A5045641131- Genetic factors in colorectal cancer
- Colorectal Cancer Screening and Detection
- Inflammatory Bowel Disease
- Liver Disease and Transplantation
- Colorectal and Anal Carcinomas
- Gastric Cancer Management and Outcomes
- PI3K/AKT/mTOR signaling in cancer
- Immune Response and Inflammation
- Archaeological and Geological Studies
- Immune cells in cancer
- Liver Disease Diagnosis and Treatment
- Celiac Disease Research and Management
- Blood transfusion and management
- Medical and Biological Ozone Research
- Dialysis and Renal Disease Management
- Medieval Architecture and Archaeology
- Intestinal Malrotation and Obstruction Disorders
- Esophageal Cancer Research and Treatment
- Blood donation and transfusion practices
- Congenital gastrointestinal and neural anomalies
- Medicine and Dermatology Studies History
- Neuroendocrine Tumor Research Advances
- Appendicitis Diagnosis and Management
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Archaeological and Historical Studies
Hospital de Sant Pau
2009-2024
Universitat Autònoma de Barcelona
2009-2021
Hospital Clínic de Barcelona
2013
Centro de Investigación Biomédica en Red
2009
Hospital General Universitario Gregorio Marañón
2008
The hemoglobin threshold for transfusion of red cells in patients with acute gastrointestinal bleeding is controversial. We compared the efficacy and safety a restrictive strategy those liberal strategy.
Objective Outside clinical trials, the effectiveness of chromoendoscopy (CE) for long-standing IBD surveillance is controversial. We aimed to assess CE neoplasia detection and characterisation, in real-life. Design From June 2012 2014, patients with were prospectively included a multicentre cohort study. Each colonic segment was evaluated white light followed by 0.4% indigo carmine CE. Specific lesions' features recorded. Optical diagnosis assessed. Dysplasia rate between expert non-expert...
Abstract During the flare-ups of Crohn’s disease (CD) patients, circulating leukocytes actively migrate toward inflamed sites. remission, lack symptoms does not necessarily imply immunological remission. To decipher inflammatory mechanisms still operating during CD we compared expression chemokine receptors on monocytes from and healthy donors (HD), how these differences could modulate monocyte maturation cytokine production. Flow cytometry analysis showed a higher CCR5 patients than those...
Circulating monocytes from active ulcerative colitis (UC) patients produced high levels of tumor necrosis factor-alpha(TNFα) and interleukin(IL)-6 after Toll-like receptors (TLR) stimulation. Since platelets (PLT) can bind to leukocytes, thereby decreasing inflammatory cytokine production, UC may exhibit different monocyte-platelet complexes depending on disease activity.We compared among healthy donors, (onset flare relapse), inactive the presence circulating (CD14+PLT+) membrane CD162...
Crohn's disease [CD] is a chronic, systemic inflammatory characterised by periods of remission and flare-ups. It has been associated with disturbed gastrointestinal barrier function, an increase in the transport luminal contents into tissue, lower immune tolerance.Peripheral blood samples were collected from healthy controls 33 adult active flare-up CD patients. We classified patients as onset or relapse subjects, according to days evolution. Plasma levels lipopolysaccharide-binding protein...
Abstract Background The “diagnose-and-leave-in” policy has been established to reduce the risks and costs related unnecessary polypectomies in average-risk population. In individuals with Lynch syndrome, owing accelerated carcinogenesis, general recommendation is remove all polyps, irrespective of size, location, appearance. We evaluated feasibility safety diagnose-and-leave-in strategy syndrome. Methods performed a post hoc analysis based on per-polyp data from randomized, clinical trial...
Background: Computer-aided artificial intelligence-based polyp detection systems (CADe) have demonstrated to increase small during colonoscopy in the average-risk population. Lynch syndrome (LS) represents an ideal target population for CADe since adenomas, primary cancer precursor lesions, are characterized by their size and higher likelihood of displaying advanced histology. The potential clinical value LS remains unknown.Methods: A prospective, multicenter parallel, randomized control...
Adenomas in Lynch syndrome (LS) have an accelerated progression to colorectal cancer. Despite low evidence, clinical guidelines recommend using high-definition and pan-chromoendoscopy (CE) for surveillance LS. We aimed compare the adenoma detection rate (ADR) between white-light endoscopy (WLE) CE individuals with
Introducción: El esófago de Barrett (EB) es controlado periódicamente con endoscopia toma biopsias para detectar displasia. Sin embargo, las muestras son poco representativas y gran variabilidad en su interpretacion. Para evitar el riesgo degeneración, se han desarrollado técnicas ablativas eficacia variable no exentas complicaciones. Una alternativa segura podría ser la ligadura sin resección (LSR). Objetivo: Evaluar forma prospectiva seguridad LSR erradicación completa del EB corto...
To evaluate the adequacy of a “diagnose and disregard” strategy for rectosigmoid (RS) diminutive polyps in Lynch syndrome patients.