- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Atrial Fibrillation Management and Outcomes
- Cardiac pacing and defibrillation studies
- Functional Brain Connectivity Studies
- Cardiac Imaging and Diagnostics
- Genetic Associations and Epidemiology
- Schizophrenia research and treatment
- Bipolar Disorder and Treatment
- Ovarian function and disorders
- Medicinal Plant Pharmacodynamics Research
- Heart Rate Variability and Autonomic Control
- Chronic Disease Management Strategies
- Fuel Cells and Related Materials
- BRCA gene mutations in cancer
- Lipid metabolism and disorders
- Computational Drug Discovery Methods
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diabetes Management and Education
- Long-Term Effects of COVID-19
- Coronary Interventions and Diagnostics
- Pancreatic function and diabetes
- Advanced MRI Techniques and Applications
- Pregnancy and Medication Impact
- Endometriosis Research and Treatment
Second Xiangya Hospital of Central South University
2021-2025
Central South University
2021-2025
Guizhou Provincial People's Hospital
2018-2024
Education Department of Fujian Province
2024
Institute of Cardiology
2024
Guangzhou University of Chinese Medicine
2023
Affiliated Hospital of Southwest Medical University
2023
Controversy still exists that whether clopidogrel should add proton pump inhibitors (PPIs) in patients with coronary heart disease after percutaneous intervention (PCI). The aim of this study was to evaluate the efficacy and safety added vs. for treatment We systematically searched PubMed, EMBASE, Web Science, Chinese Biomedical Medical Literature database, Cochrane Library all clinical trials were published on topic through October 2018. specifically selected evaluated PCI. RevMan 5.0...
Abstract Background The complexity of left atrial appendage (LAA) in patients with nonvalvular fibrillation (NVAF) is closely related to LAA thrombosis and stroke incidence. But the classification morphology not uniform controversial. Hypothesis This study divided into two categories according investigate risk structural NVAF patients. Methods A total 336 were enrolled continuously this study. group non‐thrombosis whether thrombus presence LAA. Through computer three‐dimensional...
Background: Discriminating between major depressive disorder (MDD) and bipolar (BD) remains challenging cognitive deficits in MDD BD are generally recognized. In this study, the fractional amplitude of low-frequency fluctuation (fALFF) approach was performed to explore neural activity cognition first-episode, drug-naïve patients, as well relationship altered fALFF values clinical or psychometric variables. Methods: A total 21 25 41 healthy controls (HCs) completed assessments resting-state...
Abstract Background Previous studies have focused on the clinical characteristics of hospitalized patients with novel 2019 coronavirus disease (COVID-19). Limited data are available for convalescent patients. This study aimed to evaluate discharged COVID-19 Methods In this retrospective study, we extracted 134 in Guizhou Provincial Staff Hospital from February 15 March 31, 2020. Cases were analyzed basis demographic, clinical, and laboratory as well radiological features. Results Of...
Abstract Introduction This study aimed to identify the characteristics of unipolar and bipolar electrogram (UniEGM BiEGM) in guiding successful ablation premature ventricular contractions (PVCs) originating from free wall aspect tricuspid annulus (TA). We hypothesized that negative concordance pattern (NCP) on onset UniEGM BiEGM, together with least value difference between earliest BiEGM dV/dTmax, might improve accuracy conventional mapping. Methods Results Thirty consecutive patients who...
To evaluate the trend of change in efficacy and safety catheter ablation compared with antiarrhythmic drug therapy (ADT) for rhythm control patients atrial fibrillation (AF) over time.The online databases PubMed EMBASE were searched relevant studies. STATA software (version 12.0) was used to perform meta-analysis meta-regression.Fifteen randomized controlled trials including 2249 AF identified. The pooled results showed that associated a 52% reduction risk recurrence ADT [risk ratio (RR) =...
Previous researches have demonstrated that abnormal functional connectivity (FC) is associated with the pathophysiology of bipolar disorder (BD). However, inconsistent results were obtained due to different selections regions interest in previous researches. This study aimed at examining voxel-wise brain-wide alterations first-episode, drug-naive patient BD an unbiased way. A total 35 patients and 37 age-, sex-, education-matched healthy controls underwent resting-state magnetic resonance...
Radiofrequency catheter ablation (RFCA) of premature ventricular contractions (PVCs) originating from common locations such as the proximal and middle fascicles His-Purkinje system (HPS) has been established an effective therapy. This report aims to highlight electrophysiological properties RFCA PVCs uncommon HPS.Among 57 patients with fascicular PVCs, 3 sites were retrospectively analyzed.We identified three separately diseased fascicles, dead-end tract (DET), distal fascicle. In contrast...
Objective Cardiac CT (CCT) is an emerging non-invasive modality for assessing left atrial appendage (LAA) thrombus, but the results were conflicting. Our study aims to evaluate accuracy of CCT detecting LAA thrombus in patients undergoing catheter ablation fibrillation, using trans-oesophageal echocardiography (TEE) as reference standard. Design Case-control study. Setting Patient data collected from a tertiary hospital China between 2017 and 2022. Participants The enrolled 726 (male: 60.2%,...
Abstract Background and aims Electrophysiological characteristics radiofrequency catheter ablation (RFCA) of premature ventricular contractions (PVCs) originating from the superior septal left ventricle (SSLV) have not yet been fully characterized. Methods results This study included 247 patients who underwent RFCA for PVCs arising outflow tract between February 2020 August 2022. The successful site was on SSLV in 37 patients. In 12 (32.4%) those patients, a low amplitude high frequency...
Background The precise association between green tea intake and gastrointestinal disorders remains controversial. This study aimed to investigate the potential causal through a two-sample Mendelian randomization (MR) study. Methods Utilizing publicly accessible data from genome-wide studies (GWAS), we identified SNPs strongly linked with variables multiple large databases serve as instrumental (IVs). MR analyses were executed utilizing inverse variance weighting (IVW) method, resultant...
Abstract Early repolarization syndrome is associated with an increased risk of arrhythmic death caused by ventricular fibrillation (VF). VF usually initiated premature contractions (PVCs), and PVCs commonly arise from Purkinje system, the outflow tract, papillary muscles. We report case a patient J wave syndromes recurrent VF, triggered originating tricuspid annular region. was successfully suppressed catheter ablation triggering PVCs, there has been no recurrence during follow‐up period 6 months.
Atrial fibrillation (AF) is the most common arrhythmia disease and associated with several cardiovascular cerebrovascular diseases. Consequently,the mortality rate of AF has increased in recent years. At present, treatment mainly based on medication radiofrequency ablation, but there are limitations such as adverse reactions high recurrence rates. Recently, autonomic nervous regulation become a new for AF. Our previous study showed that acupuncture at Neiguan (PC6) point can treat by...
Default mode network (DMN) plays a key role in the pathophysiology of bipolar disorder (BD). However, homogeneity this BD is still poorly understood. This study aimed to investigate abnormalities NH DMN at rest and correlation between clinical variables patients with BD. Forty drug-naive thirty-seven healthy control subjects participated study. Network (NH) independent component analysis (ICA) methods were used for data analysis. Support vector machines (SVM) method was analyze different...
Abstract The Afirma GSC aids in the clinical decision making for patients with indeterminate thyroid nodule cytology (ITN). 2018 validation study was a prospective, multi-center study, conducted on patient cohort ITN. All underwent surgery without known genomic information and were assigned histopathology diagnosis by an expert panel blinded to all information. results showed sensitivity (SN) of 91%, specificity (SP) 68%, positive predictive value (PPV) 47%, negative (NPV) 96% at cancer...
Abstract Idiopathic ventricular arrhythmias originating from the aortic sinus of Valsalva often show preferential conduction to right‐ventricular outflow tract, which may render radiofrequency ablation more difficult. We describe a patient with symptomatic premature contractions left‐ventricular tract origin presenting variation QRS morphology during ablation. The correlation between characteristics local voltage potentials and real site arrhythmia is discussed.
Background: The origin distribution in right ventricular outflow tract (RVOT) arrhythmias (VAs), as well the initial ablation effectiveness of reversed U-curve method and antegrade method, remains unclear. Objectives: To investigate RVOT-type VAs compare two methods. Method: Consecutive patients who had idiopathic were prospectively enrolled. After activation mapping, randomly assigned to supravalvular strategy using or subvalvular method. primary outcome was (IA) success, defined successful...