A5030412430- Infective Endocarditis Diagnosis and Management
- Antimicrobial Resistance in Staphylococcus
- Olfactory and Sensory Function Studies
- Cardiac Valve Diseases and Treatments
- COVID-19 Clinical Research Studies
- Streptococcal Infections and Treatments
- HIV Research and Treatment
- HIV-related health complications and treatments
- Advanced Chemical Sensor Technologies
- COVID-19 and healthcare impacts
- Orthopedic Infections and Treatments
- Cytomegalovirus and herpesvirus research
- Long-Term Effects of COVID-19
- Biochemical Analysis and Sensing Techniques
- COVID-19 and Mental Health
- Toxoplasma gondii Research Studies
- Death Anxiety and Social Exclusion
- Hepatitis Viruses Studies and Epidemiology
- Liver Disease Diagnosis and Treatment
- Forensic Toxicology and Drug Analysis
- Bacterial Identification and Susceptibility Testing
- Cardiac Structural Anomalies and Repair
- Antifungal resistance and susceptibility
- Palliative Care and End-of-Life Issues
- Aging and Gerontology Research
Hadassah Medical Center
2010-2024
Hebrew University of Jerusalem
2011-2024
Children's Hospital of Orange County
2024
University Medical Center
2019-2023
University Hospital and Clinics
2023
Association Française pour le Dépistage et la Prévention des Handicaps de l’Enfant
2022
Erasmus University Rotterdam
2022
Erasmus MC
2022
Hospital Quirónsalud Barcelona
2022
Hadassah Academic College
2010-2021
ObjectivesTo characterize longitudinal symptoms of mild coronavirus disease 2019 (COVID-19) patients for a period 6 months, to potentially aid in management.MethodsPhone interviews were conducted with 103 COVID-19 Israel over 6-month (April 2020 October 2020). Patients recruited via social media and word mouth interviewed up 4 times, depending on reports their unresolved symptoms. Inclusion criteria required participants be residents aged 18 years or older, positive real-time PCR results...
To assess quality of informed consent among patients undergoing procedures and patient's preferences about decision-making. Cross-sectional survey hospitalized before surgery or other procedures. Preference for decision-making was elicited in ambulatory patients. Large academic general hospital 10 clinics, over the years 2002–04. Data initial were presented at staff meetings, recommending asking to restate what explained them. Rate recall explanations on risks alternative options; rate...
Morning blood pressure surge (MS) is accepted to increase cardiovascular risk, but it not clear how should be defined. Because dipping on 24-h ambulatory monitoring (ABPM) associates with improved outcome we hypothesized that MS will predict mortality independent of dipping.We investigated a cohort 2,627 patients referred for ABPM available values at least 1-h after awakening, and related them all-cause mortality.During 22,353 person-years follow-up, 246 died. We used Cox proportional...
Invasive Candida infections pose a major public health problem worldwide and is cause of nosocomial bloodstream infection. Our aim was to assess dynamics in incidence, species distribution antifungal susceptibility candidemia episodes Jerusalem, better understand the epidemiology invasive isolates direct therapy. Methods We analyzed incidence dynamics, pattern 899 during 2005-2016 Jerusalem. Results The overall relatively low 0.62 per 1000 admissions. albicans leading pathogen (39.4%);...
Background: Schizophrenia (SCZ) is a debilitating psychiatric disorder with complex and poorly understood etiology. Numerous studies have reported high prevalence of Toxoplasma gondii-specific immunoglobulins in SCZ patients, indicating past infection, but the clinical significance this association remains unclear. Methods: Using electronic health records (EHRs) from national system, we systematically examined impact medication purchases medical conditions on risk. We compared 3,273...
INTRODUCTION: Identifying modifiable Alzheimer's disease (AD) risk factors may clarify etiology and improve prevention. METHODS: We studied 9,124 AD patients (2004-2024) 18,248 matched controls from Leumit Health Services, Israel, screening all medications used over 10 prior years. Odds ratios (OR) for (FDR <5%) were adjusted age, gender, socioeconomic status, comorbidities via logistic regression. Findings validated in TriNetX (117M U.S. patients) with Cox models propensity score-matched...
Background: Cancers of the digestive tract, notably colorectal cancer (CRC) and pancreatic malignancies, represent a major global health burden, with microbial risk factors remaining poorly understood. Atovaquone-proguanil (A-P), an antimalarial agent, has been associated reduced CRC incidence. We hypothesized that A-P may lower cancers by eliminating Toxoplasma gondii, protozoan capable colonizing mucosa. Methods: Using TriNetX US Collaborative Network, we conducted propensity score-matched...
Clinical diagnosis of coronavirus disease 2019 (COVID-19) is essential to the detection and prevention COVID-19. Sudden onset loss taste smell a hallmark COVID-19, optimal ways for including these symptoms in screening patients distinguishing COVID-19 from other acute viral diseases should be established.We performed case-control study who were polymerase chain reaction-tested (112 positive 112 negative participants), recruited during first wave (March 2020-May 2020) pandemic Israel....
ABSTRACT Objectives The multifaceted disease manifestation of COVID-19 requires longitudinal characterization symptoms, to aid with screening and management. Methods Phone interviews follow-ups were completed 112 mild RT-PCR-positive adult patients, over a six weeks period. Results More than one symptom at onset was experienced by ∼70 the patients. Over third patients fever, dry cough, headache, or muscle ache as first symptom. If fatigue reported, it usually appear. Smell taste changes had...
Bariatric surgery is increasingly performed in morbidly obese HIV patients. Limited data exist regarding antiretroviral drug exposure after bariatric surgery. We report a case of patient who underwent sleeve gastrectomy. Abacavir, lamivudine, and dolutegravir therapeutic monitoring was at several time points pre- postsurgery. Significantly increased levels were measured, particularly for abacavir, whose ∼12-fold. Several mechanistic explanations these findings are discussed.
Diabetes mellitus (DM) is more common among people living with human immunodeficiency virus (PLWH) compared healthy individuals. In a prospective multicenter study (N = 248), we identified normoglycemic (48.7%), prediabetic (44.4%), and diabetic (6.9%) PLWH. Glycosylated hemoglobin (HbA1c) fasting blood glucose (FBG) sensitivity in defining dysglycemia was 96.8%, while addition of oral tolerance test led to reclassification only 4 patients. Inclusion 93 additional PLWH known DM enabled...
Covid-19 disease is implicated in increased mortality among immunocompromised patients. The JAK inhibitor, baricitinib (bar), or the IL-6 tocilizumab (toc), demonstrated a survival benefit patients with severe disease.However, evidence supporting their use scarce.We aimed to assess clinical outcomes of bar/toc treatment A multi-center registry consecutive hospitalized due during Omicron variant dominance period. After excluding who did not require high oxygen supply, treated were compared by...
Patients admitted to hospital with influenza B and A in Jerusalem, Israel, during the 2015-2016 2017-2018 seasons demonstrated similar rates of intensive care unit (ICU) admission associated disease severity. Most (63%) ICU patients received B-mismatched trivalent vaccine. These findings call into question equivalence quadrivalent vaccines preventing severe B.
ABSTRACT Background Clinical diagnosis of COVID-19 poses an enormous challenge to early detection and prevention COVID-19, which is crucial importance for pandemic containment. Cases may be hard distinguish clinically from other acute viral diseases, resulting in overwhelming load laboratory screening. Sudden onset taste smell loss emerge as hallmark COVID-19. The optimal ways including these symptoms the screening suspected patients should now established. Methods We performed a...
The objective of this study was to determine morbidity and mortality rates in dogs that had undergone a total hip replacement surgery with implantation either cemented or cementless prosthesis (BioMedtrix LLC, Whippany, NJ). survival time after surgery, the date death cause were collated from an ongoing registry maintained on consecutive procedures by single surgeon. A review 1,864 entered revealed 642 which known. mean life span 11.3 years, longest being 17.1 years. 4.66 16.1 Multiorgan...
Purpose: To describe the rehabilitation treatment and outcome of progressive multifocal leukoencephalopathy (PML) in context Human Immunodeficiency Virus (HIV).Method: The medical history two HIV-positive patients with PML was reviewed; information on their neurological impairments, gathered.Results: patients, a 47-year-old married man 34-year-old single man, both suffered from dense right hemiplegia motor aphasia. Their course delayed prolonged: they were suitable for intensive...
Worldwide use of synthetic cannabinoids (SCs) is rapidly increasing, in part due to the generation numerous new compounds, sidestepping legal restrictions. Their detection using standard toxicology panels difficult, their vast heterogeneity and lack structural resemblance cannabinoids. Sympathetic overactivity arterial spasm play a role some life-threatening reactions SCs, such as coronary or cerebral vasoconstriction. Here we report patient with repeated consumption SCs that led mesenteric...
Abstract Background Synthetic cannabinoids (SC) are chemical substances which activate cannabinoid receptors similarly to tetrahydrocannabinol, but with a higher efficacy. These used as illicit recreational drugs, often smoked herbal mixtures. The continuing availability and rapid evolution of SC is an ongoing health risk. adverse effects wide ranging, span from mild behavioral changes death. Knowledge regarding gastrointestinal (GI) manifestations use sparse. Methods Single tertiary-care...