W. Y. Sun

ORCID: 0000-0001-5807-6874
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About
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Research Areas
  • Particle physics theoretical and experimental studies
  • Quantum Chromodynamics and Particle Interactions
  • High-Energy Particle Collisions Research
  • Computational Physics and Python Applications
  • Cardiac Valve Diseases and Treatments
  • Black Holes and Theoretical Physics
  • Aortic aneurysm repair treatments
  • Aortic Disease and Treatment Approaches
  • Dark Matter and Cosmic Phenomena
  • Influenza Virus Research Studies
  • Congenital Heart Disease Studies
  • Cardiac Arrest and Resuscitation
  • Nuclear physics research studies
  • Head and Neck Cancer Studies
  • Neutrino Physics Research
  • Cardiac tumors and thrombi
  • Infective Endocarditis Diagnosis and Management
  • Immune Response and Inflammation
  • Salivary Gland Tumors Diagnosis and Treatment
  • Transplantation: Methods and Outcomes
  • Particle Detector Development and Performance
  • Ear and Head Tumors
  • Cardiac and Coronary Surgery Techniques
  • Acute Kidney Injury Research
  • Traumatic Brain Injury and Neurovascular Disturbances

Jilin Medical University
2024-2025

Jilin University
2021-2025

Nanjing Normal University
2020-2022

Fudan University Shanghai Cancer Center
2018-2022

Qilu Hospital of Shandong University
2008-2020

Wuhan Institute of Virology
2019-2020

Chinese Academy of Sciences
2019-2020

University of Chinese Academy of Sciences
2019-2020

Shandong University
2007-2019

Shanghai Medical College of Fudan University
2018

Excessive inflammation associated with the uncontrolled release of proinflammatory cytokines is main cause death from influenza virus infection. Previous studies have indicated that inhibition interferon gamma-induced protein 10 (IP-10), interleukin-8 (IL-8), monocyte chemoattractant 1 (MCP-1), or their cognate receptors has beneficial effects. Here, by using monocytic U937 cells capable secreting three important during A infection, we measured inhibitory activities on production six...

10.3389/fimmu.2019.01393 article EN cc-by Frontiers in Immunology 2019-06-21

Objectives Multiple blood products are often required during and after ventricular assist device (VAD) implants. Generally, transfusion therapy is empirically guided by conventional laboratory tests. In this study, we aimed to compare a thromboelastography (TEG)-based algorithm with coagulation test-based respect product utilization in patients undergoing VAD implant. Methods From June 2010 May 2012, total of 39 consecutive underwent implantation. Patients implant were retrospectively...

10.1111/jocs.12302 article EN Journal of Cardiac Surgery 2014-02-11

Internal mammary arteries graft failure in coronary artery bypass grafting (CABG) is mostly considered to be a result of competitive flow (CF) from the native artery, which significantly limits future revascularization options.With left internal (LIMA) anastomosed anterior descending (LAD) using an off-pump technique, CABG was performed on 15 Chinese swine. Then we produced varying degrees stenosis proximal LAD with adjustable occluder, measured mean LIMA and detected plasma concentrations...

10.1093/ejcts/ezs507 article EN European Journal of Cardio-Thoracic Surgery 2012-09-22

Cardiovascular disease (CVD) is a class of diseases that involve the heart or blood vessels. It reported body mass index (BMI) risk factor for CVD. Genome-wide association studies (GWAS) have recently provided rapid insights into genetics CVD and its factors. However, specific mechanisms how BMI influences are largely unknown. We think may by shared genetic pathways. In order to confirm this view, we conducted pathway analysis GWAS, which examined approximately 329,091 single nucleotide...

10.1038/srep13025 article EN cc-by Scientific Reports 2015-08-12

Influenza virus infections can lead to viral pneumonia and acute respiratory distress syndrome in severe cases, causing significant morbidity mortality posing a great threat human health. Because of the diversity influenza strains drug resistance current direct antiviral agents, there have been no effective drugs as yet cure all patients infected by viruses. Natural products from plants contain compounds with diverse structures that potential interact multiple host factors. In this study, we...

10.3390/v12050557 article EN cc-by Viruses 2020-05-18

Abstract Background While the most suitable approach for treating persistent/recurrent papillary thyroid carcinoma (PTC) remains controversial, reoperation may be considered an effective method. The efficacy of in patients with locoregional PTC, especially those unsatisfactory radioactive iodine (RAI) ablation results, is still uncertain. This study aimed to clarify clinical management strategies PTC and explore factors that affect long-term patient outcomes after reoperation. Methods In...

10.1186/s12893-022-01819-1 article EN cc-by BMC Surgery 2022-11-02

The pro-survival transcription factor myocyte enhancer 2D (MEF2D) is identified to exhibit pro-tumor effects based on clinical and experimental studies. However, the detailed mechanisms underlying IGF-1-MEF2D pathway-induced tumor biology in cardiac myxoma (CM) was not clear. Here, we investigated role of MEF2D CM tissues cells using RT-PCR, western blot, gene silencing, et al. Our findings revealed significantly increased compared with adjacent normal closely related size. In vitro assay...

10.1007/s13277-015-4386-y article EN Tumor Biology 2015-11-12

Abstract Background Sun’s procedure is currently recognized as the standard for acute type A aortic dissection (AAAD). But operation istoo difficult beginners. We hope to reduce difficulty and complications of this operation. Methods The arch was immediately cross-clamped after stented graft inserted into distal aorta. Thereafter, lower-body perfusion restored. Then, anastomosis performed between proximal stent 4-branched Dacron graft. other arteries were anastomosed arched branch Results...

10.1186/s13019-020-01370-1 article EN cc-by Journal of Cardiothoracic Surgery 2020-11-12

Initial state radiation (ISR) plays an important role in $e^+$$e^-$ collision experiments such as the BESIII. To correct ISR effects measurements of hadronic cross-sections $e^+e^-$ annihilation, iterative method that weights simulated events is proposed here to assess efficiency event selection and correction factor for observed cross-section. The were generated only once, obtained cross-sectional line shape was used iteratively weigh same evaluate corrections until results converge....

10.48550/arxiv.2011.07889 preprint EN other-oa arXiv (Cornell University) 2020-01-01

Objective To investigate the experiences in treatment of congenital coronary artery fistula(CAF). Methods The clinical data 21 patients with CAF who were admitted to Qilu Hospital Shandong University from December 2005 April 2014 retrospectively analyzed. There 12 males, 9 females, their age ranged 2 months 74 years old, a mean 27.8 years. All performed echocardiography confirm fistula, or diagnosed by angiography. Thirteen underwent surgical repair cardiopulmonary bypass (CPB), 3...

10.3760/cma.j.issn.2095-7041.2016.03.008 article EN Chin J Anat Clin 2016-06-06

Objective: Aortic arch replacement in acute type A aortic dissection patients remains a most challenging cardiovascular operation. This article aims to show our Modified Y-Graft Technique using the Femoral Artery Bypass (FAB) and One Minute Systemic Circulatory Arrest (OSCA) assess short-term outcomes of patients.Methods: Between February 2015 November 2017, 51 with underwent replacement. Among them, 23 patients' procedure used FAB 28 utilized both OSCA. The intraoperative data postoperative...

10.2139/ssrn.3468365 article EN SSRN Electronic Journal 2019-01-01

Aortic arch replacement in acute type A aortic dissection patients remains the most challenging cardiovascular operation. Herein, we described our modified Y-graft technique using Femoral Artery Bypass (FAB) and One Minute Systemic Circulatory Arrest (OSCA) technique, assessed short-term outcomes of patients.Between February 2015 November 2017, 51 with underwent replacement. Among them, 23 FAB while 28 both OSCA. The intraoperative data postoperative follow-up were recorded. traditional...

10.1186/s13019-020-01156-5 article EN cc-by Journal of Cardiothoracic Surgery 2020-05-20
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