A5074084372- Leptospirosis research and findings
- Antibiotic Resistance in Bacteria
- Bacterial biofilms and quorum sensing
- Vibrio bacteria research studies
- Antimicrobial Resistance in Staphylococcus
- Bacterial Identification and Susceptibility Testing
- Zoonotic diseases and public health
- Salmonella and Campylobacter epidemiology
- Yersinia bacterium, plague, ectoparasites research
- Mycobacterium research and diagnosis
- Viral Infections and Vectors
- Bacterial Infections and Vaccines
- Listeria monocytogenes in Food Safety
- Clostridium difficile and Clostridium perfringens research
- Prion Diseases and Protein Misfolding
- Antibiotic Use and Resistance
- Enterobacteriaceae and Cronobacter Research
- Neurological diseases and metabolism
- Probiotics and Fermented Foods
- Reproductive tract infections research
- Pneumonia and Respiratory Infections
- Streptococcal Infections and Treatments
- Syphilis Diagnosis and Treatment
- Identification and Quantification in Food
- Botulinum Toxin and Related Neurological Disorders
Independent Sector
2024
Semmelweis University
2009-2020
National Center for Epidemiology
2004-2008
National Public Health and Medical Officer Service
1999-2001
Budapest Institute
1999-2001
Czech Academy of Sciences, Institute of Microbiology
1961-1962
Eötvös Loránd University
1960-1961
ABSTRACT The implementation of routine whole-genome sequencing (WGS) promises to transform our ability monitor the emergence and spread bacterial pathogens. Here we combined WGS data from 308 invasive Staphylococcus aureus isolates corresponding a pan-European population snapshot, with epidemiological resistance data. Geospatial visualization is made possible by generic software tool designed for public health purposes that available at project URL (...
To investigate the molecular epidemiology of ciprofloxacin-resistant CTX-M-15-producing Klebsiella pneumoniae epidemic clones (ECs) isolated from six nosocomial outbreaks and sporadic cases during 2005 in Hungary.Two hundred eighty-one extended-spectrum beta-lactamase (ESBL)-producing K. clinical isolates collected 41 centres were submitted to National ESBL Reference Laboratory for further investigations. Of 281 strains, 75 proved be SHV producers, whereas 6 ciprofloxacin-susceptible...
ABSTRACT Ten multidrug-resistant Pseudomonas aeruginosa strains producing VIM-1-like acquired metallo-β-lactamases (MBLs), isolated from four European countries (Greece, Hungary, Italy, and Sweden), were analyzed for genetic relatedness by several methodologies, including fliC sequence analysis, macrorestriction profiling of genomic DNA pulsed-field gel electrophoresis (PFGE), random amplification polymorphic (RAPD), multilocus typing (MLST). The approaches yielded consistent results overall...
It is well-established that the spread of many multidrug-resistant (MDR) bacteria predominantly clonal. Interestingly international clones/sequence types (STs) most pathogens emerged and disseminated during last three decades. Strong experimental evidence from multiple laboratories indicate diverse fitness cost associated with high-level resistance to fluoroquinolones contributed selection promotion clones/STs hospital-associated methicillin-resistant Staphylococcus aureus (HA-MRSA),...
Journal Article Immunologic and Molecular Biologic Studies of Prion Proteins in Bovine Spongiform Encephalopathy Get access Stanley B. Prusiner, Prusiner Reprints or correspondence: Dr. Dept. Neurology HSE-781, University Californi, San Francisco, CA 94143-0518. Search for other works by this author on: Oxford Academic PubMed Google Scholar Miklós Füzi, Füzi Michael Scott, Scott Dan Serban, Serban Hana Albert Taraboulos, Taraboulos Jean-Marc Gabriel, Gabriel Gerald A. H. Wells, Wells John W....
PER-1 extended-spectrum beta-lactamase-producing Pseudomonas aeruginosa clinical isolates from Budapest, Hungary, and Belgrade, Serbia, were characterized by molecular methods. Two PER-1-positive recovered sporadic cases in Budapest a small cluster of infections involving four patients identified at Belgrade hospital. A class 1 integron harbouring bla(OXA-2)beta-lactamase gene other cassettes was detected both the isolates. The two P. also carried another containing bla(OXA-74),...
A VIM metallo-beta-lactamase-producing Aeromonas hydrophila strain carrying an integron-borne bla(VIM-4) gene was isolated from a cirrhotic patient's fecal sample in Budapest hospital. The variable region of this integron is identical with that previously characterized Pseudomonas aeruginosa clinical isolates Pécs southern Hungary.
The first integron-borne metallo-beta-lactamase gene was isolated in Hungary. bla(VIM-4) is located on a class 1 integron that also carries novel bla(OXA)-like gene. harbored by serotype O12 Pseudomonas aeruginosa strain and shows high structural similarity to integrons Greece Poland.
It is widely accepted that favorable fitness in commensal colonization one of the prime facilitators clonal dissemination bacteria. The question arises as to what kind advantage may be wielded by uropathogenic strains two predominant fluoroquinolone- and multidrug-resistant groups E. coli—ST131-H30 ST1193, which has permitted their unprecedented pandemic-like global expansion last few decades. colonization-associated genes’ content, carriage low-cost plasmids, integrons with weak promoters...
VIM metallo-beta-lactamase-producing serotype O11 or O12 Pseudomonas aeruginosa isolates infecting colonizing 19 patients from seven hospitals in Hungary were characterized between October 2003 and November 2005. Macrorestriction analysis revealed the involvement of three different towns northwest an outbreak caused by VIM-4-producing P. aeruginosa.
From the Central-East European region first VIM metallo- β -lactamase (MBL) producing Pseudomonas aeruginosa strains were published from Croatia, Poland and Hungary. The aim of this study was to assess contribution MBL-production carbapenem-resistance among P. clinical isolates in Military Medical Academy (MMA) Belgrade, Serbia between August 2004 September 2007. Only one isolate with strain number 722 proved MBL-positive that harboured a novel class 1 integron blaVIM-2 -like cassette...
Silver is used extensively in both hospitals and outpatient clinics as a disinfectant coating agent on various devices. Resistance to silver was recently reported an emerging problem Enterobacteriaceae. Multidrug-resistant high-risk clones of Klebsiella pneumoniae are common causes serious healthcare-associated infections worldwide posing threat patients. In this study, we investigated the capacity (CG14/15 CG258) minor clone strains K. develop resistance silver. induced vitro...
Background Antibiotic prescription practices differ between countries, influencing regional antimicrobial resistance prevalence. However, comparisons of clonal diversity among resistant bacteria in countries with different prescribing are rare. The rise fluoroquinolone-resistant Escherichia coli (FQREC), often multidrug-resistant, exacerbates global antibiotic resistance. Unlike the USA, antibiotics commonly dispensed Iraq without prescriptions, leading to widespread overuse and misuse. This...