Xiang‐Ming Wang

ORCID: 0000-0001-5543-1981
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About
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Research Areas
  • Natural Fiber Reinforced Composites
  • Flame retardant materials and properties
  • Advanced Cellulose Research Studies
  • Lignin and Wood Chemistry
  • biodegradable polymer synthesis and properties
  • Immune Cell Function and Interaction
  • Wood Treatment and Properties
  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Clinical Research Studies
  • Numerical methods in engineering
  • Metal and Thin Film Mechanics
  • Neurological Disease Mechanisms and Treatments
  • Renal Diseases and Glomerulopathies
  • Coronary Interventions and Diagnostics
  • Barrier Structure and Function Studies
  • Science, Research, and Medicine
  • Cytomegalovirus and herpesvirus research
  • Thermochemical Biomass Conversion Processes
  • Nephrotoxicity and Medicinal Plants
  • Tribology and Wear Analysis
  • Lubricants and Their Additives
  • Microplastics and Plastic Pollution
  • Tree Root and Stability Studies
  • Circular RNAs in diseases
  • Antibiotic Resistance in Bacteria

Hebei Medical University
2025

Fourth Hospital of Hebei Medical University
2025

Peking University
2020-2024

Center for Life Sciences
2022-2024

FPInnovations
2010-2024

Tongren Hospital
2021

First Affiliated Hospital of Wannan Medical College
2013

Wannan Medical College
2013

Huaiyin Institute of Technology
2013

Shenyang Aerospace University
2013

In coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome 2 (SARS-CoV-2) infection, the relationship between severity and host immune response is not fully understood. Here we performed single-cell RNA sequencing in peripheral blood samples of 5 healthy donors 13 patients with COVID-19, including moderate, convalescent cases. Through determining transcriptional profiles cells, coupled assembled T cell receptor B sequences, analyzed functional properties cells. Most...

10.1038/s41590-020-0762-x article EN other-oa Nature Immunology 2020-08-12

Characterization of the dynamic change in immunological landscape during malignant transformation from precancerous lesions to cancerous squamous cell carcinoma (SCC) is critical for application immunotherapy. Here, we performed single-cell RNA-Seq (scRNA-Seq) 131,702 cells 13 tissues oral (OSCC), 3 samples leukoplakia, and 8 adjacent normal samples. We found that tumor-infiltrating CD4+ CD8+ T were functionally inhibited by immunosuppressive ligands expressed on various types myeloid or...

10.1172/jci157649 article EN cc-by Journal of Clinical Investigation 2022-08-16

The preparation of bio-composites based on engineering plastic is always restricted by the low thermal stability lignocellulose. In this study, lignocellulose was improved boric acid modification. Then, borated characterized to analyze mechanism involved in improvement stability. Furthermore, untreated and combined with polyamide 6 produce bio-composites. effects content modification color, mechanical properties resulting composites were compared analyzed. Boric protected from degradation,...

10.1016/j.matdes.2020.108589 article EN cc-by-nc-nd Materials & Design 2020-02-24

Abstract Clear cell renal carcinoma (ccRCC) is a heterogeneous disease with features that vary by ethnicity. A systematic characterization of the genomic landscape Chinese ccRCC lacking, and associated tumor thrombus (ccRCC-TT) remain poorly understood. Here, we applied whole-exome sequencing on 110 normal-tumor pairs 42 normal-tumor-thrombus triples, transcriptome 61 tumor-normal 30 primary-thrombus from 152 patients ccRCC. Our analysis reveals mutational signature aristolochic acid (AA)...

10.1038/s41467-020-14601-9 article EN cc-by Nature Communications 2020-02-06

To obtain a comprehensive scenario of T cell profiles and synergistic immune responses, we performed single-cell RNA sequencing (scRNA-seq) on the peripheral cells 14 individuals with chronic human immunodeficiency virus 1 (HIV-1) infection, including nine treatment-naive (TP) eight antiretroviral therapy (ART) participants (of whom three were paired TP cases), compared results four healthy donors (HD). Through analyzing transcriptional CD4+ CD8+ cells, coupled assembled receptor sequences,...

10.1038/s41421-021-00367-x article EN cc-by Cell Discovery 2022-03-28

Abstract Wood–polymer composites (WPCs) were prepared from poplar wood ( P. ussuriensis Komarov) in a two‐step procedure. Maleic anhydride (MAN) was first dissolved acetone and impregnated into wood; this followed by heat process; then, glycidyl methacrylate (GMA) styrene (St) further the MAN‐treated wood, second thermal treatment. Finally, novel WPC fabricated. The reactions occurring WPC, aggregation of resulting polymers, their interaction with substrate analyzed scanning electron...

10.1002/app.32837 article EN Journal of Applied Polymer Science 2010-09-24

This study aimed to evaluate the feasibility and accuracy of non-electrocardiogram (ECG)-triggered chest low-dose computed tomography (LDCT) with a kV-independent reconstruction algorithm in assessing coronary artery calcification (CAC) degree cardiovascular disease risk patients receiving maintenance hemodialysis (MHD). In total, 181 MHD who needed CT calcium score (CACS) scannings sequentially underwent non-ECG-triggered, automated tube voltage selection, high-pitch LDCT ECG-triggered...

10.1186/s12872-025-04499-w article EN cc-by-nc-nd BMC Cardiovascular Disorders 2025-01-24

Clinical use of antimicrobials faces great challenges from the emergence multidrug-resistant pathogens. The overexpression drug efflux pumps is one major contributors to multidrug resistance (MDR). Reversing function a promising approach overcome MDR. In life-threatening fungal pathogen Candida albicans, facilitator superfamily (MFS) transporter Mdr1p can excrete many structurally unrelated antifungals, leading Here we report counterintuitive case reversing MDR in C. albicans by using...

10.1016/j.scib.2020.12.035 article EN cc-by-nc-nd Science Bulletin 2020-12-31

Research on fire retardant–treated wood and wood-based composites has been conducted in China for over two decades. Although many kinds of retardants have studied, the focus is still mainly compounds or mixtures containing phosphorus, nitrogen, boron, which can be used a water solution solid impregnation. Fire-retardant treatment methods panels are either pretreatment veneers, fibers, particles, strands before hot pressing impregnation waterproof with fire-retardant solutions. Though...

10.13073/0015-7473-60.7.668 article EN Forest Products Journal 2010-12-01

Abstract In COVID-19 caused by SARS-CoV-2 infection, the relationship between disease severity and host immune response is not fully understood. Here we performed single-cell RNA sequencing in peripheral blood samples of five healthy donors 13 patients including moderate, severe convalescent cases. Through determining transcriptional profiles cells, coupled with assembled T cell receptor B sequences, analyzed functional properties cells. Most types showed a strong interferon-alpha response,...

10.1101/2020.07.23.217703 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2020-07-24

The curing behavior of lignin-based phenol-formaldehyde (LPF) resin with different contents nano-crystalline cellulose (NCC) was studied by differential scanning calorimetry (DSC) at heating rates (5, 10 and 20&degC/min) the bonding property evaluated wet shear strength wood failure two-ply plywood panels after soaking in water (48 hours room temperature followed 1-hour boiling). test results indicated that NCC content had little influence on peak temperature, activation energy total heat...

10.4236/msa.2015.66060 article EN Materials Sciences and Applications 2015-01-01

Demand for high-performance biocomposites is increasing due to their ease of processing, low environmental impact, and in-service performance. This study investigated the effect boric acid modification wood flour on polycarbonate (PC) composites’ thermal stability, fire retardancy, water absorption, creep behavior. The retardancy increased with content, char residue by 102.3% compared that pure PC. However, absorption resulting composites hydroxyl groups flour. Wood also improved anti-creep...

10.3390/polym13142234 article EN Polymers 2021-07-07

The flame retardancy of wood–polymer composites significantly affects their potential applications. Thus, multilayered wood flour/high-density polyethylene (HDPE)/polycarbonate (PC) were prepared via thermocompression to improve the fire in this paper. Thermal degradation behavior, retardancy, and flexural strengths resulting investigated using a thermogravimetric analysis, cone calorimetry, mechanical testing machine, respectively. Results revealed that boric acid treatment reduced heat...

10.3390/polym14142833 article EN Polymers 2022-07-12

Particles from waste laminated particleboards were recovered using various thermo-hydrolytic treatments. The size distribution and three main chemical properties, such as pH, buffer capacity, nitrogen content of the control resulting particles determined. effects treatment temperature duration on properties recycled investigated. gel time urea-formaldehyde (UF) resin also measured. test results suggested that pH after hot water soaking pre-treatment different treatments increased to extents,...

10.15376/biores.15.2.3774-3786 article EN BioResources 2020-04-03

Titanium-alloy laminates fabricated by sheet materials using diffusion bonding process have drawn more and attention in the recent years. Proper placement of nonwelded zones on (DB) interface within titanium-alloy as crack arrest can improve damage tolerance. To achieve optimal tolerance via designing non-welded zones, it is necessary to study fatigue growth characteristics for this type adjusting all relevant parameters such geometrical sizes, locations, number which highly time consuming....

10.1155/2013/820871 article EN Mathematical Problems in Engineering 2013-01-01

Abstract Organosolv lignins were modified with different fungal species. The used as raw materials for preparing lignin-phenol-formaldehyde (LPF) resins. Oriented strandboard ...

10.13073/fpj-d-14-00034 article EN Forest Products Journal 2014-10-15
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