A5103132047- Dental materials and restorations
- Dental Implant Techniques and Outcomes
- Temporomandibular Joint Disorders
- Endodontics and Root Canal Treatments
- Lung Cancer Diagnosis and Treatment
- Orthodontics and Dentofacial Orthopedics
- Cardiac Imaging and Diagnostics
- Lung Cancer Treatments and Mutations
- dental development and anomalies
- Laser Applications in Dentistry and Medicine
- Cerebrovascular and Carotid Artery Diseases
- Tracheal and airway disorders
- Dental Erosion and Treatment
- Cardiovascular and exercise physiology
- Dental Trauma and Treatments
- Drug Transport and Resistance Mechanisms
- Cardiovascular Disease and Adiposity
- Medical Imaging and Pathology Studies
- Radiomics and Machine Learning in Medical Imaging
- Advanced MRI Techniques and Applications
- Dental Research and COVID-19
- Oral and Maxillofacial Pathology
- Advanced X-ray and CT Imaging
- High-pressure geophysics and materials
- Cardiac Health and Mental Health
National Cerebral and Cardiovascular Center
2017-2024
Tokyo Medical and Dental University
2013-2023
Hirosaki University
2003-2023
The University of Tokyo
2023
Hirosaki University Hospital
2001-2023
Tohoku University
2008-2022
Japan Cancer Society
2018-2022
Kitakyushu Municipal Medical Center
2018-2019
Iwate Medical University
2003-2019
Aichi Institute of Technology
2019
In addition to routine medications topical indomethacin was applied one group of 112 eyes and an appropriate placebo another 106 that underwent intracapsular cataract extraction.The investigation conducted in a prospective double blind fashion over long period time order demonstrate the effects preventing development cystoid macular oedema.Indomethacin drops were instilled once day before surgery, twice on 3 times daily for 2 weeks postoperatively.The prevalence oedema as detected by...
This study was conducted to enhance the tensile bond strengths of resin cements zirconia ceramics. Fifty-six ceramic specimens (Cercon Base) and twenty-eight silica-based (GN-1, GN-1 Ceramic Block) were air-abraded using alumina. Thereafter, divided into two subgroups 28 each according surface pretreatment; no pretreatment (Zr); internal coating technique (INT). For INT, coated by fusing ceramics Ceram Kiss). surfaces conditioned with/without a silane coupling agent followed bonding with one...
Recently, metal-free restoration has become the standard in prosthetic treatment. However, it is still unclear which combination most effective preventing root fracture and secondary caries. The purpose of this study was to evaluate influence different post systems, crown materials, thickness luting agents on stress distribution around margins, cervical dentin tip post. Ninety-six mandibular first premolar models were developed analyzed using finite element analysis (FEA). Two designs...
summary The regional tensile bond strengths of two dual‐cure composite resin core materials to root canal dentine using either a one or two‐step self‐etching adhesive were evaluated. Extracted premolar teeth decoronated and their canals prepared depth 8 mm width 1·4 mm. In group, one‐step (Unifil Self‐etching Bond) was applied the walls post‐space light‐cured for 10 s. After which, post‐spaces filled with Core) then half specimens 60 s other placed in darkness 30 min. second primer (ED...
The aim of the present study was to evaluate fracture load and mode thin Ceria-stabilized tetragonal zirconia polycrystals/Al2O3 nanocomposites (Ce-TZP/A) Yttria-stabilized polycrystals (Y-TZP) crown frameworks. Artificial maxillary second premolars were prepared for metal-ceramic all-ceramic restorations Co-Cr tooth analogs duplicated. 10 standard (0.5 mm overall thickness) zirconia-ceramic frameworks (Y-TZPs) preparation modified (a 0.3-mm-thick framework increased in thickness by adding a...
The purpose of this study was to investigate clinical outcomes following stereotactic body radiotherapy (SBRT) for lung metastases as oligo-recurrence. From May 2003 June 2014, records 66 patients with 76 oligo-recurrences in the lungs treated SBRT were retrospectively reviewed. Oligo-recurrence primary sites and patient numbers follows: lungs, 31; colorectal, 13; head neck, 10; esophagus, 3; uterus, others, 6. median dose 50 Gy (range, 45–60 Gy) administered a 5 5–9) fractions. All received...
Abstract Aims To investigate the clinical impact of T1 mapping for detecting myocardial impairment in takotsubo cardiomyopathy (TTC) over time. Methods and results In 23 patients with apical ballooning type TTC, following 3T magnetic resonance (MR) examinations were performed at baseline 3 months after TTC onset: T2-weighted imaging, T2 mapping, native extracellular volume fraction (ECV), late gadolinium enhancement. Eight healthy controls underwent same MR examinations. Serial...
Scope Polymethoxylated flavones (PMFs) are a group of natural compounds known to display wide array beneficial effects promote physiological fitness. Recent studies reveal circadian clocks as an important cellular mechanism mediating preventive efficacy the major PMF Nobiletin against metabolic disorders. Sudachitin is enriched in Citrus sudachi , and its functions action poorly understood. Methods results Using reporter cells, it shows that modulates amplitude period Bmal1 promoter‐driven...
Objective: The purpose of the present study was to investigate reaction periodontal ligament excessive occlusal loading by observing histological changes and osteopontin induction. possibility ligand for receptor activator nuclear factor κB (RANKL) participation in induction also discussed. Background: precise mechanism breakdown remains unclear. We established an experimental model vivo . Osteopontin is known be produced upon mechanical considered induce migration osteoclasts resorption...
The case history is presented of a 61 year old man with von Recklinghausen's disease who developed spontaneous haemothorax. In spite being asymptomatic for five days after drainage, he died as result fatal sudden re-bleeding. post mortem examination showed dissection and rupture the left subclavian artery. Microscopically, disarrangement smooth muscle decrease elastic fibre was observed in ruptured Haemothorax patients may require thoracotomy, even if condition patient appears to be stable.
Background:Acute decompensated heart failure (ADHF) is generally considered to be a problem of fluid volume overload, therefore accurately quantifying the degree accumulation critical importance in assessing whether adequate decongestion has been achieved. The aim this study was develop and validate method quantify patients with ADHF.Methods Results:Using multi-frequency bioelectrical impedance analysis (BIA), we measured extracellular water (ECW) 130 ADHF on admission at discharge. We also...
In 2008, the Guidelines for diagnosis and treatment of patients with vasospastic angina (coronary spastic angina) [[1]JCS Joint Working Group (JCS 2008): digest version.Circ J. 2010; 74: 1745-1762Crossref PubMed Scopus (231) Google Scholar] were developed by Japanese Circulation Society, revised version was published in 2013 [[2]JCS 2013): 2014; 78: 2779-2801Crossref Scholar]. Since then, new findings from various fields such as coronary microvascular dysfunction (CMD), biomarkers, imaging,...
The purpose of this study was to determine whether oxygenation in localized working muscle depended on the activity and lactic acidosis level. Seven healthy male subjects underwent five 6-min cycling exercises with work rates 50 watts (25.0 +/- 5.0% VO2max), 100 (36.6 6.2% 150 (50.6 7.7% 200 (67.8 + 6.9% 250 (82.9 7.5% VO2max) while gas exchange parameters blood lactate concentration (BL) were measured. We also measured oxygenated hemoglobin myoglobin (oxy-Hb/Mb) continuous-wave near...
This study evaluated the influence of alveolar bone level on fracture resistance root restored with post and core. Forty-eight extracted human mandibular premolars were divided into six groups. Cast posts cores cemented (MN8 MP8) or resin built up fiber composite (FN8, FP8, FN4, FP4) . Post length was 8 mm (MN8, MP8, FN8, FP8) 4 (FN4 Specimens embedded 2 FN8 FN4) 5 (MP8, FP8 below cement-enamel junction. All specimens loaded at 45 degrees to long axis until fracture. With normal model, cast...
No comprehensive patient-centered and clinical evaluations of the functional effect treatment with implant-supported single crowns (ISSC) have been reported previously.To investigate whether how ISSC affects masticatory function Oral Health-Related Quality Life (OHRQoL) in subjects tooth agenesis.In nine females males (32 + or - 10 years) agenesis treated one to four (68% premolar region), were assessed. The evaluation was performed first after implant placement shortly before crown...
Inositol 1,4,5-triphosphate–mediated calcium (IP3-Ca2+) signal cascade is an essential process in sweet, bitter, and umami taste transduction. Although the main components of this have been identified, candidate regulators them tissues are still unclear. In effort to identify genes involved transduction, we found that a gene encoding lymphoid-restricted membrane protein (Lrmp/Jaw1) was expressed mouse tissues. Here report Lrmp/Jaw1 specifically receptor–expressing cells circumvallate,...
The purpose of this study was to investigate the relationship between tumor size and blood volume for patients with lung tumors, using dual-energy computed tomography (DECT) a gemstone spectral imaging (GSI) viewer. During period from March 2011 2013, 50 57 medically inoperable tumors underwent DECT before stereotactic body radiotherapy (SBRT) 50–60 Gy in 5–6 fractions. taken pretreatment evaluation. region-of-interest given spatial placement set, averages CT value, water density iodine were...
Incidental 18F-fluorodeoxyglucose (18F-FDG) uptake in the prostate is often experienced clinical practice; however, it difficult to determine whether incidental indicative of a malignancy or benign state based on maximum standardized value (SUVmax). In present study, we investigated significance by 18F-FDG positron emission tomography (PET)/CT, and examined differences between malignant from clinicopathological viewpoint. We reviewed 3,236 male subjects who underwent PET/CT scans at Hirosaki...
Coronary high-intensity plaques (HIPs) with a high plaque-to-myocardial signal intensity ratio (PMR) on non-contrast T1-weighted imaging in patients stable coronary artery disease (CAD) are associated future events. To characterize the morphological substrate of HIP, we performed correlative optical coherence tomography (OCT) study.We examined 137 lesions 105 angina pectoris or silent myocardial ischaemia scheduled for percutaneous intervention (PCI) using 3 T magnetic resonance scanner....