A5006158088- Multiple Sclerosis Research Studies
- Systemic Lupus Erythematosus Research
- Acute Ischemic Stroke Management
- Psoriasis: Treatment and Pathogenesis
- Rheumatoid Arthritis Research and Therapies
- Neuroinflammation and Neurodegeneration Mechanisms
- Folate and B Vitamins Research
- Asthma and respiratory diseases
- Systemic Sclerosis and Related Diseases
- Adipokines, Inflammation, and Metabolic Diseases
- Cytokine Signaling Pathways and Interactions
- Dermatology and Skin Diseases
- Atherosclerosis and Cardiovascular Diseases
- Vitamin D Research Studies
- T-cell and Retrovirus Studies
- T-cell and B-cell Immunology
- Acute Lymphoblastic Leukemia research
- Monoclonal and Polyclonal Antibodies Research
- Cell Adhesion Molecules Research
- HIV-related health complications and treatments
- Cerebrovascular and Carotid Artery Diseases
- Autoimmune and Inflammatory Disorders Research
- Peripheral Neuropathies and Disorders
- HER2/EGFR in Cancer Research
- Inflammatory Bowel Disease
Universidade Estadual de Londrina
2015-2024
Pontifícia Universidade Católica do Paraná
2024
Objective The aim of this study was to report the frequency autoimmune disorders and autoantibodies in 22 patients with neuromyelitis optica (NMO), as well whether seropositivity for differs between anti-aquaporin 4 (AQP4) positive AQP4 negative NMO patients. Methods Demographic, medical records, a profile were evaluated patients, including AQP4, anti-thyroid-stimulating hormone receptor, antinuclear antibodies (ANA), anti-thyroperoxidase (anti-TPO), anti-thyroglobulin (anti-Tg),...
Background This study was performed to assess adhesion molecules in systemic lupus erythematosus (SLE). Methods case-control examined 126 SLE patients and 48 healthy individuals. Blood levels of six molecules, cortisol, nuclear autoantibody (ANA) anti-double stranded DNA (anti-dsDNA) titers were measured, while disease activity assessed using the Disease Activity Index (SLEDAI) score. Results Platelet endothelial cell molecule 1 (PECAM-1), vascular (VCAM-1), E-selectin, P-selectin,...
Granulocyte-colony stimulating factor (G-CSF) is a current pharmacological approach to increase peripheral neutrophil counts after anti-tumor therapies. Pain most relevant side effect of G-CSF in healthy volunteers and cancer patients. Therefore, the mechanisms G-CSF-induced hyperalgesia were investigated focusing on role spinal mitogen-activated protein (MAP) kinases ERK (extracellular signal-regulated kinase), JNK (Jun N-terminal Kinase) p38, PI(3)K (phosphatidylinositol 3-kinase). induced...
Only a small proportion of women who are exposed to infection with high-risk human papillomavirus (HR-HPV) progress persistent and develop cervical cancer (CC). The immune response genetic background the host may affect risk progression from HR-HPV lesions cancer. However, our knowledge, no studies has been conducted evaluate relationship between variability leukocyte antigens (HLA) genes serum cytokine expression in this pathology. In current study, we examined associations HLA alleles...