A5064404941- Autoimmune and Inflammatory Disorders
- Autoimmune Bullous Skin Diseases
- Mast cells and histamine
- Inflammasome and immune disorders
- Food Quality and Safety Studies
- Cytokine Signaling Pathways and Interactions
- Traditional Chinese Medicine Studies
- Colorectal Cancer Treatments and Studies
- Colorectal and Anal Carcinomas
- Gout, Hyperuricemia, Uric Acid
- Allergic Rhinitis and Sensitization
- Immune cells in cancer
- Psoriasis: Treatment and Pathogenesis
- Traditional Chinese Medicine Analysis
- Plant-based Medicinal Research
- Epigenetics and DNA Methylation
- Dyeing and Modifying Textile Fibers
- Infectious Diseases and Mycology
- IL-33, ST2, and ILC Pathways
- Ferroptosis and cancer prognosis
- Skin Diseases and Diabetes
- Immune Response and Inflammation
- Cancer-related molecular mechanisms research
- RNA Interference and Gene Delivery
- Urticaria and Related Conditions
Baotou Medical College
2009-2024
Inner Mongolia University of Science and Technology
2020-2023
Harbin Medical University
2022
Third Affiliated Hospital of Harbin Medical University
2022
Chinese Academy of Medical Sciences & Peking Union Medical College
2022
CAE (Canada)
2003
Luteolin is a flavonoid found in many fruits, vegetables, and herbs. The antiinflammatory effects of luteolin have been reported. In this study, the effect on allergic diseases underlying molecular mechanism were investigated. We that inhibits Fc epsilon RΙ (FcεRΙ)- Mas-related G protein-coupled receptor X2 (MRGPRX2)-mediated mast cells (MCs) activation, including degranulation release cytokines vitro. Moreover, reduces degree swelling Evans blue exudation mice paw dose-dependent manner....
The imbalanced allocation of medical resources leads to the occurrence cross-regional healthcare-seeking in China. Due low cure rate, advanced colorectal cancer (CRC) patients may seek healthcare for high-level facilities. Investigating status and its associated factors among CRC is important policymakers understand access health services improve quality oncology services.From March 2020 2021, a cross‑sectional, nation-wide, hospital-based, multi-center survey was conducted. Nineteen...
Importance China carries a heavy burden of postherpetic neuralgia, with an unmet need for novel drugs greater efficacy and less prominent neurotoxic effects than existing calcium channel ligands. Objective To investigate the safety crisugabalin, oral α2δ-1 subunit ligand, neuralgia. Design, Setting, Participants This randomized clinical trial, carried out between November 9, 2021, January 5, 2023, at 48 tertiary care centers across had 2 parts. Part 1 was phase 3, multicenter, randomized,...
To explore the utilization, barriers, and factors associated with targeted treatment of Chinese metastatic colorectal cancer (mCRC) patients.
As a highly pathogenic avian influenza virus, A (H5N1) has been reported to infect humans, posing major threat both poultry industry and public health. It is an urgent need develop kind of effective vaccine prevent death reduce the incidence rate H5N1 influenza. Compared with traditional inactivated or attenuated vaccines, deoxyribonucleic (DNA) vaccines have advantages continuously expressing plasmid-encoded antigens inducing humoral cellular immunity. However, immune effect DNA limited its...
Biomarkers are a key tool in early detection, prognostication, survival, and predicting treatment response of colorectal cancer (CRC). However, little is known about biomarker testing for CRC patients real-life clinical practice China. This study aimed to address the usage analyze factors related its acceptance among Chinese with advanced CRC.
microRNAs ale recently discovered,small,non-coding,single-strand RNAs,which can regulate gene expression posttranscriptionally.They are abnormally expressed in many diseases and act as the totalswitchof disease development.Psoriatic lesions have an abnormal microRNA profile when compared with normal skin other chronic inflammatory diseases,such atopic eczema.To investigate role of specific psoriasis may benefit elucidation pathogenesis well development target therapy psoriasis. Key words:...
摘要： 【摘要】 目的 比较浅部、深部感染来源的氟康唑耐药白念珠菌体外对8种抗真菌药物的敏感性及耐药基因突变。方法 26株深部感染来源白念珠菌耐药株、33株浅部感染来源白念珠菌耐药株，参照CLSI酵母菌检测方案M27-A4测定上述菌株对氟康唑、伏立康唑、伊曲康唑、泊沙康唑、两性霉素B、氟胞嘧啶、特比萘芬、米卡芬净8种药物单独或联合的体外敏感性。提取所有耐药菌株DNA，通过PCR检测ERG3、ERG11、FUR1 3种耐药基因的突变情况。满足正态分布和方差齐性检验的定量资料两组间比较采用独立样本t检验，不满足者组间比较采用Mann-Whitney U检验，定性资料组间比较采用卡方检验。结果 氟康唑、伊曲康唑、伏立康唑、泊沙康唑、氟胞嘧啶的最小抑菌浓度（MIC）在浅部感染组和深部感染组间差异均有统计学意义（均P＜0.05），而两性霉素B、米卡芬净的MIC两组间差异无统计学意义（均P > 0.05）。96.6%的菌株特比萘芬MIC值＞64 μg/ml，无法进行组间对比。15株白念珠菌（7株深部感染来源、8株浅部感染来源）特比萘芬 +...