A5010853718- Astrophysics and Cosmic Phenomena
- Dark Matter and Cosmic Phenomena
- Neutrino Physics Research
- Advanced X-ray Imaging Techniques
- Radio Astronomy Observations and Technology
- Particle physics theoretical and experimental studies
- X-ray Spectroscopy and Fluorescence Analysis
- Laser-Plasma Interactions and Diagnostics
- Gamma-ray bursts and supernovae
- Astronomical Observations and Instrumentation
- Particle Detector Development and Performance
- Atmospheric Ozone and Climate
- Advanced X-ray and CT Imaging
- Calibration and Measurement Techniques
- Crystallography and Radiation Phenomena
- Advancements in Photolithography Techniques
- High-pressure geophysics and materials
- Diamond and Carbon-based Materials Research
- Astrophysical Phenomena and Observations
- Pulsars and Gravitational Waves Research
- Medical Imaging Techniques and Applications
- Advanced Electron Microscopy Techniques and Applications
- Precipitation Measurement and Analysis
- Photocathodes and Microchannel Plates
- Nuclear Physics and Applications
Karlsruhe Institute of Technology
2016-2025
Istituto Nazionale di Fisica Nucleare, Sezione di Lecce
2023
Université Paris Cité
2017
Centre National de la Recherche Scientifique
2017
Consejo Nacional de Investigaciones Científicas y Técnicas
2011-2017
Universidad Nacional de La Plata
2011-2017
Institut National de Physique Nucléaire et de Physique des Particules
2017
Sorbonne Université
2017
Laboratoire de Physique Nucléaire et de Hautes Énergies
2017
University of Bucharest
2016
Abstract X-ray chest radiography is an inexpensive and broadly available tool for initial assessment of the lung in clinical routine, but typically lacks diagnostic sensitivity detection pulmonary diseases their early stages. Recent dark-field (XDF) imaging studies on mice have shown significant improvements imaging-based diagnostics. Especially case diagnosis chronic obstructive disease (COPD), XDF clearly outperforms conventional radiography. However, a translation this technique towards...
Differential phase contrast X-ray imaging (DPCI) has gained a lot of interest in the past years. It is based on grating interferometry and image quality strongly dependant quality. Periodic line space structures with periods micron range are required for source absorption grating. In case energies > 30 keV their height should be larger than 100 μm resulting aspect ratios more 100. Deep lithography gold electroforming (LIGA technology) used to fabricate these challenging structures. After...
Abstract The possibility to perform high-sensitivity X-ray phase-contrast imaging with laboratory grating-based computed tomography (gbPC-CT) setups is of great interest for a broad range high-resolution biomedical applications. However, achieving high sensitivity gbPC-CT still poses challenge because several factors such as the reduced flux, polychromaticity spectrum and limited coherence source reduce performance in comparison at synchrotron facilities. In this work, we present our...
X-ray grating-based interferometry promises unique new diagnostic possibilities in medical imaging and materials analysis. To transfer this method from scientific laboratories or small-animal applications to clinical radiography applications, compact setups with a large field of view (FoV) are required. Currently the FoV is limited by grating area, which restricted due complex manufacturing process. One possibility increase tiling individual tiles create one area mounted on carrier...
An aerosol jet printing (AJP) head built on top of precise motion systems can provide positioning deviation down to 3 μm, areas as large 20 cm × 30 cm, and five-axis freedom movement. Typical uses AJP are 2D complex or flexible substrates, primarily for applications in printed electronics. Nearly all commercially available inks designed optimized reach desired electronic properties. In this work, we explore the 3D free-standing pillar arrays. We utilize aryl epoxy photopolymer ink coupled...
X-ray imaging using a Talbot-Lau interferometer, consisting of three binary gratings, is well-established approach to acquire x-ray phase-contrast and dark-field images with polychromatic source. However, challenges in the production high aspect ratio gratings limit construction compact setup for energies. In this study we consider use phase triangular-shaped structures an interferometer show that such can yield visibilities significantly shorter propagation distances than conventional...
The x-ray dark-field contrast accessible via grating interferometry is sensitive to features at length scales well below what resolvable by a detector system. It commonly explained as arising from small-angle scattering (SAXS), and can be implemented both synchrotron beamlines with low-brilliance sources such tubes. Here, we demonstrate that for tube based setups the underlying process of image formation fundamentally different. For focal spots or pixels comprise multiple periods, show...
Grating based X-ray differential phase contrast imaging (DPCI) allows for high of materials with similar absorption characteristics. In the last years' publications, small animals or parts human body like breast, hand, joints blood vessels have been studied. Larger object s could not be investigated due to restricted field view limited by available grating area. this paper, we report on a new stitching method increase area significantly: individual gratings are merged carrier substrate....
An array of compound refractive X-ray lenses (CRL) with 20 × lenslets, a focal distance 20cm and visibility 0.93 is presented. It can be used as Shack-Hartmann sensor for hard X-rays (SHARX) wavefront sensing permits true single-shot multi-contrast imaging the dynamics materials spatial resolution in micrometer range, sensitivity on nanosized structures temporal microsecond scale. The object’s absorption its induced shift assessed simultaneously together information from diffraction...
We report on the implementation and characterization of grating interferometry operating at an x-ray energy 183 keV. With possibility to use this technique high energies, bigger specimens could be studied in a quantitative way. Also, imaging strongly absorbing will benefit from advantages phase dark-field signals provided by interferometry. However, especially these photon energies performance absorption becomes key point quality system, because lines need keep their small width couple...
Biodiesel production from first-generation feedstock has shown a strong correlation with the increase in deforestation and necessity of larger areas for land farming. Recent estimation European Federation Transport Environment evidenced that since 2000s decade, an area equal to Netherlands was deforested supply global biodiesel demand, mainly originating feedstock. Nevertheless, is renewable, it can be greener source energy than petroleum. A promising approach make independent large farming...
Grating based X-ray phase contrast imaging is on the verge of being applied in clinical settings. To achieve this goal, compact setups with high sensitivity and dose efficiency are necessary. Both can be increased by eliminating unwanted absorption beam path, which mainly due to grating substrates. Fabrication gratings via deep lithography address issue replacing commonly used silicon substrate materials lower that fulfill certain boundary conditions. Gratings were produced both graphite...
Different approaches of 2D lens arrays as Shack–Hartmann sensors for hard X-rays are compared. For the first time, a combination (SHSX) with super-resolution imaging approach to perform multi-contrast is demonstrated. A diamond employed well known test object. The interleaving has great potential overcome array limitation given by two-photon polymerization lithography. Finally, radiation damage induced continuous exposure an SHSX prototype white beam was studied showing good performance...
X-ray grating interferometry is one among various methods that allow extracting the so-called phase and visibility contrasts in addition to well-known transmission images. Crucial achieving a high image quality are absorption gratings employed. Here, we present an in-depth analysis of how type lamella heights influence final Benchmarking two different designs, show frequently used proxy for quality, grating's visibility, insufficient predict contrast-to-noise ratios (CNRs). Presenting scans...
Refractive X-ray lenses are in use at a large number of synchrotron experiments. Several materials and fabrication techniques available for their production, each having own strengths drawbacks. We present grating interferometer the quantitative analysis single refractive employ it study beryllium point focus lens polymer line lens, highlighting differences outcome methods. The residuals fit to phase gradient used quantify local defects, while shape aberrations quantified by decomposition...
Grating-based x-ray differential phase-contrast imaging (DPCI) is capable of acquiring information based on phase-shift and dark-field signal, in addition to conventional absorption-contrast. Thus DPCI gives an advantage investigate composite materials with component wise similar absorption properties like soft tissues. Due technological challenges fabricating high quality gratings over a large extent, the field view (FoV) systems limited grating area couple square centimeters. For many...
Abstract The KATRIN experiment is designed for a direct and model-independent determination of the effective electron anti-neutrino mass via high-precision measurement tritium $$\upbeta $$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:mi>β</mml:mi> </mml:math> -decay endpoint region with sensitivity on $$m_\nu <mml:msub> <mml:mi>m</mml:mi> <mml:mi>ν</mml:mi> </mml:msub> 0.2 $$\hbox {eV}/\hbox {c}^2$$ <mml:mrow> <mml:mtext>eV</mml:mtext> <mml:mo>/</mml:mo> <mml:msup>...
We report on an x-ray cone-beam differential phase-contrast computed laminography (DPC-CL) method for tomographic reconstruction of thin and lamellar objects. describe the specific scan geometry DPC-CL, which consists a Talbot-Lau grating interferometer lab-based tube source, derive filtered back-projection (FBP) algorithm. The experimental results flat sphere phantom piece ham demonstrate validity proposed technique. existing DPC-CL methods are based synchrotron sources parallel-beam...
X-ray differential phase-contrast imaging (DPCI) using a Talbot–Lau interferometer at conventional tube source has continuously found applications since its first demonstration. It requires high aspect ratio grating structures with feature size in the micrometer range that are fabricated lithographie, galvanik und abformung technology. To overcome current limitation area, an exposure strategy—continuous exposure—has been developed. In this case, mask is fixed respect to synchrotron beam and...
Abstract The KArlsruhe TRItium Neutrino experiment (KATRIN) aims to determine the effective electron (anti)-neutrino mass with a sensitivity of 0.2eV/c $$^2$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:msup> <mml:mrow /> <mml:mn>2</mml:mn> </mml:msup> </mml:math> by precisely measuring endpoint region tritium $$\beta $$ <mml:mi>β</mml:mi> -decay spectrum. It uses tandem electrostatic spectrometers working as magnetic adiabatic collimation combined an (MAC-E) filters. In...
The trigger system for the AUGER fluorescence detector is presented. main goals of design were low price, high flexibility trigger, reliability and good testability even at remote operation. simulation all boards using VHDL tools resulted in a which optimal with respect to these highly independent existing commercial solutions. large-scale integration modern FPGAs yielded massive parallel recognition tracks suppression background. readout control carried out by cost PCs under LINUX operating system.
Single-shot grating-based phase-contrast imaging techniques offer additional contrast modalities based on the refraction and scattering of X-rays in a robust versatile configuration. The utilization single optical element is possible such methods, allowing shortening acquisition time increasing flux efficiency. One ways to upgrade single-shot utilize customized components, as two-dimensional (2D) X-ray gratings. In this contribution, we present achievements development 2D gratings with UV...
One of the types negative tone photoresists is composed at least a catalyst, solvent, and epoxy resin. This primary raw material for lithography technology. To ensure high-quality pattern transfer in process, it crucial to control properties photoresist. In this work, set resins based on Bisphenol-A were synthesized. The obtained have been characterized regarding chain size its derivative products. As second step, an epoxidation reaction was performed groups quantified. profile resins, by...