- Oral and Maxillofacial Pathology
- Salivary Gland Tumors Diagnosis and Treatment
- Reconstructive Surgery and Microvascular Techniques
- Ear and Head Tumors
- Reconstructive Facial Surgery Techniques
- Bone Tumor Diagnosis and Treatments
- Facial Nerve Paralysis Treatment and Research
- Head and Neck Cancer Studies
- Cancer Diagnosis and Treatment
- Head and Neck Anomalies
- Soft tissue tumor case studies
- Periodontal Regeneration and Treatments
- Nanoplatforms for cancer theranostics
- Vascular Malformations Diagnosis and Treatment
- Peptidase Inhibition and Analysis
- Vascular Malformations and Hemangiomas
- Cancer-related gene regulation
- Craniofacial Disorders and Treatments
- Wnt/β-catenin signaling in development and cancer
- Meningioma and schwannoma management
- Tumors and Oncological Cases
- Cleft Lip and Palate Research
- Organ and Tissue Transplantation Research
- Facial Trauma and Fracture Management
- Image and Object Detection Techniques
Shanghai Ninth People's Hospital
2014-2024
Shanghai Jiao Tong University
2013-2024
Stomatology Hospital
2023-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2023-2024
University of California, Los Angeles
2024
Yunnan Normal University
2024
AVIC Optronics (China)
2023
National Clinical Research Center for Digestive Diseases
2019-2022
National Clinical Research
2020
Tangshan Gongren Hospital
2015
Abstract Cancer stem–like cells (CSC) thought to contribute head and neck squamous carcinomas (HNSCC) may offer attractive therapeutic targets if a tractable approach can be developed. In this study, we report that silencing c-Met is sufficient suppress sphere formation, tumor initiation, metastatic properties of HN-CSC. Pharmacologic inhibition with the selective inhibitor PF-2341066 preferentially targeted CSC synergized conventional chemotherapy improve efficacy in mouse xenograft model...
J Oral Pathol Med (2013) 42 : 140–147 Background: The carcinogenesis mechanism of adenoid cystic carcinoma (ACC) the salivary gland is poorly understood. MicroRNA155 (miRNA155) has been involved in many malignant tumors. present study aims to examine role miRNA155 tumor growth and invasion ACC. Methods: MiRNA155 expression was determined ACC specimens along with normal glands by quantitative PCR. Using ACC‐2 cells as a model for ACC, cell proliferation examined MTT assay after knocking down...
Abstract Oral squamous cell carcinoma (OSCC) is a prevalent malignancy of the head and neck region associated with high recurrence rates poor prognosis under current diagnostic treatment methods. The development nanomaterials that can improve accuracy therapeutic efficacy great importance for OSCC. In this study, redox‐activatable nanoarchitectonics designed via construction dual‐valence cobalt oxide (DV‐CO) nanospheres, which serve as contrast agent magnetic resonance (MR) imaging, exhibit...
Abstract Multiple intraglandular sialolithiasis for stones deep in the glandular parenchyma may require submandibulectomies, especially if sialendoscopic facilities are unavailable. We describe a gland-sparing intraoral sialolithotomy approach both hilar and intraparenchymal multiple sialoliths. Nine patients with obstructive sialadenitis resulting from sialoliths region submandibular gland were selected this study. Ultrasonography computer tomography (CT) scans performed to determine...
Stafne bone cavity (SBC) is a rare mandibular defect, and the diagnosis management may be confused with unusual contents location. This report for first time presented case of SBC lymph node content. Meanwhile, anterior fatty tissue content reported. Typical SBCs salivary glands are asymptomatic showed well-shaped, ovoid, radiolucent image in posterior mandible below inferior alveolar canal panoramic radiograph. The underwent surgical operation, definite confirmed by histopathological...
Abstract Heat transfer in solids has traditionally been described by Fourier's law, which assumes local equilibrium and a diffusive transport regime. However, advancements nanotechnology the development of novel materials have revealed non-classical heat phenomena that extend beyond this traditional framework. These phenomena, can be broadly categorized into those governed kinetic theory extending it, include ballistic transport, phonon hydrodynamics, coherent Anderson localization,...
In this study, we evaluated the effects of marsupialization in treating unicystic ameloblastoma (UA) and investigated relationship between TP53 interleukin 1 α (IL-1α) expression clinical outcome UA treated with marsupialization. Consecutive patients curettage at Shanghai Ninth People's Hospital were included. According to unified standard, 48 included study. Of these, 20 showed a good response, 10 partial 18 no based on procedure. The proteins IL-1α was detected immunohistochemistry (IHC)....
Unicystic ameloblastomas are a variant of ameloblastoma with definite recurrence rate because the biological behaviours tumour. The risk factors associated disease were analysed in this retrospective study.
The poor SNR of fMRI data requires that many repetitive trials be performed during an event-related experiment to obtain statistically significant levels inferred brain activity. This is costly in terms scanner time, necessitates subjects perform the behavioural task(s) for long durations which may induce fatigue, and vastly increases amount generated. In this paper, we present a method enhance statistical effect size using ICA, so same level significance can obtained with shorter scanning...
Our previous phase 3 trial (NCT01542931) failed to demonstrate improved survival when docetaxel, cisplatin and 5‑fluorouracil (TPF) induction chemotherapy was introduced prior surgery postoperative radiotherapy in patients with locally advanced oral squamous cell carcinoma (OSCC). The aim of the present study investigate long‑term predictive value GDF15 expression for potential personalized treatment strategies OSCC. A total 256 stage III/IVA OSCC from our were enrolled study....