A5100416831- Renal Diseases and Glomerulopathies
- Metabolomics and Mass Spectrometry Studies
- Health disparities and outcomes
- Liver Disease Diagnosis and Treatment
- Peripheral Neuropathies and Disorders
- Chronic Kidney Disease and Diabetes
- Chronic Disease Management Strategies
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Insurance, Mortality, Demography, Risk Management
- Myasthenia Gravis and Thymoma
- Analytical Chemistry and Chromatography
- Photonic and Optical Devices
- Traditional Chinese Medicine Studies
- Thyroid Cancer Diagnosis and Treatment
- Elbow and Forearm Trauma Treatment
- Inflammasome and immune disorders
- Nanopore and Nanochannel Transport Studies
- Systemic Lupus Erythematosus Research
- Phytochemistry and Biological Activities
- Advanced Glycation End Products research
- Salivary Gland Tumors Diagnosis and Treatment
- Diet, Metabolism, and Disease
- Orthopedic Surgery and Rehabilitation
- Platelet Disorders and Treatments
- Anesthesia and Pain Management
China Rehabilitation Research Center
2025
Second Xiangya Hospital of Central South University
2025
Xiangya Hospital Central South University
2025
First Affiliated Hospital of Xi'an Jiaotong University
2014-2024
Ministry of Education of the People's Republic of China
2024
Beijing Jiaotong University
2024
Peking University
2005-2024
Zhejiang Sci-Tech University
2020-2024
Hebei General Hospital
2024
Chengdu Second People's Hospital
2022-2024
Two decades of research indicate causal associations between social relationships and mortality, but important questions remain as to how affect health, when effects emerge, long they last. Drawing on data from four nationally representative longitudinal samples the US population, we implemented an innovative life course design assess prospective association both structural functional dimensions (social integration, support, strain) with objectively measured biomarkers physical health...
Aspirin-related gastrointestinal damage is of growing concern. Aspirin use modulates the gut microbiota and associated metabolites, such as bile acids (BAs), but how this impacts intestinal homeostasis remains unclear. Herein, using clinical cohorts aspirin-treated mice, we identified an microbe, Parabacteroides goldsteinii, whose growth suppressed by aspirin. Mice supplemented with P. goldsteinii or its BA metabolite, 7-keto-lithocholic acid (7-keto-LCA), showed reduced aspirin-mediated...
Abstract To evaluate the efficacy of pirfenidone in patients with rapidly progressive interstitial lung disease (RPILD) related to clinically amyopathic dermatomyositis (CADM), we conducted an open-label, prospective study matched retrospective controls. Thirty diagnosed CADM-RPILD a duration <6 months at Renji Hospital South Campus from June 2014 November 2015 were prospectively enrolled and treated target dose 1800 mg/d addition conventional treatment, such as glucocorticoid and/or...
Metabolic functions may operate as important biophysiological mechanisms through which social relationships affect health. It is unclear how embeddedness or the lack thereof related to risk of metabolic dysregulation. To fill this gap we tested effects integration on over time in a nationally representative sample older adults United States and examined population heterogeneity effects. Using longitudinal data from 4,323 aged 50 years Health Retirement Study latent growth curve models,...
// Yannan Zhao 1, * , Chengcheng Gong Zhonghua Wang 1 Jian Zhang Leiping Sheng Jun Cao Tao Ting Li Biyun and Xichun Hu Department of Medical Oncology, Fudan University Shanghai Cancer Center, College, University, 200032, China These authors have contributed equally to this work Correspondence to: Wang, email: wangbiyun0107@hotmail.com Hu, xchu2009@hotmail.com Keywords: metastatic breast cancer, hormone receptor positive, endocrine therapy, metformin, pre-treated Received: April 18, 2017...
Hepatocellular carcinoma (HCC) recurrence after liver transplantation (LT) is a major contributor to mortality. We developed prediction system for HCC patients before and LT. Data from with who underwent LT were retrospectively collected three specialist centres in China. Pre- post-operative variables selected using support vector machine, random forest, logistic regression (LR). Then, pre- models machine learning methods: LR, stacking, two survival-based approaches. Models evaluated seven...
Selecting interventions for patients with solitary hepatocellular carcinoma (HCC) remains a challenge. Despite gross classification being proposed as potential prognostic predictor, its widespread use has been restricted due to inadequate studies sufficient patient numbers and the lack of established mechanisms. We sought investigate impacts on HCC different subtypes assess their corresponding molecular landscapes.A prospective cohort 400 who underwent hepatic resection was reviewed analysed...
The number of international students attending U.S. colleges and universities has increased considerably over the past decade, adaptation these is an important concern in cross-cultural research. Using survey data collected from a sample 169 university, this study examines temporal patterns students’ psychological socio-cultural adaptation. Theresults suggest two-phase U-curved process adaptation, with most obvious culture shock occurring during student’s first nine to 24 months residence....
Direct infusion-mass spectrometry (DI-MS) currently serves as an alternative analytical tool for metabolomics owing to the unique high-throughput advantage. Except inherent shortcoming at a significant matrix effect, there are two other primary technical obstacles dampening its wide applications, such data alignment and structural annotation. To address these obstacles, novel strategy termed DI-three-dimensional-MS (DI-3D-MS) was proposed here, chemome comparison among several confusing...
This study aimed to investigate the protective effects of fleshes from two Actinidia chinensis (ACF), pericarps A. (ACP), and with (ACFP) on high fructose (HF)-instigated dyslipidemia, hepatic steatosis, oxidative stress, insulin resistance, fatty acid metabolism disorders in rats. In general, above abnormalities were improved after 10 weeks intervention ACF, ACP, ACFP. Especially, ACFP considerably ameliorated HF-induced abnormal changes body weight gain, serum TC, TG, LDL-C HDL-C levels,...