- Autism Spectrum Disorder Research
- Neuroscience and Neuropharmacology Research
- Genetics and Neurodevelopmental Disorders
- Sleep and related disorders
- Sleep and Wakefulness Research
- Virology and Viral Diseases
- Ion channel regulation and function
- Neural dynamics and brain function
- Child Development and Digital Technology
- Microtubule and mitosis dynamics
- Protein Tyrosine Phosphatases
- Ocular Diseases and Behçet’s Syndrome
- Obstructive Sleep Apnea Research
- Retinal Diseases and Treatments
- Assistive Technology in Communication and Mobility
- MicroRNA in disease regulation
- Antibiotics Pharmacokinetics and Efficacy
- Obsessive-Compulsive Spectrum Disorders
- Retinal and Optic Conditions
- Family and Disability Support Research
- Protein Kinase Regulation and GTPase Signaling
- Traditional Chinese Medicine Studies
- Cancer-related molecular mechanisms research
- Pain Mechanisms and Treatments
- Traditional Chinese Medicine Analysis
Guangdong Peizheng College
2023-2024
Key Laboratory of Guangdong Province
2024
South China Normal University
2013-2023
Zhejiang University
2015-2022
Changzhou No.2 People's Hospital
2022
Nanjing Medical University
2022
Hangzhou Normal University
2022
Sir Run Run Shaw Hospital
2020
Chengdu University of Traditional Chinese Medicine
2020
Shanghai East Hospital
2016
The purpose of this study was to observe and compare the clinical efficacy active acupuncture placebo in treatment insomnia mood disorders. 96 patients with Chengdu were randomly divided into two groups (1:1). group (AA n = 48) received tube Park sham device deep needle insertion. (PA a retractable shaft blunt tip. same points cycles used both groups. overall score for Pittsburgh Sleep Quality Index (PSQI) is primary outcome. Secondary outcomes recorded sleep rate, self-reported depression...
Neuroligins (NLs), a family of postsynaptic cell-adhesion molecules, have been associated with autism spectrum disorder. We reported that dysfunction the medial prefrontal cortex (mPFC) leads to social deficits in an NL3 R451C knockin (KI) mouse model autism. However, underlying molecular mechanism remains unclear. Here, we find N-methyl-D-aspartate receptor (NMDAR) function and parvalbumin-positive (PV+) interneuron number expression are reduced mPFC KI mice. Selective knockdown NMDAR...
It is widely recognized that robot-based interventions for autism spectrum disorders (ASD) hold promise, but the question remains as to whether social humanoid robots could facilitate joint attention performance in children with ASD. In this study, responsive was measured under two conditions which different agents, a human and robot, initiated via video. The participants were 15 ASD (mean age: 4.96 ± 1.10 years) typically developing (TD) 4.53 0.90 years). addition analyses of fixation time...
Nerve injury in somatosensory pathways may lead to neuropathic pain, which affects the life quality of ∼8% people. Long-term enhancement excitatory synaptic transmission along contributes pain. Caspase 3 (Casp3) plays a non-apoptotic role hippocampus and regulates internalization α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR) subunits. Whether Casp3-AMPAR interaction is involved maintenance peripheral hypersensitivity after nerve remained unknown. Here, we show that...
Cortex Moutan (root bark of Paeonia suffruticosa Andrew) and Radix Salviae miltiorrhizae rhizome Salvia miltiorrhiza Bunge) are two herbs widely used in traditional Chinese medicine (TCM) to treat cerebrovascular cardiovascular diseases. In clinical practice, these prescribed together. Studies on the pharmacokinetic interaction between active constituents (paeonol danshensu, respectively) can provide substantial foundation for understanding its mechanism empirical evidence support practice....
In the current study, functional near-infrared spectroscopy (fNIRS) was used to collect resting-state signals from 77 males with autism spectrum disorders (ASD, age: 6~16.25) and 40 typically developing (TD) (age: 6~16.58) in theory-of-mind (ToM) network. The graph theory analysis obtain brain network properties ToM network, multiple regression demonstrated that ASD showed a comparable global topology, similar age-related decrease medial prefrontal cortex area (mPFC) compared TD individuals....
The emergence of the neurodiversity movement has stimulated robust dialogues about autism-related terminology in Western societies, yet this subject remains largely unexplored China. Considering that distinct sociocultural contexts can engender diverse perceptions autism, it is crucial to foster discussions on appropriate language within Chinese framework. This will not only enhance understanding and acceptance but also contribute a more inclusive society for individuals autism spectrum. In...
Autism spectrum disorder (ASD) is a neurodevelopmental that affects about 2% of children. Due to the shortage clinicians, there an urgent demand for convenient and effective tool based on regular videos assess symptom. Computer-aided technologies have become widely used in clinical diagnosis, simplifying diagnosis process while saving time standardizing procedure. In this study, we proposed computer vision-based motion trajectory detection approach assisted with machine learning techniques,...
The present study is a cross-cultural comparison of typical dreams “being chased” between Tibetan and Han Chinese dreamers. research based on 208 interviews combined with responses to Dream Questionnaire. In total 569 subjects were involved in the project: 278 291 undergraduate college students. Results show an overall occurrence being-chased dream 90% sample population. Moreover, results also revealed that when being chased dreams, there significant difference chasing agents. addition, more...
This research addressed whether interactions with social robots could facilitate joint attention of the autism spectrum disorder (ASD). Two conditions initiators, namely 'Human' vs. 'Robot' were measured 15 children ASD and age-matched typically developing (TD) children. Apart from fixation gaze transition, a new longest common subsequence (LCS) approach was proposed to analyze eye-movement traces. Results revealed that showed deficits attention. Compared human agent, robot less fixations...
Objective To compare the efficacy of combination therapy single intravitreal injection ranibizumab with grid laser photocoagulation and only for treatment macular edema due to branch retinal vein occlusion (BRVO). Methods Forty eyes 40 patients BRVO at least 8 weeks duration were divided randomly into two groups. Group 1 20 received alone; 2 a dose followed by photocoagulation. Outcomes 1, 3, 6 12 months follow-up reported. Data collected on best corrected visual acuity (BCVA),...