A5062577034- Photodynamic Therapy Research Studies
- Cancer Mechanisms and Therapy
- Nanoplatforms for cancer theranostics
- Cancer Research and Treatments
- RNA modifications and cancer
- Pancreatic and Hepatic Oncology Research
- Esophageal Cancer Research and Treatment
- Statistical Methods and Inference
- Art Education and Development
- Statistical Methods and Bayesian Inference
- Immunotherapy and Immune Responses
- Cancer, Hypoxia, and Metabolism
- Listeria monocytogenes in Food Safety
- Prostate Cancer Treatment and Research
- Fecal contamination and water quality
- Cancer-related gene regulation
- Diversity and Impact of Dance
- Immune Response and Inflammation
- Theatre and Performance Studies
- Advanced Statistical Methods and Models
- Early Childhood Education and Development
- Nosocomial Infections in ICU
- Cancer-related Molecular Pathways
- T-cell and B-cell Immunology
- PARP inhibition in cancer therapy
Dongduk Women's University
2023-2024
The University of Texas Southwestern Medical Center
2023
Southwestern Medical Center
2023
Mokpo National University
2022
University of Michigan
2018-2019
McGill University Health Centre
2014
National Cancer Institute
2013
National Institutes of Health
2013
McGill University
2012
Johns Hopkins Medicine
2007
Tumor mutational burden and heterogeneity has been suggested to fuel resistance many targeted therapies. The cytosine deaminase APOBEC proteins have implicated in the signatures of more than 70% human cancers. However, mechanism underlying how cancer cells hijack mediated mutagenesis machinery promote tumor heterogeneity, thereby foster therapy remains unclear. We identify SYNCRIP as an endogenous molecular brake which suppresses APOBEC-driven prostate (PCa). Overactivated APOBEC3B,...
Surgery is required for the curative treatment of lung cancer but associated with high rates postoperative pneumonias predominantly caused by gram negative bacteria. Recent evidence suggests that these severe infectious complications may decrease long term survival after hospital discharge via recurrence, mechanism unclear. Lung cells have recently been demonstrated to express Toll‐like receptors (TLR) mediate pathogen recognition. We hypothesized incubation non‐small cell (NSCLC)...
15144 Background: Germ-line SNPs in DNA repair enzymes are studied as predictive factors various cancers. More rarely studied, however, is the presence of tumor cells and how they relate to both germ-line well outcome. We explored relationship between esophageal adenocarcinoma using two systems: (1) Cell lines, determine whether loss heterozygosity (LOH) occurs near genes, for genotyping; (2) Patient samples, differ normal mucosa. Methods: For LOH analysis, we examined three short tandem...
Clostridium difficile assays are unable to differentiate between active infection and asymptomatic carriage. Failure account for noninfectious causes of diarrhea in hospitalized patients may contribute overdiagnosis CDI, leading unnecessary treatment increased cost care. This study assessed if a best practice alert (BPA) could improve ordering practices. A BPA was instituted tertiary academic medical center the electronic system on July 17, 2017 alerting providers C. testing their patient...
Abstract INTRODUCTION: Surgery is required for curative treatment of lung cancer but associated with a high rate bacterial infections such as pneumonia. There emerging clinical evidence to suggest that infectious complications may decrease survival after surgery, the mechanism unclear. Interactions between bacteria and host cells are mediated by specialized pathogen recognition receptors, which Toll-like receptors (TLRs) best characterized. We others have shown express TLRs, their function...
In analyzing data set we usually assume a tentative model that seems to be valid. But the assumed may incorrect in respect of distributional assumption, regression relationship, and so on. The causes larger variance estimates than naive are given as inverse Hessian matrix. this paper, discuss robust more valid presence misspecification. Through Monte Carlo study investigate improvement against attaining nominal coverage probabilities for coefficients generalized linear models. We consider...