Brent A. Chang

ORCID: 0000-0001-5821-4640
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About
Contact & Profiles
Research Areas
  • Head and Neck Cancer Studies
  • Reconstructive Surgery and Microvascular Techniques
  • Salivary Gland Tumors Diagnosis and Treatment
  • Tracheal and airway disorders
  • Voice and Speech Disorders
  • Head and Neck Surgical Oncology
  • Ear and Head Tumors
  • Head and Neck Anomalies
  • Reconstructive Facial Surgery Techniques
  • Tumors and Oncological Cases
  • Thyroid and Parathyroid Surgery
  • Airway Management and Intubation Techniques
  • Trauma Management and Diagnosis
  • Nasal Surgery and Airway Studies
  • Sinusitis and nasal conditions
  • Oral and Maxillofacial Pathology
  • Cancer Diagnosis and Treatment
  • Cancer and Skin Lesions
  • Otolaryngology and Infectious Diseases
  • Cleft Lip and Palate Research
  • Infectious Diseases and Mycology
  • Nonmelanoma Skin Cancer Studies
  • Oropharyngeal Anatomy and Pathologies
  • Cardiac, Anesthesia and Surgical Outcomes
  • Radiomics and Machine Learning in Medical Imaging

Mayo Clinic Hospital
2018-2025

Mayo Clinic in Florida
2022-2024

WinnMed
2022-2024

Mayo Clinic in Arizona
2023-2024

Louisiana State University Health Sciences Center Shreveport
2019-2022

Louisiana State University
2021

Louisiana State University in Shreveport
2020

Overton Brooks VA Medical Center
2020

University of British Columbia
2009-2018

Vancouver General Hospital
2017

We present an interesting case of a 74‐year‐old female who presented with spinal accessory neuropathy following ipsilateral right‐sided carotid endarterectomy 6 months after the initial injury. Subsequent surgical exploration revealed clip that had been placed directly across nerve. Clip removal and neurolysis was subsequently performed, leaving nerve intact. After intervention, she immediately demonstrated increased bilateral shoulder shrug motion continues to improve her function physical...

10.1002/lary.32012 article EN The Laryngoscope 2025-01-27

Abstract Background Velopharyngeal insufficiency (VPI) is a known complication of transoral surgery (TOS) for oropharyngeal HPV‐mediated squamous cell carcinoma. Controversy exists regarding adequate resection margins balancing functional and oncologic outcomes. Methods This retrospective study was exempted by the IRB. Patients who underwent TOS from January 2017 to October 2022 were included. Patient characteristics, treatment details, outcomes evaluated. Results Fifty‐five patients Mean...

10.1002/hed.27741 article EN Head & Neck 2024-03-20

To describe and evaluate a four step systematic approach to dissecting the recurrent laryngeal nerve (RLN) starting at cricothyroid junction during thyroid surgery (subsequently referred as retrograde medial approach).All thyroidectomies completed by senior author between August 2014 January 2016 were retrospectively reviewed. Patients excluded if concurrent lateral or central neck dissection was performed. A follow up period of 1 year included.Surgical photographs illustrations demonstrate...

10.1186/s40463-018-0306-7 article EN cc-by-nc Journal of Otolaryngology - Head and Neck Surgery 2018-09-17

Importance Postoperative radiation therapy for close surgical margins in low- to intermediate-grade salivary carcinomas lacks multi-institutional supportive evidence. Objective To evaluate the oncologic outcomes and with positive margins. Design, Setting, Participants The American Head Neck Society Salivary Gland Section conducted a retrospective cohort study from 2010 2019 at 41 centers. Margins were classified as R0 (negative), R1 (microscopically positive), or R2 (macroscopically...

10.1001/jamaoto.2023.3952 article EN JAMA Otolaryngology–Head & Neck Surgery 2023-12-14

To detect microsatellite abnormalities in the primary tumours and plasma of patients with breast carcinoma.Plasma was obtained from 17 carcinoma before surgery. Corresponding tumour benign lymph node (control) samples for each were paraffin blocks. DNA extracted embedded tissue using previously described methods.The showed two examples loss heterozygosity three instability; one, respectively. Many longer microsatellites (over 200 base pairs) difficult to amplify plasma. The investigations...

10.1136/jcp.52.5.363 article EN Journal of Clinical Pathology 1999-05-01

10.1016/s0967-2109(96)00045-2 article EN Cardiovascular Surgery 1996-12-01

Ectopic parathyroid adenomas can occur in numerous anatomic locations. While ectopic rarely the pharyngeal region, this has not previously been described soft palate.We report first case of adenoma within palate. A 59 year old woman presented with hyperparathyroidism. She remained persistently hyperparathyroid after initial parathyroidectomy. Repeat exploration for a lesion suspicious on PET-CT an parapharyngeal region was unsuccessful treating An palate eventually discovered. Removal...

10.1186/s40463-016-0165-z article EN cc-by-nc Journal of Otolaryngology - Head and Neck Surgery 2016-01-01

AIMS: To attempt to detect p53 gene mutations in the plasma of patients with large bowel carcinoma. METHODS: Plasma was collected from 20 control no history cancer and 17 Corresponding tumour benign lymph node (control) samples for each carcinoma were obtained paraffin blocks. A Dukes9 stage determined tumour. DNA extracted embedded tissue using previously described methods. nested primer polymerase chain reaction protocol used amplification exons 5 8 gene. "Cold" single strand...

10.1136/jcp.51.8.611 article EN Journal of Clinical Pathology 1998-08-01

To review fine needle aspiration (FNA) cytology from sites other than the breast a year before and after introduction of near patient FNA diagnosis (NPFD) service in which were performed by pathologist reported within few minutes.The setting was large hospital rural New Zealand. The NPFD examined retrospectively, prospectively. pattern use quality results starting compared.Time taken to report specimens decreased days minutes. There statistically significant changes following: an increase...

10.1136/jcp.51.7.541 article EN Journal of Clinical Pathology 1998-07-01
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