrolla presente estudio, que recoge opinión aquellas personas son vecinas exploraciones sin duda serían las primeras afectadas caso inicie esta industria. desarrollado través técnica encuesta realizado mes octubre 2007, encontró mayoría consultadas oponen apertura...
To measure dimensional changes of the periimplant soft tissue profile after removal a single implant fixed interim restorations using digital impression procedures.Ten participants presenting with implant-supported (ISFIRs) on maxillary esthetic zone. A 2-step silicone was made arch ISFIRs. The experimental procedure obtained by making impressions gingival contours immediately ISFIR removal. control formed fabricating definitive casts from conventional ISFIRs as customized transfer and these...
Biological drugs and nonbiological complex with expired patents are followed by biosimilars follow-on that supposedly similar comparable the reference product in terms of quality, safety efficacy. Unlike simple molecules can be copied reproduced, heterogeneous need specific regulations from health pharmacovigilance agencies. A panel 14 Latin American experts on multiple sclerosis nine different countries met to discuss recommendations regarding for treating sclerosis. Specific measures...
Introduction Restoring function and esthetics are essential aspects of periodontology restorative dentistry. Depending on their extension the tissues involved, treatment non‐carious cervical lesions (NCCLs) associated with gingival recessions may require a multidisciplinary approach, different periodontal techniques have been described. Case Presentation This case report presents an innovative approach to treat deep NCCL combined recession in canine region female patient. A Computer Aided...
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Abstract Background Non‐carious cervical lesions (NCCLs) refer to the loss of dental hard tissue in region due physical and/or chemical factors, often associated with disappearance cemento‐enamel junction (CEJ), posing challenges both diagnosis and treatment gingival recessions (GR). This case study introduces two protocols for multidisciplinary CEJ reconstruction prior root coverage therapy (RCT). Methods Two patients GR NCCLs were treated using techniques: both, analogically digitally...
Consenso Latino-Americano para as Diretrizes de Tratamento da Migrânea Crônica. Headache Medicine. 2012;3(4):150-61