A5016188638- Structural Health Monitoring Techniques
- Pharmaceutical Practices and Patient Outcomes
- Vibration and Dynamic Analysis
- Force Microscopy Techniques and Applications
- Advanced MEMS and NEMS Technologies
- Mechanical and Optical Resonators
- Health Systems, Economic Evaluations, Quality of Life
- Probabilistic and Robust Engineering Design
- Burn Injury Management and Outcomes
- Adhesion, Friction, and Surface Interactions
- Architecture, Modernity, and Design
- Wound Healing and Treatments
- Advanced Battery Technologies Research
- Bladed Disk Vibration Dynamics
- Palliative Care and End-of-Life Issues
- Architecture, Design, and Social History
- Ultrasonics and Acoustic Wave Propagation
- Historical Art and Culture Studies
- Asthma and respiratory diseases
- Substance Abuse Treatment and Outcomes
- Composite Structure Analysis and Optimization
- Energy Harvesting in Wireless Networks
- Historical Studies and Socio-cultural Analysis
- Sleep and related disorders
- Mechanical stress and fatigue analysis
University College Cork
2015-2025
University College Dublin
2024
Vanderbilt University
2014-2024
Mater Misericordiae University Hospital
2024
Boys Town National Research Hospital
2023
Technological University Dublin
2023
Cork University Hospital
1995-2023
Cardiff University
2021
National University of Ireland
2020
University of Louisville
2014-2019
Abstract Objective To examine the effect of optimising drug treatment on related hospital admissions in older adults with multimorbidity and polypharmacy admitted to hospital. Design Cluster randomised controlled trial. Setting 110 clusters inpatient wards within university based hospitals four European countries (Switzerland, Netherlands, Belgium, Republic Ireland) defined by attending doctors. Participants 2008 (≥70 years) (≥3 chronic conditions) (≥5 drugs used long term). Intervention...
The main objective of the present study was to test hypothesis that patients with cardiopulmonary disease can reliably identify different sensory qualities their experience breathlessness. A secondary aim examine whether there any relationship between such specific descriptors sensation breathlessness and a patient's clinical diagnosis. randomly ordered list 45 breathing discomfort related exertion administered on two occasions 208 disease; identified applied own experience. total 169 were...
Medicines reviews by general practice pharmacists improve patient outcomes, but little is known about the associated economic particularly in patients at higher risk of medicines-related harm. To conduct an cost-benefit analysis providing person-centred medicines to with hyperpolypharmacy (prescribed ≥ 10 regular medicines) and/or high harm across multiple settings. Service delivery costs were calculated based on pharmacist's salary, recorded timings, and a practitioner fee. Direct cost...
Abstract Aim The aim of this study was to investigate the impact pharmacist‐led person‐centred medicines reviews in general practices on appropriateness, polypharmacy indicators (high‐risk prescribing markers), and patient‐reported outcome measures (PROMs). Methods Four pharmacists conducted ten between January 2021 December 2022 for patients with hyperpolypharmacy (prescribed ≥10 regular medicines) and/or at high risk medicines‐related harm. Prescribing recommendations were provided...
TyrA is a member of the dye-decolorizing peroxidase (DyP) family, new family heme-dependent recently identified in fungi and bacteria. Here, we report crystal structure complex with iron protoporphyrin (IX) at 2.3 A. dimer, each monomer exhibiting two-domain, alpha/beta ferredoxin-like fold. Both domains contribute to heme-binding site. Co-crystallization presence an excess chloride allowed for unambiguous location active site specific residues involved heme binding. The reveals Fe-His-Asp...
Abstract Background The EQ-5D-3L and EQ-5D-5L are two generic health-related quality of life measures, which may be used in clinical health economic research. They measure impairment 5 aspects health: mobility, self-care, usual activities, pain/discomfort anxiety/depression. aim this study was to assess the performance measuring self-reported status older patients with substantial multimorbidity associated polypharmacy. Methods Between 2017 2019, we administered a subset participating OPERAM...
Tests of the electron beam injector for Boeing/Los Alamos Average Power Laser Experiment have demonstrated first time operation a photocathode radio frequency gun accelerator at 25% duty factor, exceeding previous operating parameters by three orders magnitude. The macropulse format was 30 Hz and 8.3 ms with micropulse 27 MHz. currents up to 32 mA been accelerated 5 MeV an average power 160 kW. peak current 128 mA. exceeds cathode performance factor 1000. Emittance measurements demonstrate...