A5100430800- Glaucoma and retinal disorders
- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Corneal surgery and disorders
- Intraocular Surgery and Lenses
- Retinal and Optic Conditions
- Ocular Diseases and Behçet’s Syndrome
- Ocular and Laser Science Research
- Traumatic Ocular and Foreign Body Injuries
- Ophthalmology and Eye Disorders
- Retinal Development and Disorders
- Ophthalmology and Visual Impairment Studies
- Ocular Surface and Contact Lens
- Advanced Glycation End Products research
- Systemic Lupus Erythematosus Research
- CNS Lymphoma Diagnosis and Treatment
- Retinal and Macular Surgery
- Connective tissue disorders research
- MicroRNA in disease regulation
- Facial Trauma and Fracture Management
- Contact Dermatitis and Allergies
- Photoacoustic and Ultrasonic Imaging
- Laser Material Processing Techniques
- Acute Ischemic Stroke Management
- Connexins and lens biology
YangPu Geriatric Hospital
2023
Weatherford College
2022
Sichuan University
2022
West China Hospital of Sichuan University
2022
Sun Yat-sen University
2018-2022
PLA Army Engineering University
2022
Guiyang Medical University
2021
Zhongshan Hospital
2018-2020
Fudan University
2018-2020
The First Affiliated Hospital, Sun Yat-sen University
2018-2020
Abstract Background To describe implementation and first-year screening results of the first Chinese telehealth system for diabetic retinopathy (DR) - Beixinjing Community Diabetic Retinopathy Telehealth (BCDRT). Methods BCDRT was based on acquisition adequate digital retinographs, secure transmission, storage retrieval participants' data reader-generated medical reports. Local residents meeting inclusion criteria were enrolled into beginning in 2009. Participants recommended further...
Purpose: To evaluate the intraocular pressure (IOP)-lowering effect of combination phacoemulsification with lens implantation (PEI), goniosynechialysis (GSL), and goniotomy (GT) in eyes advanced primary angle-closure glaucoma (PACG) cataract. Design: Multicenter observational study. Methods: We enrolled 83 patients PACG who received combined PEI+GSL+GT at 8 ophthalmic institutes. Each patient was assessed before treatment 1, 7 days, 3, 6, 12 months postsurgery. The criteria for complete...
To measure the retinal thickness of posterior pole in healthy Chinese subjects using a analyzer and to compare thicknesses between different age, gender, refractive error groups.Between February 2002 September 2004, (age range, 21-50 years), underwent measurements visual acuity, error, intraocular pressure, with RTA, as well ophthalmoscopy slit lamp examinations. Eleven parameters were directly derived from reports RTA measurement. The average value each parameter was compared male female...
Purpose . To describe clinical features and to analyze visual outcome of ocular trauma in Cangzhou 2012–2015, China. Methods A retrospective study cases admitted Central Hospital from January 2012 till December 2015 was performed. Results This included a total 507 eyes 478 patients. Four hundred (83.7%) patients were male, with male-to-female ratio 5.1 : 1. Mean age was<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"...
Background Subjective functional outcomes measurements, such as vision health-related quality of life (VRQoL) and self-rated satisfaction measures can provide helpful multidimensional health information that is more comprehensive than traditional objective measures, best corrected visual acuity (BCVA). The purpose this study to demonstrate 3-year longitudinal postoperative VRQoL changes after rhegmatogenous retinal detachment (RRD) surgery. Methodology/Principal Findings A prospective case...
Purpose: Choroidal neovascularization (CNV) is a common pathological change of various ocular diseases that causes serious damage to central vision. Accumulated evidence shows microRNAs (miRNAs) are closely related with the regulation endothelial metabolism, which plays crucial roles in angiogenesis. Here, we investigate molecular mechanism underlying glutamine metabolism by miR-376b-3p progression CNV. Methods: Human retinal microvascular cells (HRMECs) were transfected control or mimics,...
Pigment epithelium-derived factor (PEDF) is expressed in several normal organs and identified as an inhibitor of neovascularization. In the present study, we investigated effect PEDF vitro model ocular choroidal neovascularization.Microdissection was used to isolate human endothelial cells (CECs), followed by use superparamagnetic beads (Dynabeads) coated with CD31 antibody, which selectively binds cell surface. The mitogenic motogenic effects vascular growth (VEGF) on cultured capillary...
Intraocular pressure (IOP) generates stress and strains in the laminar cribrosa sclera, which may affect development progression of glaucoma. Scleral stiffness material components have changed under elevated IOP. However, detailed components' changes hypertensive sclera are not well understood. In this study, we aimed to investigate main scleral extracellular matrix (ECM) metalloproteinase 2 (MMP2), their relationship with time chronic IOP Sprague-Dawley rats. Ocular hypertension model was...
Primary angle-closure glaucoma (PACG) has a high prevalence and blinding rate across Asia. The first-line treatment of PACG is surgery, phacotrabeculectomy remains the mainstream surgery for advanced PACG. However, it may cause vision-threatening complications with long learning curve. Minimally invasive been gradually used in combined cataract achieved efficacy without excessive injury, which goniotomy most commonly performed. Therefore, this study aimed to conduct multicentre,...
Purpose . To investigate the biometric characteristics of Chinese patients with a history acute angle closure (AAC). Methods In this clinic-based, retrospective, observational, cross-sectional study, parameters eyes were acquired from general population adults. The crowding value (defined as lens thickness (LT); central corneal (CCT); anterior chamber depth (ACD)/axial length (AL)) was calculated for each patient. Logistic regression analysis performed to identify risk factors AAC. Receiver...
Objective To design the community-based tele-screening system for diabetic retinopathy and evaluate feasibility of it.Methods Cross-sectional study.The was based on non-mydriatic digital eye fundus camara photography computer network technology.109 type 2 diabetes mellitus residents were randomly selected evaluation,which included:1)The consistency far visual acuity examined by an ophthalmologist a trained inspector,evaluated paired t-sample test;the diagnosis traditional screening method...
Background Diabetic retinopathy (DR) and diabetic macular edema (DME) are common complications of diabetes.Currently abroad study results incidence risk factors DR DME in type 2 diabetes population varied largely depending on the ethnical difference.However, relevant epidemiological is rare China. Objective This survey was to assess 5-year Chinese patients. Methods A prospective cross-sectional performed under informed consent patients.An for organized carried out 805 patients...
Abstract Rationale: Central retinal artery occlusion and branch (BRAO) result in partial or complete ischemia sudden loss of vision; to date there is no effective therapy for central BRAO. Transluminal Nd:YAG laser embolysis (TYE) could represent a therapeutic approach vascular occlusive diseases. Patient concerns: We report 2 cases with BRAO, 1 inferor-temporal superor hemiretinal All the patients complained history blurry vision impaired visual field had visible embolus within...
Background Long-term study on type 2 diabetes discovered that some patients with diabetic retinopathy (DR) or macular edema (DME) appear regression of lesions without invasive ocular intervention but only systemic medication.These mechanisms remain unclear. Objective This was to survey the rate and relevant factors DR DME in patients. Methods A prospectively observational performed.Totally 778 who met inclusion criteria participated this consecutive 5-year survey.The demographic...
Aldehyde dehydrogenase 2 plays a pivotal role in detoxifying aldehydes, and our previous study revealed that aldehyde could alleviate diabetic retinopathy-associated damage. We aimed to characterize the potential of keratopathy. Twenty-four rats with streptozotocin-induced (60 mg/kg, single intraperitoneal injection) type 1 diabetes mellitus (T1DM) were divided T1DM group + Alda1 (an activator 2) (5 mg/kg/d, injection, 1/2/3 months), while an additional 12 healthy served as control group....
Background In recent years, some researches show that getting younger over the diabetes mellitus (DM) was an obrious trend. But studies of early diabetic retinopathy in young people with were few. Both patients and doctors did not put enough importance on it. Objective This study to evaluate earlier dynamic changes retina morphology function caused by type 2 DM population. Methods A cohort designed. One hundred thirty-six who initially diagnosed as Cangzhou Central Hospital...
Background Some diabetic patients with well controlled blood glucose still had retinopathy(DR). The risk factor of DR progression in Mongoloid was not clear. Objective This study to assess the 5-year incidence and factors type 2 glucose. Methods A prospective performed under informed consent patients.453 glycosylated hemoglobin A1c (HbA1c)<7.0% Shanghai xinjing Community from 2007 2012 were included this study.The baseline survey started final ended 2012.The comprehensive...
Objective To observe the clinical efficacy of enhanced external counterpulsation (ECP) in treatment non-proliferative diabetic retinopathy (NPDR). Methods It was a case-control study. 83 patients (166 eyes) NPDR were randomly divided into ECP group (ECP group) and conventional therapy (drug by date visit odd even number, each with 42 84 eyes 41 82 respectively. The blood glucose, glycated hemoglobin (HbA1c), low-density lipoprotein (LDL-C), corrected visual acuity, stages (DR)...