A5025886213- Healthcare Systems and Reforms
- Health disparities and outcomes
- Healthcare Policy and Management
- Medical Research and Treatments
- Global Health Care Issues
- Immune Response and Inflammation
- Biomedical Ethics and Regulation
- Vietnamese History and Culture Studies
- Adrenal and Paraganglionic Tumors
- Respiratory Support and Mechanisms
- Cancer, Hypoxia, and Metabolism
- Innovations in Medical Education
- Cardiovascular Health and Risk Factors
- Chinese history and philosophy
- Global Maternal and Child Health
- interferon and immune responses
- Neonatal Respiratory Health Research
- Migration, Aging, and Tourism Studies
- Thyroid Disorders and Treatments
- Aldose Reductase and Taurine
- Neonatal Health and Biochemistry
- Intergenerational Family Dynamics and Caregiving
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Biological and pharmacological studies of plants
- Chronic Obstructive Pulmonary Disease (COPD) Research
Liaoning Shihua University
2024
Peking University
2012-2024
Peking University Sixth Hospital
2019-2024
Nanjing Normal University
2022-2023
University of Chinese Academy of Sciences
2021-2023
Immune Regulation (United Kingdom)
2022
Zunyi Medical University
2019-2022
First People's Hospital of Chongqing
2019-2022
Jinzhou Medical University
2016
Shandong University
2014
Abstract Background The inactivated Sinopharm/BBIBP COVID‐19 vaccine has been widely used in the world and joined COVAX supply program for developing countries. It is also well adapted usage low‐ middle‐income nations due to their low storage requirements. Objective This study aims report on kinetics, durability, neutralizing ability of induced immunity BBIBP vaccine, intensified antibody response elicited by booster. Methods A total 353 healthy adult participants, aged 20–74 years, were...
<b><i>Background:</i></b> The objective of this study was to evaluate the diagnostic value serological markers Krebs von den Lungen-6 (KL-6), surfactant protein-A (SP-A), SP-D, chemokine ligand 2 (CCL2), and 13 (CXCL13) in idiopathic interstitial pneumonia (IIP). <b><i>Methods:</i></b> Patients with IIP aged 18–80 years from First Affiliated Hospital Guangzhou Medical University were enrolled retrospective case-control study. Data on general...
Background: Cognitive impairment is a severe health problem faced by older adults and their families, as well the countries in which they live. Differences place of residence may contribute to differences cognitive function adults, mediating effect social participation has rarely been studied China. Methods: A total 10,014 adult participants were included, using data from Chinese Longitudinal Healthy Longevity Survey (CLHLS). Place was described either city, town, or rural area. The...
Abstract Objective Sleep disturbances are great challenges to older adults’ health promotion. The study tested gender differences in the association between different dimensions of social capital and self-reported sleep duration Chinese rural adults. Design data adults were extracted from a national cross-sectional survey Longitudinal Healthy Longevity Survey (CLHLS) analyzed this study. Setting CLHLS covered 23 provinces China. Participants 6552 respondents aged ≥65 years old involved. Main...
Dendrobium orchids have multiple photosynthetic pathways, which can be used as a model system for studying the evolution of crassulacean acid metabolism (CAM). In this study, based on results net rates (Pn), we classified species into three then employed and compared their chloroplast genomes. The genomes typical quartile structures, ranging from 150,841-153,038 bp. apparent differences in GC content, sequence variability, IR junctions SSC/IRB (JSBs) were measured within among different...
China has entered an aging society since 1999. By the end of 2017, number persons aged ≥60 years had increased to 240.90 million. At present, average life expectancy China's population is 76.4 years, and healthy around 68.7 which means that elderly will be accompanied by disease for about 8 years. The main health problems in include prevalence chronic diseases, disability, insufficient attention older persons' mental area specific differences level elderly. status cannot ignored....
The aim of the present study was to investigate regulatory mechanism nuclear factor (NF)-κB on polymorphonuclear neutrophil (PMN) accumulation and inflammatory response in lung tissues with acute respiratory distress syndrome (ARDS), as well therapeutic effect pyrrolidine dithiocarbamate (PDTC). Mouse models ARDS were established by intraperitoneal injection lipopolysaccharide (LPS). BALB/c mice divided into control, LPS PDTC + groups. expression PMN adhesion molecules, CD11b/CD18...
Introduction: Health, as a fundamental human right, and its fairness equality have gradually been reiterated emphasized around the world. The inequality in health workforce distribution is common China many other developing countries. However, it unknown whether economic conditions insufficient supply of village physicians rural areas worsens inequality. This study article aimed to explore discuss China. Methods: Inequality well trends physician-to-population ratios from 2009 2016 were...
The role of heparin-binding protein (HBP) as an acute inflammatory marker in exacerbations interstitial lung disease (AE-ILD) and some stable ILD patients is not well-established. significance increasing HBP during AE-ILD examined the first attempt to incorporate into evaluation system made. Then, benefit was investigated. (n = 108) were divided subgroups based on phase severity disease. Linear trends across observed, correlations with common markers examined. Further, detection adopted...
Dendrobium officinale, an important orchid plant with great horticultural and medicinal values, frequently suffers from abiotic or biotic stresses in the wild, which may influence its well-growth. Heat shock proteins (Hsps) play essential roles stress response of plants. However, they have not been systematically investigated D. officinale. Here, we identified 37 Hsp20 genes (DenHsp20s), 43 Hsp70 (DenHsp70s) 4 Hsp90 (DenHsp90s) officinale genome. These were classified into 8, 2 subfamilies...
Because chloroplast (cp) genome has more conserved structures than nuclear and mitochondrial genome, it is a useful tool in estimating the phylogenetic relationships of plants. With series researches for cp genomes, there have been comprehensive understandings about features. The genus Bulbophyllum widely distributed Asia, South America, Australia other places. Therefore, an excellent type studying effects geographic isolation.In this study, genomes nine orchids were newly sequenced...
<abstract abstract-type="Summary"> <sec> <b>What is already known about this topic?</b> With the assistance of internet, big data, cloud computing, and other technologies, concept smart elderly care has emerged. </sec><sec> added by report?</b> This study presents information on countries or regions that have conducted research care, as well identifies global hotspots development trends in field. are implications for public health practice?</b> The results suggest future should focus fall...
The saline infusion test (SIT) is a common confirmatory for primary aldosteronism (PA). According to the guideline, postinfusion plasma aldosterone concentration (PAC) of 5-10 ng/dL considered indeterminate, and recommendations diagnostic strategies are currently limited in this situation.To explore whether an addition captopril challenge (CCT) could improve accuracy patients with indeterminate SIT.A total 280 hypertensive high risk PA completed study. Subjects were defined as SIT based on...
Background and Objective: Severe chronic obstructive pulmonary disease (COPD) is the terminal stage of characterized by declined lung function, malnutrition, poor prognosis. Such patients cannot tolerate long-time sports rehabilitation owing to dyspnea fail achieve desired therapeutic effect; therefore, increasing nutritional support will be an important strategy for them. The present study applied metabolomics technology evaluate correlation between serum concentrations polyunsaturated...
Abstract With the global prevalence of COVID‐19 and constant emergence viral variants, boosters for vaccines to enhance antibody titers in human bodies will become an inevitable trend. However, there is a lack data on levels protective effects booster injections. This study monitored analyzed potency responses induced by injection subjects who received three vaccine doses. The was conducted multicenter collaboration recruited 360 healthy adults aged 20–74. Participants first, second, doses...
Being a rare malignancy, adrenocortical carcinoma (ACC) exhibits aggressiveness and poor prognosis. Fibronectin type III domain-containing protein 5 (FNDC5) is transmembrane involved in multiple types of cancer. Aldo-keto reductase family 1 member B10 (AKR1B10) has suppressive role ACC. The present study aimed to investigate the FNDC5 ACC cells as well its mechanisms related AKR1B10. Gene Expression Profiling Interactive Analysis database predicted expression tumour tissue patients suffering...
Abstract Background Under the global aging trend, health issues of elderly have received more and attention. Among them, older adults’ obesity is one common problems elderly. The association between social capital in adults has been analysed discussed previous studies but remains controversial. There are few on China. We examined whether was associated with Chinese adults. Methods data from Longitudinal Healthy Longevity Survey (CLHLS) —wave 8 (2017–2018) used this study. Totally, 10,164...
In the present study, regulatory effect of cytokine-induced neutrophil chemoattractant (CINC) and epithelial neutrophil-activating peptide 78 (ENA-78) on pulmonary (PMN) accumulation in lipopolysaccharide (LPS)-induced acute respiratory distress syndrome (ARDS) mice, therapeutic pyrrolidine dithiocarbamate (PDTC), was investigated. BALB/c mice were divided into control, LPS PDTC + groups using a random number table. The phosphorylation nuclear factor‑κB (NF‑κB) detected western blot, mRNA...