A5024856899- Liver Disease Diagnosis and Treatment
- Hepatitis C virus research
- Hepatitis B Virus Studies
- Liver Disease and Transplantation
- Gastric Cancer Management and Outcomes
- Pharmacological Effects of Natural Compounds
- Ferroptosis and cancer prognosis
- Folate and B Vitamins Research
- Hepatocellular Carcinoma Treatment and Prognosis
- Liver physiology and pathology
- DNA Repair Mechanisms
- Pancreatic and Hepatic Oncology Research
- Cell death mechanisms and regulation
- Helicobacter pylori-related gastroenterology studies
- Cancer-related molecular mechanisms research
- Epilepsy research and treatment
- Telomeres, Telomerase, and Senescence
- Colorectal Cancer Screening and Detection
- Immune Cell Function and Interaction
- Organ Transplantation Techniques and Outcomes
- Esophageal Cancer Research and Treatment
- Liver Diseases and Immunity
Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine
2017-2025
Beijing University of Chinese Medicine
2018-2024
Estée Lauder (United States)
2006
The interplay between immune cells and metabolic associated fatty liver disease (MAFLD) is a critical research frontier, bridging immunology hepatology. bibliometric findings can guide future funding priorities in the field by highlighting key areas of focus potential therapeutic targets. To analyze literature on MAFLD, identifying trends hotspots. A systematic search Web Science Core Collection from January 1, 2004 to May 20, 2024, yielded 1936 articles MAFLD. Excluding non-research...
Natural killer (NK) cells are a type of innate immune cell that recognize and eliminate tumor infected cells, without prior sensitization or activation. Herein, we aimed to construct predictive model based on NK cell-related genes for hepatocellular carcinoma (HCC) patients assess the feasibility utilizing this prognosis prediction.
Normal human dermal fibroblasts have a limited life-span in vitro and stop proliferation after fixed number of cell divisions. This process by which cells is called senescence. Senescence also characterized decrease the total number. In this study, we an increase death normal as function increasing passage. With passage, showed dead increased DNA fragmentation determined flow cytometry. Serial passage resulted mitochondrial dysfunction, represented loss membrane potential. The apoptotic...
Background and aims Patients with chronic hepatitis B (CHB) in the immune tolerant (IT) phase were previously thought to have no or slight inflammation fibrosis liver. In fact, some CHB patients normal ALT levels still experience liver fibrosis. This study aimed develop validate a non-invasive model for identifying pseudo-immune tolerance (pseudo-IT) of by predicting significant Methods multi-center enrolled total 445 IT-phase who had undergone biopsy training cohort ( n = 289) validation...
Abstract Number connection test A (NCT-A) and digit symbol (DST), the preferential neuropsychological tests to detect minimal hepatic encephalopathy (MHE) in China, haven’t been standardized Chinese population. We aimed establish norms based on a multi-center cross-sectional study MHE cirrhotic patients. NCT-A DST were administered 648 healthy controls 1665 The regression-based procedure was applied develop demographically adjusted for controls. Age, gender, education, age by education...
Abstract Background Nucleos(t)ide analogues (NAs) are the first-line option against chronic hepatitis B (CHB). NAs produce potent suppression of viral replication with a small chance HBsAg seroclearance and high risk virological relapse after discontinuation. The combined therapy plus traditional Chinese medicine (TCM) is widely accepted has been recognized as prospective alternative approach in China. Based on preliminary works, this study was designed to observe therapeutic effect TCM...
Background: Minimal hepatic encephalopathy (MHE) is a subclinical state of with the possibility developing into overt (OHE) and having adverse outcomes. However, no preventative medicine for MHE has been recommended so far. The aim to evaluate therapeutic effect JianPi HuaZhuo XingNao formula (JPHZXN) on MHE, specifically whether JPHZXN decreases OHE occurrence, through randomized controlled trial. Method: Seventy-two patients are enrolled allocated in 1:1 ratio an experimental group control...
The European Association for the Study of Liver Diseases issued "Clinical Practice Guidelines Management Hepatic Encephalopathy" in 2022, which included recommendations clinical diagnosis, assessment, treatment, management, and prevention. Society's "Hepatic Encephalopathy Clinical Chronic Disease," was last published 2014, "Guidelines Diagnosis Treatment Cirrhosis," Chinese Society Hepatology, Medical Association, released 2018, have certain differences updates terms comparison to...
Abstract Background: Nucleos(t)ide analogs (NAs) are the first-line options against chronic hepatitis B (CHB). NAs produce a potent suppression of viral replication but associated with tiny opportunity HBsAg seroclearance and high risks virological relapse after discontinuation. The combined therapy plus traditional Chinese medicine (TCM) is widely accepted has been recognized as prospective alternative approach in China. Based on preliminary works, this study designed to observe therapeutic...
Abstract Background Nucleos(t)ide analogues (NAs) are the first-line option against chronic hepatitis B (CHB). NAs produce potent suppression of viral replication with a small chance HBsAg seroclearance and high risk virological relapse after discontinuation. The combined therapy plus traditional Chinese medicine (TCM) is widely accepted has been recognized as prospective alternative approach in China. Based on preliminary works, this study was designed to observe therapeutic effect TCM...