A5086250539- Congenital heart defects research
- Reproductive Health and Contraception
- Long-Term Effects of COVID-19
- Advanced Neuroimaging Techniques and Applications
- Menopause: Health Impacts and Treatments
- Neuroendocrine regulation and behavior
- Endometriosis Research and Treatment
- Functional Brain Connectivity Studies
- Tryptophan and brain disorders
- Stress Responses and Cortisol
- Olfactory and Sensory Function Studies
- Posttraumatic Stress Disorder Research
- Sexual function and dysfunction studies
- Schizophrenia research and treatment
- Pharmacological Effects and Toxicity Studies
- Hypothalamic control of reproductive hormones
- Biotin and Related Studies
- Ovarian function and disorders
- Pregnancy-related medical research
- Neurobiology of Language and Bilingualism
- Williams Syndrome Research
- Vagus Nerve Stimulation Research
- Coronary Artery Anomalies
- Behavioral Health and Interventions
- Advanced Chemical Sensor Technologies
Jena University Hospital
2020-2025
University of Minnesota
2025
University of California, Santa Barbara
2025
Brigham and Women's Hospital
2020-2024
Harvard University
2020-2024
Friedrich Schiller University Jena
2020-2024
German Centre for Cardiovascular Research
2024
University of Minnesota System
2024
Memorial Hospital of Rhode Island
1985
Brown University
1985
Neuropsychiatric symptoms are the most common sequelae of long-COVID. As accumulating evidence suggests an impact survived SARS-CoV-2-infection on brain physiology, it is necessary to further investigate structural changes in relation course and neuropsychiatric symptom burden To this end, present study investigated 3T-MRI scans from long-COVID patients suffering (n = 30), healthy controls 20). Whole-brain comparison gray matter volume (GMV) was conducted by voxel-based morphometry....
The choroid plexus (ChP) is part of the blood-cerebrospinal fluid barrier, regulating brain homeostasis and brain's response to peripheral events. Its upregulation enlargement are considered essential in psychosis. However, timing ChP has not been established. This study introduces a novel magnetic resonance imaging-based segmentation method examine volumes two cohorts individuals with first sample consists 41 early course psychosis (mean duration illness = 1.78 years) 30 healthy...
The COVID-19 pandemic has led to the introduction of unprecedented safety measures, one them being physical distancing recommendations. Here, we assessed whether long-term effects on two important aspects, namely interpersonal distance preferences and touch behaviors. We analyzed nearly 14,000 individual cases from large, cross-cultural surveys – first conducted 2 years prior second during a relatively stable period decreased infection rate in May-June 2021. Preferred distances increased by...
Abstract Irregular menstrual cycles, affecting approximately 30% of women in their reproductive years, are often overlooked research, limiting our insights into the broader spectrum hormonal interactions. Understanding relationship between endogenous hormone fluctuations and brain function across cycle, particularly beyond regular is essential for comprehending mental disorders prevalent women. To this aim, a healthy female with an irregular cycle underwent dense sampling 5 consecutive...
Objectives: We assessed the relationship between emotional awareness (e.g., ability to identify and differentiate our own feelings of others) regional brain volumes in healthy schizophrenia groups. Methods: Magnetic resonance images 29 subjects with 33 matched controls were acquired. Brain gray matter was parcellated using FreeSurfer 28 regions interest associated analyzed. All participants Levels Emotional Awareness Scale (LEAS) Self Other. LEAS scores correlated volume for each hemisphere...
Introduction Seven million people in Germany suffer from depression. The data emphasizes the need for finding a therapeutic alternative individuals who do not respond to standard options. As salience network is key component pathology of disease and also closely related olfactory system, it serves as potential target. Hence, we wanted investigate whether activity structures brain can be influenced by electrical stimulation mucosa nose.
Background Intimate partner violence (IPV) perpetration is highly prevalent among veterans. Suggested risk factors of IPV include combat exposure, post-traumatic stress disorder (PTSD), depression, alcohol use, and mild traumatic brain injury (mTBI). While the underlying pathophysiological characteristics associated with remain largely unknown, previous studies have linked aggression to alterations limbic system. Here, we investigate whether microstructural abnormalities in military Further,...
Abstract Adolescence is a critical period in human development, marked by rapid changes brain structure and function, influenced, part, sex steroids. During adolescence, females may initiate the use of hormonal contraception, which suppresses ovarian production estradiol progesterone. Here, we examined impact contraceptive on adolescent structures using magnetic resonance imaging data from 1,234 individuals ABCD Study (average age = 14 years). We investigated differences cortical thickness,...
Abstract Background The menstrual cycle is a critical indicator of women's reproductive, physical, and mental health, influenced by neuromodulatory sex steroid hormones, including estrogens like 17β-estradiol, estrone. Irregular cycles can lead to various health conditions. Understanding the relationship between endogenous hormone fluctuations brain function across essential for comprehending disorders prevalent in women. Here, we investigated impact hormonal variations on hippocampal...
Abstract Gonadal hormone fluctuations in females have been associated with symptoms of mental health, yet the underlying brain mechanisms remain understudied. Recent advances neuroscience shifted paradigm towards longitudinal tracking, enabling detection subtle changes overlooked conventional cross-sectional analyses. This dense-sampling approach acknowledges rhythmic nature gonadal production. Our study employed three densely sampled who underwent imaging and venipuncture (5 to 7 days per...
Abstract Background Schizophrenia (SCZ) is a severe and chronic brain disorder that affects about 1% of the world population. It among most burdensome illnesses with serious impact on patients, their families society. To this day, lot remains unknown neuropathological cause etiology SCZ. The prominent two-hit theory postulates early neurodevelopmental abnormalities interact later “second hit” which occurs around symptom onset. Recent research points towards role inflammation in...
Abstract Background Cognitive decline is considered a fundamental component in schizophrenia. Abnormalities fronto-striatal-thalamic (FST) sub-circuits are present schizophrenia and associated with cognitive impairments. However, it remains unknown whether abnormalities FST before psychosis onset. This may be elucidated by investigating young adults 22q11.2 deletion syndrome (22q11DS), of whom 30% will develop adulthood. In 22q11DS, decline, most pronounced Verbal IQ (VIQ), precedes the...