A5007494043- Glioma Diagnosis and Treatment
- Breast Cancer Treatment Studies
- Brain Metastases and Treatment
- Prostate Cancer Treatment and Research
- Prostate Cancer Diagnosis and Treatment
- Advanced Radiotherapy Techniques
- Cancer Genomics and Diagnostics
- Breast Lesions and Carcinomas
- Lung Cancer Treatments and Mutations
- Management of metastatic bone disease
- Cancer Diagnosis and Treatment
- Lymphoma Diagnosis and Treatment
- Chronic Lymphocytic Leukemia Research
- Lung Cancer Diagnosis and Treatment
- Acute Lymphoblastic Leukemia research
- Radiation Therapy and Dosimetry
- Metastasis and carcinoma case studies
- Radiomics and Machine Learning in Medical Imaging
- Hepatocellular Carcinoma Treatment and Prognosis
- Lung Cancer Research Studies
- Radiopharmaceutical Chemistry and Applications
- Bladder and Urothelial Cancer Treatments
- Ultrasound and Hyperthermia Applications
- Memory and Neural Mechanisms
- Cancer-related cognitive impairment studies
Centro di Riferimento Oncologico
2005-2022
Istituti di Ricovero e Cura a Carattere Scientifico
2020-2022
National Cancer Institute
2017
Azienda Ospedaliera Santa Maria Degli Angeli
2003
Decades of therapeutic and molecular refinements, the prognosis patients with glioblastoma (GBM) still remains unfavorable. Integrative clinical studies allow a better understanding natural evolution GBM. To assess independent predictors overall survival (OS) progression free (PFS) clinical, surgical, radiological variables were evaluated. A novel preoperative volumetric magnetic resonance imaging (MRI) Index for tumor in GBM was investigated.A cohort 195 cases operated newly analyzed....
Despite recent discoveries in genetics and molecular fields, glioblastoma (GBM) prognosis still remains unfavorable with less than 10% of patients alive 5 years after diagnosis. Numerous studies have focused on the research biological biomarkers to stratify GBM patients. We addressed this issue our study by using clinical/molecular image data, which is generally available Neurosurgical Departments order create a prognostic score that can be useful undergoing surgical resection. By random...
Many different therapeutic options are available for locally recurrent prostate cancer (PCa).However, standard treatment has not yet been established.We conducted a partial re-irradiation (PPR) program the of isolated and limited-size intraprostatic recurrences, in patients who previously underwent external beam radiation therapy (EBRT) as primary prostatic (PCa).The analysis this experience terms feasibility, toxicity, efficacy is reported.The inclusion criteria retrospective were: previous...
Aims and background The present study evaluated toxicity, local control, survival in patients with relapsed high-grade glioma after surgery external beam radiation therapy treated re-operation GliaSite brachytherapy. Methods Between 2006 2008, 15 recurrent underwent Ten were males 5 females. Median age was 40 years (range, 20–71). Karnofsky performance status ≥70. All but one received irradiation of the surgical cavity wall at dose 4500 cGy a depth 1 cm. Results No severe acute side effects...
A group of 38 patients with a median age 70 years and chronic lymphocytic leukemia (CLL) were treated using cobalt 60 U or 6-MeV linear accelerator. direct field two opposite fields covered the palpable spleen area in most patients. 100 cGy administered weekly for total dose 10 Gy, given over weeks. The stage arrangement (according to Rai) 32 evaluable was as follows: Stage I: 11 patients, II: nine III: three IV: Patients Stages I II when symptomatic. Twenty-five (78%) achieved hematologic...
The present study evaluated toxicity, local control, and survival in patients with relapsed high-grade glioma after surgery external beam radiation therapy treated re-operation GliaSite brachytherapy.Between 2006 2008, 15 recurrent underwent brachytherapy. Ten were males 5 females. Median age was 40 years (range, 20-71). Karnofsky performance status ≥70. All but one received irradiation of the surgical cavity wall at dose 4500 cGy a depth 1 cm.No severe acute side effects observed during...
// Chiara Zanusso 1 , Roberto Bortolus 2 Eva Dreussi Jerry Polesel 3 Marcella Montico Erika Cecchin Sara Gagno Flavio Rizzolio Mauro Arcicasa Giacomo Novara 4 Giuseppe Toffoli Experimental and Clinical Pharmacology Unit, National Cancer Institute, Aviano, PN, Italy Department of Radiation Oncology, Epidemiology Biostatistics Surgery, Gastroenterology, University Padua, Correspondence to: Toffoli, email: gtoffoli@cro.it Keywords: prostate cancer, polymorphisms, biochemical recurrence, overall...
Background. The efficacy and toxicity of total body irradiation (TBI) in patients with chronic lymphocytic leukemia (CLL) low grade non-Hodgkin's lymphomas (NHL) were evaluated. Methods. Between January 1984 September 1992, 81 consecutive patients, 40 affected CLL 41 NHL, symptomatic Stage III IV disease, treated TBI followed by prednimustine. was given a 6 MV linear accelerator, applying two opposite alternating fields, including body, fractions 15 cGy per week (3-day interval). A dose 150...
The aim of this study was to prospectively evaluate the safety and oncologic outcomes multimodal treatment in high risk-locally advanced prostate cancer patients (PCa).High-risk-locally without distant metastases before radical prostatectomy (RP) were included. Adjuvant high-dose intensity-modulated radiation therapy (IMRT) with concurrent docetaxel long-term androgen-deprivation (ADT) started after 3-6 months from RP. ADT maintained for two years. Acute late toxicity evaluated Common...
From March 1985 to July 1989, 22 patients with unresectable pancreatic adenocarcinoma entered the study receive external beam irradiation chemotherapy. Radiation therapy consisted of 60 Gy in 3 courses (20 each course) delivered over a period 2 weeks, 2-week rest between courses. Chemotherapy 5 fluorouracil, 500 mg/m , plus cisplatinum, 20 administered on days 1,2 and radiation course. Of evaluable patients, 10 were males 12 females; their median age was 63 years (range, 32-77), performance...
(1998). Breast Angiosarcoma after Conservative Surgery, Radiotherapy and Prosthesis Implant. Acta Oncologica: Vol. 37, No. 2, pp. 209-211.
AbstractCombined total body irradiation (TBI) and Prednimustine were prospectively evaluated in 30 patients affected either with chronic lymphocytic leukemia (CLL) or low-grade non-Hodgkin's lymphoma (NHL) eleven previously treated. Between January 1984 May 1987, 20 evaluable CLL, median age 66 years (range 43–82), classified according to Rai (4 stage I, 10 II, 4 III, 2 IV) NHL malignancy the Working Formulation, Stages III IV, 54 32–71) treated using a 6 MeV Linear Accelerator, applying two...
This retrospective study was conducted on 255 consecutive patients with locally advanced squamous-cell carcinoma of the oral cavity, oropharynx, larynx or hypopharynx, treated at Radiotherapy Department Pordenone General Hospital between January 1975 and December 1985. All underwent radical surgery followed, after an interval ranging from 10 days to 2.9 months, by radiotherapy given either through a 6 MeV linear accelerator cobalt-60 unit. Field extension dose delivered were comparable in...
Between 1978 and 1988, 108 consecutive patients with malignant gliomas were treated. The divided into 3 groups as follows: Group I, surgery if possible, otherwise biopsy followed by whole-brain irradiation to a total dose of 34 Gy in 4 fractions, VCR (2 mg i.v.), BCNU (80 mg/m2 i.v.) repeated every 6 weeks; II received I plus VP16 (75 mg/m2) weeks (50 III 60 30 fractions the tumor bed CDDP (15 weeks. In group 28 had stable disease (SD) 2 showed progression (PRO). Median survival time was 9...