A5044882579- Mesenchymal stem cell research
- Obesity, Physical Activity, Diet
- Gastric Cancer Management and Outcomes
- Children's Physical and Motor Development
- Extracellular vesicles in disease
- Bone Tissue Engineering Materials
- High Altitude and Hypoxia
- Virus-based gene therapy research
- Cardiovascular and exercise physiology
- Graphene and Nanomaterials Applications
- Lung Cancer Treatments and Mutations
- MicroRNA in disease regulation
- Hippo pathway signaling and YAP/TAZ
- Lung Cancer Diagnosis and Treatment
- Diet and metabolism studies
- 3D Printing in Biomedical Research
- Child Nutrition and Water Access
- Magnetic Properties of Alloys
- Cervical Cancer and HPV Research
- Magnetic and transport properties of perovskites and related materials
- Advanced Photocatalysis Techniques
- Cancer-related molecular mechanisms research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cellular Mechanics and Interactions
- Electronic and Structural Properties of Oxides
East China Normal University
2019-2025
Hainan University
2023-2025
Shanxi Agricultural University
2024
Peking University
2021-2024
Xijing Hospital
2022-2024
Air Force Medical University
2022-2024
Tianjin University of Science and Technology
2024
Baotou Research Institute of Rare Earths
2022-2024
Northeast Agricultural University
2024
National Clinical Research Center for Digestive Diseases
2024
MYB transcription factors have been demonstrated to play key regulatory roles in plant growth, development and abiotic stress response. However, knowledge concerning the involvement of rice genes salinity drought resistance are largely unknown. In present study, we cloned characterized OsMYB6 gene, which was induced by stress. Subcellular localization OsMYB6-YFP fusion protein protoplast cells indicated that localized nucleus. Overexpression did not suggest a negative effect on growth...
Abstract Nanozymes, as one of the most efficient reactive oxygen species (ROS)‐scavenging biomaterials, are receiving wide attention in promoting diabetic wound healing. Despite recent attempts at improving catalytic efficiency Pt‐based nanozymes (e.g., PtCu, best systems), they still display quite limited ROS scavenging capacity and ROS‐dependent antibacterial effects on bacteria or immunocytes, which leads to uncontrolled poor Hence, a new class multifunctional PtCuTe nanosheets with...
Endothelial tip cell outgrowth of blood-vessel sprouts marks the initiation angiogenesis which is critical in physiological and pathophysiological procedures. However, how mechanical characteristics extracellular matrix (ECM) modulates formation has been largely neglected. In this study, we found enhanced CD31 expression stiffening outer layer hepatocellular carcinoma than surrounding soft tissues. Stiffened promoted sprouting from endothelial (EC) spheroids upregulated expressions...
Abstract Macrophages play a pivotal role in the immunological cascade activated response to biomedical implants, which predetermine acceptance or rejection of implants by host via pro‐ and anti‐inflammatory polarisation states. The chemical signals macrophage is well‐established, but how physical cues regulate function that may fundamental implant‐bone interface, remains poorly understood. Here we find bone marrow‐derived macrophages (BMDM) cultured on polyacrylamide gels varying stiffness...
Abstract The repair of bone defects in diabetes remains a major challenge the field biomedicine because disturbance immune homeostasis and susceptibility exposed wounds to bacterial infection. Clinically, immunoregulation by removing excessive reactive oxygen species (ROS) effectively promotes diabetic defect repair. However, aggressive ROS clearance can disrupt homeostasis, making ROS‐mediated polarization M2 macrophages process tissue healing be difficult. Herein, an ultrathin defective...
Abstract Angiogenesis is a complex, highly-coordinated and multi-step process of new blood vessel formation from pre-existing vessels. When initiated, the sprouting spearheaded by specialized endothelial cells (ECs) known as tip cells, which guide organization accompanying stalk determine function morphology finally-formed Recent studies indicate that orchestration coordination angiogenesis involve dynamic cell selection, competitive selection to lead angiogenic sprouts. Therefore, this...
Abstract Bone tissue renewal can be enhanced through co-transplantation of bone mesenchymal stem cells (BMSCs) and vascular endothelial (ECs). However, there are apparent limitations in cell-based therapy which hinder its clinic translation. Hence, we investigated the potential alternative cell substitutes for facilitating regeneration. In this study, successfully prepared membrane vesicles (CMVs) from BMSCs ECs. The results showed that BMSC-derived (BMSC-CMVs) possessed receptors involved...
Mesenchymal stem cell (MSC) migration determines the healing capacity of bone and is crucial in promoting regeneration. Migration MSCs highly dependent on degradation extracellular matrix by proteolytic enzymes. However, underlying mechanisms how enzymolysis paves way for to migrate from their niche defect area still not fully understood. Here, this study shows that high-temperature requirement A3 (HtrA3) overcomes physical barrier provides anchor points through collagen IV degradation,...
Abstract Angiogenesis is crucial for successful bone defect repair. Co‐transplanting Bone Marrow Stromal Cells (BMSCs) and Endothelial (ECs) has shown promise vascular augmentation, but it face challenges in hostile tissue microenvironments, including poor cell survival limited efficacy. In this study, the mitochondria of human BMSCs are isolated transplanted to from same batch passage number (BMSCs mito ). The significantly boosted ability ‐ECs promote angiogenesis, as assessed by vitro...
Abstract Regenerating periodontal bone defect surrounding tissue is crucial for orthodontic or dental implant treatment. The declined osteogenic ability of ligament stem cells (PDLSCs) induced by inflammation stimulus contributes to reduced capacity regenerate bone, which brings about a huge challenge treating periodontitis. Here, inspired the adhesive property mussels, we have created and mineralized hydrogel microspheres loaded with traditional compound cordycepin (MMS-CY). MMS-CY could...
Katsumada galangal seed (Alpinia hainanensis K. Schum) is an important member of the Zingiberaceae family, with both medicinal value and culinary applications (Park et al. 2020). In May 2023, a stem disease Al. was detected in 100-acre plantation located Danzhou City, Hainan Province China, average incidence 15% to 20%. The primarily targeted basal stems, pathogen spreading by mycelia soil around rhizome, reaching neighboring plants. infection caused base undergo necrosis, turning tissue...
Background To investigate the association between family socioeconomic status (SES) and physical activity (PA) levels of adolescents, as well moderating effect gender on this relationship. Methods A total 10,327 Chinese adolescents aged 12–17 were recruited to complete questionnaires regarding their SES PA levels. “Physical Activity Questionnaire for Children Adolescents Aged 7–18 Years” was utilized examine specific items, intensity, duration, frequency PA. The Kruskal–Wallis test...
<title>Abstract</title> <bold>Background:</bold> Poor sleep quality is a prevalent health concern among Chinese adolescents. Although significant focus has been given to the impact of problems on cognitive function, research association between and working memory in typically developing adolescents remains limited. The aim this study examine <bold>Methods: </bold>The present randomly recruited 2428 aged 12-18 years from four schools Shanghai Suzhou, eastern China 2023 through two-stage...
ATP-binding cassette (ABC) transporter proteins are a gene super-family in plants and play vital roles growth, development, response to abiotic biotic stresses. The ABC transporters have been identified crop such as rice buckwheat, but little is known about them soybean. Soybean an important oil one of the five major crops world. In this study, 255 genes that putatively encode were from soybean through bioinformatics then categorized into eight subfamilies, including 7 ABCAs, 52 ABCBs, 48...
Pulmonary function is very important for the healthy development of children and adolescents. However, fewer studies have been conducted on pulmonary trends in adolescents remote areas. The aim this study was to estimate forced vital capacity (FVC) trend its relationship with body mass index (BMI) among young people Xinjiang during 1985-2014 using data from seven successive national surveys.