A5043036390- Testicular diseases and treatments
- Renal cell carcinoma treatment
- Sarcoma Diagnosis and Treatment
- Renal and related cancers
- Bladder and Urothelial Cancer Treatments
- Urologic and reproductive health conditions
- Urinary and Genital Oncology Studies
- Cancer Genomics and Diagnostics
- Neuroblastoma Research and Treatments
- Sexual Differentiation and Disorders
- Urological Disorders and Treatments
- Ovarian cancer diagnosis and treatment
- Sperm and Testicular Function
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Glioma Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Multiple Myeloma Research and Treatments
- Neuroendocrine Tumor Research Advances
- Cardiac tumors and thrombi
- Medical Imaging and Pathology Studies
- Eosinophilic Esophagitis
- Cancer, Hypoxia, and Metabolism
- Tumors and Oncological Cases
- Viral-associated cancers and disorders
- IgG4-Related and Inflammatory Diseases
Indiana University – Purdue University Indianapolis
2016-2025
Indiana University School of Medicine
2016-2025
Indus Hospital
2025
Lahore General Hospital
2025
Indiana University
2012-2024
Cleveland Clinic
2022
Indiana University Health
2015-2022
University of Chicago Medical Center
2022
University of Toronto
2022
University of Pittsburgh Medical Center
2022
Fumarate hydratase-deficient renal cell carcinoma (FH-deficient RCC) is a rare and recently described entity associated with hereditary leiomyomatosis RCC syndrome. FH-deficient may show variable clinical pathologic findings, but commonly presents locally advanced metastatic disease carries poor prognosis. We identified 32 patients RCC, confirmed by FH immunohistochemistry (IHC) and/or mutation analysis, performed retrospective review of the features. Median age at presentation was 43 years...
We evaluated the clinicopathologic and chromosomal characteristics of a distinct subset papillary renal tumors compared them to control series cell carcinoma types 1 2. Of 18 patients, 9 were women men, ranging in age from 46 80 years (mean, 64 y; median, 66 y). The ranged diameter 0.6 3 cm 1.63 cm; 1.4 cm). Fourteen WHO/ISUP grade 2 4 1. All stage category pT1. had branching papillae with thin fibrovascular cores, covered by cuboidal columnar cells granular eosinophilic cytoplasm, smooth...
Yolk sac tumors may exhibit numerous patterns. One that has received little attention overall, yet is not uncommon, a solid pattern, which especially prone to misinterpretation, usually as seminoma, in biopsy specimens from metastatic or mediastinal sites. This distinction of critical importance the 2 are treated differently. To determine features useful diagnosis yolk tumor we reviewed 52 germ cell (28 testicular primaries, 21 metastases testis, and 3 primaries) had component with foci...
Low-grade oncocytic tumour (LOT) of the kidney has recently emerged as a potential novel type. Despite similarity to oncocytoma or eosinophilic chromophobe renal cell carcinoma, it shows diffuse keratin 7 immunohistochemistry (IHC) and negative KIT (CD117), which differs from both. We aimed identify molecular characteristics these tumours. Seventeen tumours (one male, 16 female, nine previously published) fitting original description this entity (solid morphology, often with areas cells...
Jain R K, Mehta J, Nakshatri H, Idrees M T & Badve S S(2011) Histopathology58, 766–772High-level expression of forkhead-box protein A1 in metastatic prostate cancer Aims: Expression (FOXA1), a transcription factor important for normal development the gland, is thought to be controlled by steroid hormones and GATA3. The aim this study was investigate potential role FOXA1 GATA3 factors as prognostic cancer. Methods results: FOXA1, androgen receptor (AR) retrospectively analysed...
In recent years, there have been increasing indications for percutaneous renal biopsy. Fine-needle aspiration (FNA), with or without core needle biopsy (CB), has used increasingly in the management of tumors at study institution.A computerized search laboratory records was conducted to retrieve FNA cases masses as well correlating CB and/or nephrectomy specimens. The spanned a period 10 years (2006-2015). diagnoses were classified into 5 categories: malignant, suspicious malignancy,...
Aims Renal cell carcinoma, unclassified (RCCU) is a category that includes morphologically and biologically heterogeneous group of tumours are unable to be diagnosed as other well‐defined entities. We aim describe the morphological findings within this determine most frequent features leading classification difficulty. Methods results One hundred thirty‐six cases RCCU were examined. Patients ranged in age from 23 87 years. Seventy‐seven patients men 59 women. International Society Urological...
Background: The global rise of antimicrobial resistance (AMR) has become a critical healthcare challenge, threatening effective treatment infections. Carbapenem-resistant Enterobacterales (CRE), which include pathogens such as Escherichia coli and Klebsiella pneumoniae, have emerged significant contributors to morbidity mortality, particularly in hospitalized patients. These bacteria are resistant carbapenems, often the last-line antibiotics for multidrug-resistant Gram-negative This study...
Aims Benign tumours of the rete testis include mostly cystadenomas and adenomas. A subset with tubular or tubulopapillary architecture shows morphological similarities to Sertoli cell tumours; these neoplasms were previously termed “Sertoliform testis”. In most recent WHO classification, they have been interpreted as tumours, not otherwise specified (NOS), pure intra‐rete growth, therefore excluded an entity. The remaining vaguely resemble Mullerian origin arising in ovaries. this study we...
Distinguishing between renal oncocytic tumors, such as oncocytoma (RO), and a subset of tumors with overlapping characteristics, including the recently identified low-grade tumor (LOT), can present diagnostic challenge for pathologists owing to shared histopathologic features. To develop an automatic computational classifier stratifying whole slide images biopsy resection specimens into 2 distinct groups: RO LOT. A total 269 from 125 cases across 6 institutions were collected. weakly...