A5007295795- Health Systems, Economic Evaluations, Quality of Life
- Economic and Financial Impacts of Cancer
- Prostate Cancer Diagnosis and Treatment
- Global Cancer Incidence and Screening
- Prostate Cancer Treatment and Research
- Global Health Care Issues
- Organ Transplantation Techniques and Outcomes
- Healthcare Policy and Management
- Liver Disease and Transplantation
- Reproductive tract infections research
- Organ Donation and Transplantation
- Inflammatory Bowel Disease
- Cystic Fibrosis Research Advances
- Health Services Management and Policy
- Maternal Mental Health During Pregnancy and Postpartum
- Genetic factors in colorectal cancer
- Healthcare cost, quality, practices
- Healthcare Systems and Practices
- Child and Adolescent Psychosocial and Emotional Development
- Patient Satisfaction in Healthcare
- Urinary Tract Infections Management
- Statistical Methods in Clinical Trials
- Multiple and Secondary Primary Cancers
- Iron Metabolism and Disorders
- Healthcare Systems and Challenges
University of Oxford
2014-2019
Ollscoil na Gaillimhe – University of Galway
2012-2018
Aquarius Population Health
2017-2018
National Cancer Institute
2009
Prostate cancer (PCa) is the most common in men UK. Patients with intermediate-risk, clinically localised disease are offered radical treatments such as surgery or radiotherapy, which can result severe side effects. A number of alternative partial ablation (PA) technologies that may reduce treatment burden available; however comparative effectiveness these techniques has never been evaluated a randomised controlled trial (RCT).To assess feasibility RCT PA using high-intensity focused...
The association between low family income and socio-emotional behaviour problems in early childhood has been well-documented, maternal psychological distress is highlighted as central mediating this relationship. However, whether relationship holds for older children, the precise mechanisms by which may influence child unclear. This study investigated at 11 years of age, examined role over time using UK Millennium Cohort Study. primary outcome was parent-reported behavioural problems,...
Introduction: Understanding the extent of patient morbidity is important for managing care: end-stage liver disease (ESLD) terminal stage necessitating transplantation, and which there are 11 clinical classifications with varying impacts on patient’s symptoms severity. Evaluating health-related quality life (HRQoL)2 groups provides insights into how specific health issues affect well-being. Given heterogeneity across sub-group classifications, patient-reported HRQoL measures may exhibit high...
Objectives To quantify the costs, benefits and cost-effectiveness of three multipathogen point-of-care (POC) testing strategies for detecting common sexually transmitted infections (STIs) compared with standard laboratory testing. Design Modelling study. Setting Genitourinary medicine (GUM) services in England. Population A hypothetical cohort 965 988 people, representing annual number attending GUM symptomatic lower genitourinary tract infection. Interventions The decision tree model...
Objectives: The objectives of this paper are to analyse the determinants prostate cancer screening uptake in Republic Ireland and compare role non-need factors among those outside age range recommended as cost-effective for according European Randomised Study Screening Prostate Cancer (ERSPC). Methods: investigation combined a logistic regression analysis uptake, with an estimation income-related concentration indices decomposition using data collected part Survey Lifestyle Nutrition (SLAN)...
Purpose As cancer control strategies have become more successful, issues around survival increasingly important to researchers and policy makers. The aim of this study was examine the role a range clinical socio-demographic variables in explaining variations after prostate diagnosis, paying particular attention healthcare provider(s) i.e. private versus public status. Methods Data were extracted from National Cancer Registry Ireland, for patients diagnosed with 1998–2009 (N = 26,183). A...
To undertake an economic analysis assessing the cost-effectiveness of a single dose oral dexamethasone compared with placebo for relief sore throat.
Prostate cancer (PCa), the most commonly diagnosed among men in United States and Europe, is an escalating resource allocation issue across healthcare systems Western world. The impact of skeletal-related events, associated with castration-resistant prostate (CRPC), considerable many new therapies being sought to treat these events a cost-effective manner.The aim this paper provide insight into level constraints devising cost frameworks for economic analysis CRPC Irish setting.An informal...
Purpose To assess feasibility and health economic benefits costs as part of a pilot study for nurse-led, psychoeducational intervention (NPLI) prostate cancer in order to understand the potential cost effectiveness well contribute design larger scale trial. Methods Men with stable post-treatment were recruited from two centres UK. Eighty-three men randomised NLPI plus usual care or alone (UCA) (42 41 UCA); was delivered primary-care setting (the intervention) included an initial face-to-face...
Purpose With one of the highest incidences across Europe and rest World in 2012, Republic Ireland (RoI) has experienced significant increases prostate cancer (PCa) since 1994. The main driver is widespread use PSA testing which used to detect PCa. This expected have implications on resource RoI. focus this paper was (i) derive costs for PCa pathway, from diagnosis treatment, (ii) estimate overall healthcare expenditure Methods incidence (ICD-10 code: C61), treatment mortality data during...
Purpose With one of the highest incidences across Europe and rest World in 2012, Republic Ireland (RoI) has experienced significant increases prostate cancer (PCa) since 1994. The main driver is widespread use PSA testing which used to detect PCa. This expected have implications on resource RoI. focus this paper was (i) derive costs for PCa pathway, from diagnosis treatment, (ii) estimate overall healthcare expenditure Methods incidence (ICD-10 code: C61), treatment mortality data during...
6618 Background: Over the past decade, U.S. National Cancer Institute (NCI) support for incorporating Patient-Reported Outcomes (PROs) into disease treatment clinical trials has grown considerably, both in number of trials, as well types research questions being addressed and measures used to answer questions. This presentation will compare breadth NCI supported Phase III breast, colo-rectal, lung, prostate cancers that include PRO secondary endpoints activated during two time periods:...
<h3>Introduction</h3> In sexual health services, availability of rapid and accurate point-of-care tests (POCTs) may enable major improvements in care pathway efficiencies outcomes. Previous economic evaluations nucleic acid amplification test (NAAT) POCTs for <i>Chlamydia trachomatis</i> (CT) <i>Neisseria gonorrhoeae</i> (NG) indicate they provide a cost-effective strategy screening genitourinary medicine (GUM) attendees. We estimated costs, benefits cost-effectiveness three strategies using...